Ensembl ID
ENSG00000164163
Gene ID
6059
Accession
69
Gene Symbol
ABCE1
Alias
RLI;OABP;RLI1;ABC38;RNS4I;RNASEL1;RNASELI
Full Name
ATP binding cassette subfamily E member 1
Position
4 : 145098288 - 145129524
Length
31237 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs ncRNA RBP type
Canonical_RBPs
Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
ENSG00000164163 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000164163
ABCE1
0.99
2.60e-23
COAD
ENSG00000164163
ABCE1
0.70
1.85e-22
LUSC
ENSG00000164163
ABCE1
0.90
1.05e-16
STAD
ENSG00000164163
ABCE1
0.54
1.49e-14
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000164163
ABCE1
cancer
14871991
ENSG00000164163
ABCE1
colon cancer
15809757
ENSG00000164163
ABCE1
cancer
16421098
ENSG00000164163
ABCE1
prostate cancer
18189233
ENSG00000164163
ABCE1
colorectal cancer
19723883
ENSG00000164163
ABCE1
cancer
19879105
ENSG00000164163
ABCE1
small cell lung cancer
20372810
ENSG00000164163
ABCE1
tumor
20631307
ENSG00000164163
ABCE1
cancer
22267055
ENSG00000164163
ABCE1
tumours
22294766
ENSG00000164163
ABCE1
cancer
22925698
ENSG00000164163
ABCE1
tumor
23008114
ENSG00000164163
ABCE1
Tumor
23354868
ENSG00000164163
ABCE1
tumors
23556449
ENSG00000164163
ABCE1
tumor
24349876
ENSG00000164163
ABCE1
tumor
24551278
ENSG00000164163
ABCE1
lung cancer
25070080
ENSG00000164163
ABCE1
cancer
25072059
ENSG00000164163
ABCE1
oral cancer
25337191
ENSG00000164163
ABCE1
lung cancer
25744244
ENSG00000164163
ABCE1
esophageal cancer
25815591
ENSG00000164163
ABCE1
tumor
26019700
ENSG00000164163
ABCE1
tumor
26205301
ENSG00000164163
ABCE1
tumor
26284063
ENSG00000164163
ABCE1
lung cancer
26617714
ENSG00000164163
ABCE1
lung cancer
26733164
ENSG00000164163
ABCE1
Tumor
27109616
ENSG00000164163
ABCE1
tumor
27217584
ENSG00000164163
ABCE1
lung cancer
27314749
ENSG00000164163
ABCE1
tumor
28706438
ENSG00000164163
ABCE1
tumor
28906339
ENSG00000164163
ABCE1
lung cancer
29145194
ENSG00000164163
ABCE1
tumor
29299660
ENSG00000164163
ABCE1
lung cancer
30214518
ENSG00000164163
ABCE1
breast cancer
30214553
ENSG00000164163
ABCE1
tumor
30305609
ENSG00000164163
ABCE1
cancer
30455394
ENSG00000164163
ABCE1
lung cancer
30936993
ENSG00000164163
ABCE1
breast cancer
31007850
ENSG00000164163
ABCE1
lung cancer
31306106
ENSG00000164163
ABCE1
lung cancer
31501431
ENSG00000164163
ABCE1
cancer
31691568
ENSG00000164163
ABCE1
squamous cell cancer
31841188
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000164163
ABCE1
MESO
0.0036
high
show
ENSG00000164163
ABCE1
SARC
0.023
high
show
ENSG00000164163
ABCE1
UVM
0.0083
high
show
ENSG00000164163
ABCE1
PAAD
0.00015
high
show
ENSG00000164163
ABCE1
UCEC
0.04
high
show
ENSG00000164163
ABCE1
THCA
0.02
high
show
ENSG00000164163
ABCE1
ACC
0.00017
high
show
ENSG00000164163
ABCE1
LGG
0.011
high
show
ENSG00000164163
ABCE1
HNSC
0.0042
high
show
ENSG00000164163
ABCE1
READ
0.0014
low
show
ENSG00000164163
ABCE1
KIRP
0.00019
high
show
ENSG00000164163
ABCE1
KICH
0.00015
high
show
ENSG00000164163
ABCE1
LUAD
0.0061
high
show
ENSG00000164163
ABCE1
BRCA
0.0025
high
show
ENSG00000164163
ABCE1
COAD
0.01
low
show
ENSG00000164163
ABCE1
KIRC
0.017
low
show
ENSG00000164163
ABCE1
SKCM
0.002
low
show
ENSG00000164163
ABCE1
CESC
0.0078
high
show
ENSG00000164163
ABCE1
LIHC
0.0014
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000164163
ABCE1
LUSC
Del
3.419684
0.098325
0.386412
0.628743
ENSG00000164163
ABCE1
LGG
Del
5.131842
0.075764
0.443747
0.239766
ENSG00000164163
ABCE1
BLCA
Del
0.712188
0.076953
0.351740
0.382353
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