Ensembl ID
ENSG00000164104
Gene ID
3148
Accession
5000
Gene Symbol
HMGB2
Alias
HMG2
Full Name
high mobility group box 2
Position
4 : 173331376 - 173334391
Length
3016 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs N.A. RBP type
Non-canonical_RBPs
Summary
This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. [provided by RefSeq, Jul 2008]
ENSG00000164104 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000164104
1.12
1.16e-42
BRCA
ENSG00000164104
1.30
1.03e-34
LUSC
ENSG00000164104
2.23
1.84e-14
GBM
ENSG00000164104
1.37
1.08e-25
LIHC
ENSG00000164104
0.86
1.53e-14
LUAD
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000164104
STAD
0.018
low
show
ENSG00000164104
UVM
0.004
high
show
ENSG00000164104
PAAD
8e-04
high
show
ENSG00000164104
THCA
0.029
high
show
ENSG00000164104
LUSC
0.027
low
show
ENSG00000164104
HNSC
0.015
high
show
ENSG00000164104
KIRP
0.00014
high
show
ENSG00000164104
LUAD
0.013
high
show
ENSG00000164104
THYM
0.0075
low
show
ENSG00000164104
UCS
0.0037
low
show
ENSG00000164104
ESCA
0.023
high
show
ENSG00000164104
OV
0.03
low
show
ENSG00000164104
DLBC
0.041
low
show
ENSG00000164104
TGCT
0.029
low
show
ENSG00000164104
BLCA
0.01
low
show
ENSG00000164104
LAML
0.0036
low
show
ENSG00000164104
SKCM
0.0016
low
show
ENSG00000164104
CESC
0.015
low
show
ENSG00000164104
LIHC
0.00021
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000164104
LUSC
Del
11.696576
0.160993
0.401161
0.668663
ENSG00000164104
LUAD
Del
5.966560
0.100082
0.313430
0.360465
ENSG00000164104
LGG
Del
10.319233
0.105944
0.467530
0.255361
ENSG00000164104
CESC
Del
2.162335
0.093585
0.464725
0.362712
ENSG00000164104
KIRP
Del
0.740219
0.027066
0.585346
0.100694
ENSG00000164104
ACC
Del
1.275548
0.121497
0.534461
0.166667
ENSG00000164104
COAD
Del
6.188298
0.088821
0.437893
0.321508
ENSG00000164104
SARC
Del
4.205238
0.202628
0.489844
0.322957
ENSG00000164104
GBM
Del
1.794513
0.065109
0.446280
0.140381
ENSG00000164104
ESCA
Del
1.683171
0.124152
0.419278
0.532609
ENSG00000164104
SKCM
Del
0.756059
0.067260
0.428657
0.256131
ENSG00000164104
HNSC
Del
6.488808
0.101628
0.369013
0.360153
ENSG00000164104
LIHC
Del
7.497599
0.145426
0.565857
0.440541
ENSG00000164104
BLCA
Del
6.546640
0.148864
0.382104
0.411765
ENSG00000164104
BRCA
Del
4.906738
0.092125
0.401665
0.312037
ENSG00000164104
STAD
Del
10.783017
0.150491
0.369366
0.437642
ENSG00000164104
UCEC
Del
1.959666
0.062870
0.467550
0.218924
ENSG00000164104
KIRC
Del
0.762468
0.025016
0.328852
0.147727
ENSG00000164104
OV
Del
14.791594
0.342185
0.641874
0.696028
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