Ensembl ID ENSG00000163950 Gene ID 7884 Accession 10904
Gene Symbol SLBP Alias HBP Full Name stem-loop histone mRNA binding protein
Position 4 : 1692731 - 1712344 Length 19614 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene encodes a protein that binds to the stem-loop structure in replication-dependent histone mRNAs. Histone mRNAs do not contain introns or polyadenylation signals, and are processed by endonucleolytic cleavage. The stem-loop structure is essential for efficient processing but this structure also controls the transport, translation and stability of histone mRNAs. Expression of the protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1. [provided by RefSeq, Jul 2008]

ENSG00000163950 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000163950 SLBP 0.62 2.25e-32 BRCA
ENSG00000163950 SLBP 0.76 8.04e-23 COAD
ENSG00000163950 SLBP 1.02 2.10e-25 KICH
ENSG00000163950 SLBP 0.88 8.36e-30 LUSC
ENSG00000163950 SLBP 0.56 9.33e-15 LIHC
ENSG00000163950 SLBP 0.69 4.29e-20 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000163950 SLBP tumour 27402160
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000163950 SLBP SARC 0.0062 high
ENSG00000163950 SLBP UVM 0.0011 high
ENSG00000163950 SLBP PAAD 0.0086 high
ENSG00000163950 SLBP ACC 0.0014 high
ENSG00000163950 SLBP HNSC 0.01 low
ENSG00000163950 SLBP READ 0.012 low
ENSG00000163950 SLBP LUAD 0.0062 high
ENSG00000163950 SLBP THYM 0.0096 low
ENSG00000163950 SLBP BRCA 0.018 high
ENSG00000163950 SLBP UCS 0.008 low
ENSG00000163950 SLBP ESCA 0.03 high
ENSG00000163950 SLBP OV 0.0072 low
ENSG00000163950 SLBP DLBC 0.0073 low
ENSG00000163950 SLBP PRAD 0.0032 high
ENSG00000163950 SLBP SKCM 0.00058 low
ENSG00000163950 SLBP CESC 0.0056 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000163950 SLBP ACC Amp 1.155613 0.307327 1.173523 0.433333
ENSG00000163950 SLBP UCS Amp 5.382402 1.111782 1.254501 0.428571
ENSG00000163950 SLBP PAAD Amp 1.423063 0.106467 0.947139 0.081522
ENSG00000163950 SLBP HNSC Del 2.625651 0.074043 0.418085 0.390805
ENSG00000163950 SLBP BLCA Amp 1.609064 0.196965 0.669229 0.171569
ENSG00000163950 SLBP BRCA Del 0.634066 0.062553 0.421042 0.312037
ENSG00000163950 SLBP STAD Del 0.742987 0.061129 0.358484 0.369615
ENSG00000163950 SLBP PRAD Amp 0.940234 0.049327 0.553407 0.042683
ENSG00000163950 SLBP UCEC Amp 4.163809 0.169634 0.814312 0.096475
ENSG00000163950 SLBP OV Amp 4.428078 0.438127 0.789440 0.283247