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| Ensembl ID | ENSG00000163931 | Gene ID | 7086 | Accession | 11834 |
| Gene Symbol | TKT | Alias | TK;TKT1;SDDHD;HEL107;HEL-S-48 | Full Name | transketolase |
| Position | 3 : 53224712 - 53256022 | Length | 31311 bases | Strand | Minus strand |
| Status | Confidence | Main interacting RNAs | N.A. | RBP type | Non-canonical_RBPs |
| Summary | This gene encodes a thiamine-dependent enzyme which plays a role in the channeling of excess sugar phosphates to glycolysis in the pentose phosphate pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012] | ||||
ENSG00000163931 Expression In 33 Tumors
| Ensembl ID | Gene symbol | Log2 Foldchange | Pvaue | Cancer |
|---|---|---|---|---|
| ENSG00000163931 | TKT | 1.10 | 8.48e-28 | COAD |
| ENSG00000163931 | TKT | 1.02 | 1.34e-14 | KICH |
| ENSG00000163931 | TKT | 1.35 | 6.83e-12 | READ |
| ENSG00000163931 | TKT | 1.50 | 6.74e-19 | KIRP |
| ENSG00000163931 | TKT | 1.49 | 1.18e-18 | LIHC |
| ENSG00000163931 | TKT | 1.55 | 4.60e-26 | UCEC |
| ENSG00000163931 | TKT | 0.75 | 4.74e-12 | LUAD |
| Ensembl ID | Gene symbol | Cancer types | Pubmed ID |
|---|---|---|---|
| ENSG00000163931 | TKT | tumor | 10080 |
| ENSG00000163931 | TKT | cancer | 10452541 |
| ENSG00000163931 | TKT | tumor | 10890024 |
| ENSG00000163931 | TKT | tumor | 10928186 |
| ENSG00000163931 | TKT | tumour | 11488910 |
| ENSG00000163931 | TKT | tumors | 13766147 |
| ENSG00000163931 | TKT | tumor | 1492388 |
| ENSG00000163931 | TKT | tumor | 14969819 |
| ENSG00000163931 | TKT | tumor | 15296642 |
| ENSG00000163931 | TKT | cancer | 15991799 |
| ENSG00000163931 | TKT | cancer | 16116031 |
| ENSG00000163931 | TKT | cancer | 16465194 |
| ENSG00000163931 | TKT | gastric cancer | 16969476 |
| ENSG00000163931 | TKT | ovarian cancer | 17291239 |
| ENSG00000163931 | TKT | tumor | 17321041 |
| ENSG00000163931 | TKT | breast cancer | 17342325 |
| ENSG00000163931 | TKT | colon cancer | 17351395 |
| ENSG00000163931 | TKT | tumor | 17970065 |
| ENSG00000163931 | TKT | cancer | 18083562 |
| ENSG00000163931 | TKT | tumor | 18182286 |
| ENSG00000163931 | TKT | tumors | 18267359 |
| ENSG00000163931 | TKT | tumor | 18296915 |
| ENSG00000163931 | TKT | tumor | 18302154 |
| ENSG00000163931 | TKT | tumor | 18394773 |
| ENSG00000163931 | TKT | tumours | 18447912 |
| ENSG00000163931 | TKT | cancers | 18615628 |
| ENSG00000163931 | TKT | tumors | 18700018 |
| ENSG00000163931 | TKT | cancer | 19111488 |
| ENSG00000163931 | TKT | tumour | 19139037 |
| ENSG00000163931 | TKT | colon cancer | 19253370 |
| ENSG00000163931 | TKT | lung cancer | 19294702 |
| ENSG00000163931 | TKT | uterine cervix cancer | 19331662 |
| ENSG00000163931 | TKT | cancer | 19465749 |
| ENSG00000163931 | TKT | tumors | 19545368 |
| ENSG00000163931 | TKT | cancers | 19812737 |
| ENSG00000163931 | TKT | cancer | 20035555 |
| ENSG00000163931 | TKT | tumors | 20200485 |
| ENSG00000163931 | TKT | tumor | 20228846 |
| ENSG00000163931 | TKT | endometrial cancer | 20592357 |
| ENSG00000163931 | TKT | malignant tumors | 20596653 |
