Ensembl ID ENSG00000165271 Gene ID 65083 Accession 19910
Gene Symbol NOL6 Alias NRAP;UTP22;bA311H10.1 Full Name nucleolar protein 6
Position 9 : 33461353 - 33473930 Length 12578 bases Strand Minus strand
Status Confidence Main interacting RNAsrRNARBP type Canonical_RBPs
Summary The nucleolus is a dense subnuclear membraneless organelle that assembles around clusters of rRNA genes and functions in ribosome biogenesis. This gene encodes a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. Alternative splicing has been observed at this locus and two splice variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]

ENSG00000165271 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000165271 NOL6 0.41 2.55e-21 BRCA
ENSG00000165271 NOL6 1.04 2.10e-37 COAD
ENSG00000165271 NOL6 0.73 1.00e-12 KICH
ENSG00000165271 NOL6 0.75 1.37e-11 LUSC
ENSG00000165271 NOL6 0.40 2.35e-12 PRAD
ENSG00000165271 NOL6 0.88 7.24e-13 STAD
ENSG00000165271 NOL6 0.71 1.34e-19 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000165271 NOL6 MESO 0.034 high
ENSG00000165271 NOL6 STAD 0.033 low
ENSG00000165271 NOL6 CHOL 0.041 high
ENSG00000165271 NOL6 UCEC 0.045 low
ENSG00000165271 NOL6 THCA 0.00098 high
ENSG00000165271 NOL6 ACC 0.0027 high
ENSG00000165271 NOL6 LUSC 0.0046 high
ENSG00000165271 NOL6 READ 0.0093 low
ENSG00000165271 NOL6 KIRP 0.024 low
ENSG00000165271 NOL6 PCPG 0.012 low
ENSG00000165271 NOL6 BRCA 0.025 high
ENSG00000165271 NOL6 COAD 0.023 high
ENSG00000165271 NOL6 UCS 0.022 high
ENSG00000165271 NOL6 ESCA 0.0036 low
ENSG00000165271 NOL6 KIRC 0.014 high
ENSG00000165271 NOL6 PRAD 0.04 low
ENSG00000165271 NOL6 SKCM 0.0075 high
ENSG00000165271 NOL6 CESC 0.027 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000165271 NOL6 LUSC Amp 7.006534 0.345359 0.684105 0.271457
ENSG00000165271 NOL6 GBM Del 2.121499 0.068487 0.637672 0.339688
ENSG00000165271 NOL6 HNSC Amp 1.897189 0.145449 0.592132 0.247126
ENSG00000165271 NOL6 STAD Amp 0.981259 0.140238 0.528160 0.192744