Ensembl ID ENSG00000164163 Gene ID 6059 Accession 69
Gene Symbol ABCE1 Alias RLI;OABP;RLI1;ABC38;RNS4I;RNASEL1;RNASELI Full Name ATP binding cassette subfamily E member 1
Position 4 : 145098288 - 145129524 Length 31237 bases Strand Plus strand
Status Confidence Main interacting RNAsncRNARBP type Canonical_RBPs
Summary The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

ENSG00000164163 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000164163 ABCE1 0.99 2.60e-23 COAD
ENSG00000164163 ABCE1 0.70 1.85e-22 LUSC
ENSG00000164163 ABCE1 0.90 1.05e-16 STAD
ENSG00000164163 ABCE1 0.54 1.49e-14 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000164163 ABCE1 cancer 14871991
ENSG00000164163 ABCE1 colon cancer 15809757
ENSG00000164163 ABCE1 cancer 16421098
ENSG00000164163 ABCE1 prostate cancer 18189233
ENSG00000164163 ABCE1 colorectal cancer 19723883
ENSG00000164163 ABCE1 cancer 19879105
ENSG00000164163 ABCE1 small cell lung cancer 20372810
ENSG00000164163 ABCE1 tumor 20631307
ENSG00000164163 ABCE1 cancer 22267055
ENSG00000164163 ABCE1 tumours 22294766
ENSG00000164163 ABCE1 cancer 22925698
ENSG00000164163 ABCE1 tumor 23008114
ENSG00000164163 ABCE1 Tumor 23354868
ENSG00000164163 ABCE1 tumors 23556449
ENSG00000164163 ABCE1 tumor 24349876
ENSG00000164163 ABCE1 tumor 24551278
ENSG00000164163 ABCE1 lung cancer 25070080
ENSG00000164163 ABCE1 cancer 25072059
ENSG00000164163 ABCE1 oral cancer 25337191
ENSG00000164163 ABCE1 lung cancer 25744244
ENSG00000164163 ABCE1 esophageal cancer 25815591
ENSG00000164163 ABCE1 tumor 26019700
ENSG00000164163 ABCE1 tumor 26205301
ENSG00000164163 ABCE1 tumor 26284063
ENSG00000164163 ABCE1 lung cancer 26617714
ENSG00000164163 ABCE1 lung cancer 26733164
ENSG00000164163 ABCE1 Tumor 27109616
ENSG00000164163 ABCE1 tumor 27217584
ENSG00000164163 ABCE1 lung cancer 27314749
ENSG00000164163 ABCE1 tumor 28706438
ENSG00000164163 ABCE1 tumor 28906339
ENSG00000164163 ABCE1 lung cancer 29145194
ENSG00000164163 ABCE1 tumor 29299660
ENSG00000164163 ABCE1 lung cancer 30214518
ENSG00000164163 ABCE1 breast cancer 30214553
ENSG00000164163 ABCE1 tumor 30305609
ENSG00000164163 ABCE1 cancer 30455394
ENSG00000164163 ABCE1 lung cancer 30936993
ENSG00000164163 ABCE1 breast cancer 31007850
ENSG00000164163 ABCE1 lung cancer 31306106
ENSG00000164163 ABCE1 lung cancer 31501431
ENSG00000164163 ABCE1 cancer 31691568
ENSG00000164163 ABCE1 squamous cell cancer 31841188
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000164163 ABCE1 MESO 0.0036 high
ENSG00000164163 ABCE1 SARC 0.023 high
ENSG00000164163 ABCE1 UVM 0.0083 high
ENSG00000164163 ABCE1 PAAD 0.00015 high
ENSG00000164163 ABCE1 UCEC 0.04 high
ENSG00000164163 ABCE1 THCA 0.02 high
ENSG00000164163 ABCE1 ACC 0.00017 high
ENSG00000164163 ABCE1 LGG 0.011 high
ENSG00000164163 ABCE1 HNSC 0.0042 high
ENSG00000164163 ABCE1 READ 0.0014 low
ENSG00000164163 ABCE1 KIRP 0.00019 high
ENSG00000164163 ABCE1 KICH 0.00015 high
ENSG00000164163 ABCE1 LUAD 0.0061 high
ENSG00000164163 ABCE1 BRCA 0.0025 high
ENSG00000164163 ABCE1 COAD 0.01 low
ENSG00000164163 ABCE1 KIRC 0.017 low
ENSG00000164163 ABCE1 SKCM 0.002 low
ENSG00000164163 ABCE1 CESC 0.0078 high
ENSG00000164163 ABCE1 LIHC 0.0014 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000164163 ABCE1 LUSC Del 3.419684 0.098325 0.386412 0.628743
ENSG00000164163 ABCE1 LGG Del 5.131842 0.075764 0.443747 0.239766
ENSG00000164163 ABCE1 BLCA Del 0.712188 0.076953 0.351740 0.382353