| ENSG00000163931 | TKT | pancreatic cancer | 20647326 |
| ENSG00000163931 | TKT | tumor | 20975997 |
| ENSG00000163931 | TKT | tumor | 21445778 |
| ENSG00000163931 | TKT | rectal cancer | 21854597 |
| ENSG00000163931 | TKT | Colorectal Cancer | 21980427 |
| ENSG00000163931 | TKT | non-small cell lung cancers | 22027741 |
| ENSG00000163931 | TKT | cancers | 22110952 |
| ENSG00000163931 | TKT | tumour | 22323845 |
| ENSG00000163931 | TKT | tumors | 22658715 |
| ENSG00000163931 | TKT | tumor | 22803947 |
| ENSG00000163931 | TKT | tumor | 23118983 |
| ENSG00000163931 | TKT | tumor | 23261987 |
| ENSG00000163931 | TKT | pancreatic cancer | 23890079 |
| ENSG00000163931 | TKT | cancer | 23893925 |
| ENSG00000163931 | TKT | colorectal cancer | 24193262 |
| ENSG00000163931 | TKT | tumours | 24390277 |
| ENSG00000163931 | TKT | oral cancer | 24666435 |
| ENSG00000163931 | TKT | ovarian cancer | 24694173 |
| ENSG00000163931 | TKT | cancer | 25188286 |
| ENSG00000163931 | TKT | bladder cancer | 25572961 |
| ENSG00000163931 | TKT | cancers | 25859558 |
| ENSG00000163931 | TKT | ovarian cancer | 25895698 |
| ENSG00000163931 | TKT | tumor | 25945836 |
| ENSG00000163931 | TKT | tumors | 26032094 |
| ENSG00000163931 | TKT | tumor | 26153867 |
| ENSG00000163931 | TKT | tumor | 26179749 |
| ENSG00000163931 | TKT | cancer | 26187043 |
| ENSG00000163931 | TKT | gastric cancer | 26406948 |
| ENSG00000163931 | TKT | cancer | 26481897 |
| ENSG00000163931 | TKT | cancer | 26811478 |
| ENSG00000163931 | TKT | tumor | 26861291 |
| ENSG00000163931 | TKT | tumour | 26870251 |
| ENSG00000163931 | TKT | tumor | 26875085 |
| ENSG00000163931 | TKT | tumor | 27391434 |
| ENSG00000163931 | TKT | Esophageal Cancer | 27698919 |
| ENSG00000163931 | TKT | cancer | 27729989 |
| ENSG00000163931 | TKT | cervical cancer | 27904781 |
| ENSG00000163931 | TKT | tumor | 28143530 |
| ENSG00000163931 | TKT | prostate cancer | 28726251 |
| ENSG00000163931 | TKT | tumor | 28746790 |
| ENSG00000163931 | TKT | lung cancer | 29113225 |
| ENSG00000163931 | TKT | cancer | 29208764 |
| ENSG00000163931 | TKT | cancer | 29271183 |
| ENSG00000163931 | TKT | breast cancer | 29290982 |
| ENSG00000163931 | TKT | anaplastic thyroid cancer | 29502067 |
| ENSG00000163931 | TKT | Breast Cancer | 29599405 |
| ENSG00000163931 | TKT | cancer | 29657327 |
| ENSG00000163931 | TKT | prostate cancer | 30119993 |
| ENSG00000163931 | TKT | cancer | 30646877 |
| ENSG00000163931 | TKT | cancer | 30828330 |
| ENSG00000163931 | TKT | tumor | 31154896 |
| ENSG00000163931 | TKT | lung cancer | 31370342 |
| ENSG00000163931 | TKT | thyroid cancer | 31563469 |
| ENSG00000163931 | TKT | ovarian cancer | 31611995 |
| ENSG00000163931 | TKT | cancer | 31949131 |
| ENSG00000163931 | TKT | tumour | 3582243 |
| ENSG00000163931 | TKT | tumor | 454718 |
| ENSG00000163931 | TKT | cancer | 4838352 |
| ENSG00000163931 | TKT | tumour | 519004 |
| ENSG00000163931 | TKT | tumour | 5806393 |
| ENSG00000163931 | TKT | tumor | 6127634 |
| ENSG00000163931 | TKT | tumors | 645360 |
| ENSG00000163931 | TKT | cancer of stomach | 6649520 |
| ENSG00000163931 | TKT | tumors | 6836965 |
