Ensembl ID ENSG00000163931 Gene ID 7086 Accession 11834
Gene Symbol TKT Alias TK;TKT1;SDDHD;HEL107;HEL-S-48 Full Name transketolase
Position 3 : 53224712 - 53256022 Length 31311 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a thiamine-dependent enzyme which plays a role in the channeling of excess sugar phosphates to glycolysis in the pentose phosphate pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012]

ENSG00000163931 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000163931 1.10 8.48e-28 COAD
ENSG00000163931 1.02 1.34e-14 KICH
ENSG00000163931 1.35 6.83e-12 READ
ENSG00000163931 1.50 6.74e-19 KIRP
ENSG00000163931 1.49 1.18e-18 LIHC
ENSG00000163931 1.55 4.60e-26 UCEC
ENSG00000163931 0.75 4.74e-12 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000163931 tumor 10080
ENSG00000163931 cancer 10452541
ENSG00000163931 tumor 10890024
ENSG00000163931 tumor 10928186
ENSG00000163931 tumour 11488910
ENSG00000163931 tumors 13766147
ENSG00000163931 tumor 1492388
ENSG00000163931 tumor 14969819
ENSG00000163931 tumor 15296642
ENSG00000163931 cancer 15991799
ENSG00000163931 cancer 16116031
ENSG00000163931 cancer 16465194
ENSG00000163931 gastric cancer 16969476
ENSG00000163931 ovarian cancer 17291239
ENSG00000163931 tumor 17321041
ENSG00000163931 breast cancer 17342325
ENSG00000163931 colon cancer 17351395
ENSG00000163931 tumor 17970065
ENSG00000163931 cancer 18083562
ENSG00000163931 tumor 18182286
ENSG00000163931 tumors 18267359
ENSG00000163931 tumor 18296915
ENSG00000163931 tumor 18302154
ENSG00000163931 tumor 18394773
ENSG00000163931 tumours 18447912
ENSG00000163931 cancers 18615628
ENSG00000163931 tumors 18700018
ENSG00000163931 cancer 19111488
ENSG00000163931 tumour 19139037
ENSG00000163931 colon cancer 19253370
ENSG00000163931 lung cancer 19294702
ENSG00000163931 uterine cervix cancer 19331662
ENSG00000163931 cancer 19465749
ENSG00000163931 tumors 19545368
ENSG00000163931 cancers 19812737
ENSG00000163931 cancer 20035555
ENSG00000163931 tumors 20200485
ENSG00000163931 tumor 20228846
ENSG00000163931 endometrial cancer 20592357
ENSG00000163931 malignant tumors 20596653
ENSG00000163931 pancreatic cancer 20647326
ENSG00000163931 tumor 20975997
ENSG00000163931 tumor 21445778
ENSG00000163931 rectal cancer 21854597
ENSG00000163931 Colorectal Cancer 21980427
ENSG00000163931 non-small cell lung cancers 22027741
ENSG00000163931 cancers 22110952
ENSG00000163931 tumour 22323845
ENSG00000163931 tumors 22658715
ENSG00000163931 tumor 22803947
ENSG00000163931 tumor 23118983
ENSG00000163931 tumor 23261987
ENSG00000163931 pancreatic cancer 23890079
ENSG00000163931 cancer 23893925
ENSG00000163931 colorectal cancer 24193262
ENSG00000163931 tumours 24390277
ENSG00000163931 oral cancer 24666435
ENSG00000163931 ovarian cancer 24694173
ENSG00000163931 cancer 25188286
ENSG00000163931 bladder cancer 25572961
ENSG00000163931 cancers 25859558
ENSG00000163931 ovarian cancer 25895698
ENSG00000163931 tumor 25945836
ENSG00000163931 tumors 26032094
ENSG00000163931 tumor 26153867
ENSG00000163931 tumor 26179749
ENSG00000163931 cancer 26187043
ENSG00000163931 gastric cancer 26406948
ENSG00000163931 cancer 26481897
ENSG00000163931 cancer 26811478
