Ensembl ID
ENSG00000163950
Gene ID
7884
Accession
10904
Gene Symbol
SLBP
Alias
HBP
Full Name
stem-loop histone mRNA binding protein
Position
4 : 1692731 - 1712344
Length
19614 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs mRNA RBP type
Canonical_RBPs
Summary
This gene encodes a protein that binds to the stem-loop structure in replication-dependent histone mRNAs. Histone mRNAs do not contain introns or polyadenylation signals, and are processed by endonucleolytic cleavage. The stem-loop structure is essential for efficient processing but this structure also controls the transport, translation and stability of histone mRNAs. Expression of the protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1. [provided by RefSeq, Jul 2008]
ENSG00000163950 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000163950
SLBP
0.62
2.25e-32
BRCA
ENSG00000163950
SLBP
0.76
8.04e-23
COAD
ENSG00000163950
SLBP
1.02
2.10e-25
KICH
ENSG00000163950
SLBP
0.88
8.36e-30
LUSC
ENSG00000163950
SLBP
0.56
9.33e-15
LIHC
ENSG00000163950
SLBP
0.69
4.29e-20
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000163950
SLBP
tumour
27402160
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000163950
SLBP
SARC
0.0062
high
show
ENSG00000163950
SLBP
UVM
0.0011
high
show
ENSG00000163950
SLBP
PAAD
0.0086
high
show
ENSG00000163950
SLBP
ACC
0.0014
high
show
ENSG00000163950
SLBP
HNSC
0.01
low
show
ENSG00000163950
SLBP
READ
0.012
low
show
ENSG00000163950
SLBP
LUAD
0.0062
high
show
ENSG00000163950
SLBP
THYM
0.0096
low
show
ENSG00000163950
SLBP
BRCA
0.018
high
show
ENSG00000163950
SLBP
UCS
0.008
low
show
ENSG00000163950
SLBP
ESCA
0.03
high
show
ENSG00000163950
SLBP
OV
0.0072
low
show
ENSG00000163950
SLBP
DLBC
0.0073
low
show
ENSG00000163950
SLBP
PRAD
0.0032
high
show
ENSG00000163950
SLBP
SKCM
0.00058
low
show
ENSG00000163950
SLBP
CESC
0.0056
low
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000163950
SLBP
ACC
Amp
1.155613
0.307327
1.173523
0.433333
ENSG00000163950
SLBP
UCS
Amp
5.382402
1.111782
1.254501
0.428571
ENSG00000163950
SLBP
PAAD
Amp
1.423063
0.106467
0.947139
0.081522
ENSG00000163950
SLBP
HNSC
Del
2.625651
0.074043
0.418085
0.390805
ENSG00000163950
SLBP
BLCA
Amp
1.609064
0.196965
0.669229
0.171569
ENSG00000163950
SLBP
BRCA
Del
0.634066
0.062553
0.421042
0.312037
ENSG00000163950
SLBP
STAD
Del
0.742987
0.061129
0.358484
0.369615
ENSG00000163950
SLBP
PRAD
Amp
0.940234
0.049327
0.553407
0.042683
ENSG00000163950
SLBP
UCEC
Amp
4.163809
0.169634
0.814312
0.096475
ENSG00000163950
SLBP
OV
Amp
4.428078
0.438127
0.789440
0.283247
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