| ENSG00000163931 | TKT | adrenocortical tumor | 8617775 |
| ENSG00000163931 | TKT | tumors | 9112646 |
| ENSG00000163931 | TKT | tumor | 9331084 |
| ENSG00000163931 | TKT | cancer | 9488183 |
| ENSG00000163931 | TKT | cancer | 9568183 |
| Ensembl ID | Gene symbol | Disease/phenotype | Mutation type | Mutated / Total samples | Literature |
|---|
| Ensembl ID | Gene symbol | Cancer | P-value | Which worse | show |
|---|---|---|---|---|---|
| ENSG00000163931 | TKT | MESO | 0.00039 | high | |
| ENSG00000163931 | TKT | CHOL | 0.023 | high | |
| ENSG00000163931 | TKT | UVM | 0.00017 | low | |
| ENSG00000163931 | TKT | PAAD | 0.0026 | high | |
| ENSG00000163931 | TKT | UCEC | 0.023 | low | |
| ENSG00000163931 | TKT | ACC | 0.011 | high | |
| ENSG00000163931 | TKT | LGG | 0.00067 | low | |
| ENSG00000163931 | TKT | LUSC | 0.045 | low | |
| ENSG00000163931 | TKT | HNSC | 0.00025 | high | |
| ENSG00000163931 | TKT | READ | 0.0021 | low | |
| ENSG00000163931 | TKT | KIRP | 0.00049 | high | |
| ENSG00000163931 | TKT | KICH | 0.0013 | high | |
| ENSG00000163931 | TKT | THYM | 0.0038 | low | |
| ENSG00000163931 | TKT | COAD | 0.036 | low | |
| ENSG00000163931 | TKT | OV | 0.045 | low | |
| ENSG00000163931 | TKT | KIRC | 0.0018 | high | |
| ENSG00000163931 | TKT | PRAD | 0.019 | high | |
| ENSG00000163931 | TKT | BLCA | 0.0017 | high | |
| ENSG00000163931 | TKT | SKCM | 0.019 | high | |
| ENSG00000163931 | TKT | CESC | 0.039 | high |
| Ensembl ID | Gene symbol | Cancer | CNV type | -log10(q-value) | G-score | average amplitude | frequency |
|---|---|---|---|---|---|---|---|
| ENSG00000163931 | TKT | CHOL | Del | 0.614465 | 0.195478 | 0.624765 | 0.805556 |
| ENSG00000163931 | TKT | LUSC | Del | 4.939862 | 0.112587 | 0.416583 | 0.866267 |
| ENSG00000163931 | TKT | LUAD | Del | 0.972199 | 0.055182 | 0.322459 | 0.465116 |
| ENSG00000163931 | TKT | LGG | Del | 1.890208 | 0.051283 | 0.504357 | 0.095517 |
| ENSG00000163931 | TKT | CESC | Del | 0.910601 | 0.071565 | 0.537829 | 0.416949 |
| ENSG00000163931 | TKT | COAD | Del | 1.829786 | 0.054493 | 0.433292 | 0.159645 |
| ENSG00000163931 | TKT | UCS | Del | 2.652479 | 0.349928 | 0.533254 | 0.625000 |
| ENSG00000163931 | TKT | SARC | Del | 1.490509 | 0.144494 | 0.510907 | 0.245136 |
| ENSG00000163931 | TKT | ESCA | Del | 1.733403 | 0.125917 | 0.444090 | 0.679348 |
| ENSG00000163931 | TKT | HNSC | Del | 1.213032 | 0.060355 | 0.436604 | 0.718391 |
| ENSG00000163931 | TKT | BLCA | Del | 6.452625 | 0.148068 | 0.419413 | 0.291667 |
| ENSG00000163931 | TKT | BRCA | Del | 26.472562 | 0.167209 | 0.462491 | 0.312963 |
| ENSG00000163931 | TKT | STAD | Del | 5.131917 | 0.109492 | 0.346897 | 0.340136 |
| ENSG00000163931 | TKT | UCEC | Del | 2.919112 | 0.071909 | 0.504646 | 0.128015 |
| ENSG00000163931 | TKT | MESO | Del | 17.034324 | 0.541325 | 0.578065 | 0.505747 |
| ENSG00000163931 | TKT | KIRC | Del | 40.250347 | 0.152965 | 0.514801 | 0.861742 |
| ENSG00000163931 | TKT | UVM | Del | 0.821747 | 0.060899 | 0.803024 | 0.550000 |
| ENSG00000163931 | TKT | OV | Del | 1.815722 | 0.199140 | 0.504746 | 0.324698 |