ENSG00000163931 tumor 26861291
ENSG00000163931 tumour 26870251
ENSG00000163931 tumor 26875085
ENSG00000163931 tumor 27391434
ENSG00000163931 Esophageal Cancer 27698919
ENSG00000163931 cancer 27729989
ENSG00000163931 cervical cancer 27904781
ENSG00000163931 tumor 28143530
ENSG00000163931 prostate cancer 28726251
ENSG00000163931 tumor 28746790
ENSG00000163931 lung cancer 29113225
ENSG00000163931 cancer 29208764
ENSG00000163931 cancer 29271183
ENSG00000163931 breast cancer 29290982
ENSG00000163931 anaplastic thyroid cancer 29502067
ENSG00000163931 Breast Cancer 29599405
ENSG00000163931 cancer 29657327
ENSG00000163931 prostate cancer 30119993
ENSG00000163931 cancer 30646877
ENSG00000163931 cancer 30828330
ENSG00000163931 tumor 31154896
ENSG00000163931 lung cancer 31370342
ENSG00000163931 thyroid cancer 31563469
ENSG00000163931 ovarian cancer 31611995
ENSG00000163931 cancer 31949131
ENSG00000163931 tumour 3582243
ENSG00000163931 tumor 454718
ENSG00000163931 cancer 4838352
ENSG00000163931 tumour 519004
ENSG00000163931 tumour 5806393
ENSG00000163931 tumor 6127634
ENSG00000163931 tumors 645360
ENSG00000163931 cancer of stomach 6649520
ENSG00000163931 tumors 6836965
ENSG00000163931 adrenocortical tumor 8617775
ENSG00000163931 tumors 9112646
ENSG00000163931 tumor 9331084
ENSG00000163931 cancer 9488183
ENSG00000163931 cancer 9568183
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000163931 MESO 0.00039 high
ENSG00000163931 CHOL 0.023 high
ENSG00000163931 UVM 0.00017 low
ENSG00000163931 PAAD 0.0026 high
ENSG00000163931 UCEC 0.023 low
ENSG00000163931 ACC 0.011 high
ENSG00000163931 LGG 0.00067 low
ENSG00000163931 LUSC 0.045 low
ENSG00000163931 HNSC 0.00025 high
ENSG00000163931 READ 0.0021 low
ENSG00000163931 KIRP 0.00049 high
ENSG00000163931 KICH 0.0013 high
ENSG00000163931 THYM 0.0038 low
ENSG00000163931 COAD 0.036 low
ENSG00000163931 OV 0.045 low
ENSG00000163931 KIRC 0.0018 high
ENSG00000163931 PRAD 0.019 high
ENSG00000163931 BLCA 0.0017 high
ENSG00000163931 SKCM 0.019 high
ENSG00000163931 CESC 0.039 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000163931 CHOL Del 0.614465 0.195478 0.624765 0.805556
ENSG00000163931 LUSC Del 4.939862 0.112587 0.416583 0.866267
ENSG00000163931 LUAD Del 0.972199 0.055182 0.322459 0.465116
ENSG00000163931 LGG Del 1.890208 0.051283 0.504357 0.095517
ENSG00000163931 CESC Del 0.910601 0.071565 0.537829 0.416949
ENSG00000163931 COAD Del 1.829786 0.054493 0.433292 0.159645
ENSG00000163931 UCS Del 2.652479 0.349928 0.533254 0.625000
ENSG00000163931 SARC Del 1.490509 0.144494 0.510907 0.245136
ENSG00000163931 ESCA Del 1.733403 0.125917 0.444090 0.679348
ENSG00000163931 HNSC Del 1.213032 0.060355 0.436604 0.718391
ENSG00000163931 BLCA Del 6.452625 0.148068 0.419413 0.291667
ENSG00000163931 BRCA Del 26.472562 0.167209 0.462491 0.312963
ENSG00000163931 STAD Del 5.131917 0.109492 0.346897 0.340136
ENSG00000163931 UCEC Del 2.919112 0.071909 0.504646 0.128015
ENSG00000163931 MESO Del 17.034324 0.541325 0.578065 0.505747
ENSG00000163931 KIRC Del 40.250347 0.152965 0.514801 0.861742
ENSG00000163931 UVM Del 0.821747 0.060899 0.803024 0.550000
ENSG00000163931 OV Del 1.815722 0.199140 0.504746 0.324698