Ensembl ID ENSG00000164022 Gene ID 9255 Accession 10648
Gene Symbol AIMP1 Alias p43;HLD3;EMAP2;SCYE1;EMAPII Full Name aminoacyl tRNA synthetase complex interacting multifunctional protein 1
Position 4 : 106315544 - 106349456 Length 33913 bases Strand Plus strand
Status Confidence Main interacting RNAstRNARBP type Canonical_RBPs
Summary The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. [provided by RefSeq, Dec 2008]

ENSG00000164022 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000164022 AIMP1 tumor 16682815
ENSG00000164022 AIMP1 cancer 17443684
ENSG00000164022 AIMP1 tumor 18793691
ENSG00000164022 AIMP1 tumor 19573982
ENSG00000164022 AIMP1 tumor 21416500
ENSG00000164022 AIMP1 colorectal cancer 21789020
ENSG00000164022 AIMP1 cancer 22952576
ENSG00000164022 AIMP1 tumor 26613952
ENSG00000164022 AIMP1 GBM 27225222
ENSG00000164022 AIMP1 tumor 28381637
ENSG00000164022 AIMP1 tumor 29379495
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000164022 AIMP1 STAD 0.041 low
ENSG00000164022 AIMP1 UVM 0.014 high
ENSG00000164022 AIMP1 ACC 0.022 high
ENSG00000164022 AIMP1 KICH 0.0033 high
ENSG00000164022 AIMP1 LUAD 0.032 high
ENSG00000164022 AIMP1 BRCA 0.0013 high
ENSG00000164022 AIMP1 UCS 0.019 high
ENSG00000164022 AIMP1 OV 0.042 low
ENSG00000164022 AIMP1 KIRC 0.00047 low
ENSG00000164022 AIMP1 PRAD 0.0023 high
ENSG00000164022 AIMP1 BLCA 0.02 low
ENSG00000164022 AIMP1 SKCM 0.00023 low
ENSG00000164022 AIMP1 LIHC 0.0064 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000164022 AIMP1 LIHC Del 5.387979 0.125529 0.557679 0.467568
ENSG00000164022 AIMP1 UCEC Del 0.638781 0.046600 0.444201 0.209647
ENSG00000164022 AIMP1 OV Del 7.283757 0.272813 0.635862 0.715026