Ensembl ID ENSG00000164896 Gene ID 10922 Accession 24676
Gene Symbol FASTK Alias FAST Full Name Fas activated serine/threonine kinase
Position 7 : 151076624 - 151080862 Length 4239 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008]

ENSG00000164896 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000164896 FASTK 0.70 5.77e-23 BRCA
ENSG00000164896 FASTK 1.18 4.23e-17 KICH
ENSG00000164896 FASTK 0.91 2.48e-31 LUSC
ENSG00000164896 FASTK 0.90 6.17e-13 KIRP
ENSG00000164896 FASTK 0.68 4.01e-14 LIHC
ENSG00000164896 FASTK 0.85 2.42e-21 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000164896 FASTK tumor 17695722
ENSG00000164896 FASTK tumors 19077453
ENSG00000164896 FASTK tumor 24013584
ENSG00000164896 FASTK breast cancer 29700004
ENSG00000164896 FASTK cancer 30040903
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000164896 FASTK MESO 0.016 high
ENSG00000164896 FASTK SARC 0.016 low
ENSG00000164896 FASTK STAD 0.036 low
ENSG00000164896 FASTK UVM 0.0084 high
ENSG00000164896 FASTK PAAD 0.00073 low
ENSG00000164896 FASTK LGG 0.007 high
ENSG00000164896 FASTK LUSC 0.0025 low
ENSG00000164896 FASTK HNSC 0.0022 low
ENSG00000164896 FASTK KIRP 0.0014 low
ENSG00000164896 FASTK KICH 0.045 high
ENSG00000164896 FASTK COAD 0.0028 high
ENSG00000164896 FASTK ESCA 0.015 low
ENSG00000164896 FASTK OV 0.004 low
ENSG00000164896 FASTK BLCA 0.018 low
ENSG00000164896 FASTK GBM 0.00062 high
ENSG00000164896 FASTK SKCM 0.0048 high
ENSG00000164896 FASTK CESC 0.01 low
ENSG00000164896 FASTK LIHC 0.0022 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000164896 FASTK LUSC Del 2.308683 0.086655 0.360084 0.181637
ENSG00000164896 FASTK LAML Del 3.345981 0.064052 0.727916 0.130890
ENSG00000164896 FASTK LGG Amp 5.105686 0.101190 0.672145 0.339181
ENSG00000164896 FASTK CESC Del 1.961895 0.090282 0.486420 0.206780
ENSG00000164896 FASTK SARC Del 1.411190 0.142387 0.521165 0.229572
ENSG00000164896 FASTK PAAD Del 0.961741 0.051191 0.380819 0.081522
ENSG00000164896 FASTK ESCA Del 7.839217 0.247715 0.444361 0.347826
ENSG00000164896 FASTK SKCM Amp 3.972537 0.216844 0.715484 0.585831
ENSG00000164896 FASTK HNSC Del 20.508295 0.174220 0.417495 0.249042
ENSG00000164896 FASTK BRCA Del 1.334522 0.069270 0.417818 0.170370
ENSG00000164896 FASTK STAD Del 3.917165 0.098691 0.359988 0.199546
ENSG00000164896 FASTK UCEC Del 1.429979 0.057246 0.498886 0.109462
ENSG00000164896 FASTK OV Amp 9.879792 0.544822 0.751004 0.525043