Ensembl ID ENSG00000163902 Gene ID 6184 Accession 10381
Gene Symbol RPN1 Alias OST1;RBPH1 Full Name ribophorin I
Position 3 : 128619969 - 128681075 Length 61107 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein forms part of the regulatory subunit of the 26S proteasome and may mediate binding of ubiquitin-like domains to this proteasome. [provided by RefSeq, Jul 2008]

ENSG00000163902 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000163902 0.66 6.78e-23 HNSC
ENSG00000163902 0.86 1.58e-14 BLCA
ENSG00000163902 0.75 9.50e-48 BRCA
ENSG00000163902 0.63 1.82e-16 LUSC
ENSG00000163902 0.86 3.97e-25 UCEC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000163902 AML 14607750
ENSG00000163902 AML with recurrent genetic abnormalities 19860179
ENSG00000163902 non-small cell lung cancers 20193080
ENSG00000163902 tumor 21408220
ENSG00000163902 tumor 21602888
ENSG00000163902 kidney cancer 21634111
ENSG00000163902 pancreatic tumor 24471499
ENSG00000163902 AML 25794001
ENSG00000163902 AML 26237023
ENSG00000163902 bladder cancer 27034531
ENSG00000163902 cancer 27171286
ENSG00000163902 AML 27542247
ENSG00000163902 AML without maturation 28977979
ENSG00000163902 cancer 30881377
ENSG00000163902 esophageal cancer 30940778
ENSG00000163902 AMLs 9192861
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
ENSG00000163902 colon adenocarcinoma sequence_alteration 0.9695% (7/722) 1 entry
ENSG00000163902 chronic lymphocytic leukemia sequence_alteration 0.3378% (3/888) 1 entry
ENSG00000163902 brain glioblastoma sequence_alteration 0.216% (2/926) 1 entry
ENSG00000163902 skin melanoma missense_variant 0.9307% (9/967) 2 entries
ENSG00000163902 embryonal rhabdomyosarcoma missense_variant 2.632% (2/76) 1 entry
ENSG00000163902 prostate carcinoma sequence_alteration 1.405% (6/427) 1 entry
ENSG00000163902 esophageal squamous cell carcinoma sequence_alteration 0.5926% (4/675) 2 entries
ENSG00000163902 skin melanoma sequence_alteration 0.9307% (9/967) 1 entry
ENSG00000163902 colon adenocarcinoma missense_variant 0.9695% (7/722) 3 entries
ENSG00000163902 clear cell renal carcinoma sequence_alteration 0.4354% (6/1378) 2 entries
ENSG00000163902 embryonal rhabdomyosarcoma sequence_alteration 2.632% (2/76) 1 entry
ENSG00000163902 clear cell renal carcinoma missense_variant 0.4354% (6/1378) 2 entries
ENSG00000163902 female breast carcinoma sequence_alteration 0.7491% (2/267) 1 entry
ENSG00000163902 esophageal squamous cell carcinoma missense_variant 0.5926% (4/675) 3 entries
ENSG00000163902 colorectal adenocarcinoma sequence_alteration 2.197% (25/1138) 2 entries
ENSG00000163902 colorectal adenocarcinoma missense_variant 2.197% (25/1138) 3 entries
ENSG00000163902 lung adenocarcinoma missense_variant 0.5159% (6/1163) 3 entries
ENSG00000163902 colorectal adenocarcinoma frameshift_variant 2.197% (25/1138) 1 entry
ENSG00000163902 gastric adenocarcinoma missense_variant 0.8961% (5/558) 1 entry
ENSG00000163902 colon carcinoma missense_variant 12.5% (1/8) 1 entry
ENSG00000163902 Breast Carcinoma by Gene Expression Profile missense_variant 5.263% (1/19) 1 entry
ENSG00000163902 Brain Stem Glioblastoma sequence_alteration 1.786% (1/56) 1 entry
ENSG00000163902 ovarian serous adenocarcinoma frameshift_variant 0.2972% (2/673) 1 entry
ENSG00000163902 female breast carcinoma missense_variant 0.7491% (2/267) 1 entry
ENSG00000163902 neoplasm frameshift_variant 3.571% (1/28) 1 entry
ENSG00000163902 Mantle cell lymphoma missense_variant 2.439% (1/41) 1 entry
ENSG00000163902 prostate carcinoma missense_variant 1.405% (6/427) 1 entry
ENSG00000163902 rectal adenocarcinoma sequence_alteration 0.4525% (1/221) 1 entry
ENSG00000163902 non-small cell lung carcinoma sequence_alteration 1.887% (1/53) 1 entry
ENSG00000163902 melanoma missense_variant 0.9901% (1/101) 1 entry
ENSG00000163902 basal cell carcinoma missense_variant 1.724% (1/58) 1 entry
ENSG00000163902 Gallbladder Adenocarcinoma sequence_alteration 1.149% (1/87) 1 entry
ENSG00000163902 rectal adenocarcinoma missense_variant 0.4525% (1/221) 1 entry
ENSG00000163902 osteosarcoma sequence_alteration 0.8621% (1/116) 1 entry
ENSG00000163902 Merkel cell skin cancer missense_variant 3.333% (1/30) 1 entry
ENSG00000163902 diffuse gastric adenocarcinoma missense_variant 1.266% (1/79) 1 entry
ENSG00000163902 adenosquamous lung carcinoma missense_variant 9.091% (1/11) 1 entry
ENSG00000163902 non-small cell lung carcinoma missense_variant 1.887% (1/53) 1 entry
ENSG00000163902 hepatocellular carcinoma missense_variant 1.001% (9/899) 1 entry
ENSG00000163902 ovarian serous adenocarcinoma missense_variant 0.2972% (2/673) 1 entry
ENSG00000163902 Gallbladder Adenocarcinoma missense_variant 1.149% (1/87) 1 entry
ENSG00000163902 metaplastic breast carcinoma missense_variant 1.961% (1/51) 1 entry
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000163902 MESO 0.012 high
ENSG00000163902 SARC 0.0083 high
ENSG00000163902 UVM 0.047 low
ENSG00000163902 PAAD 0.0055 high
ENSG00000163902 ACC 0.0017 high
ENSG00000163902 HNSC 0.017 high
ENSG00000163902 KIRP 0.015 high
ENSG00000163902 KICH 0.016 high
ENSG00000163902 THYM 0.0097 low
ENSG00000163902 BRCA 0.02 low
ENSG00000163902 COAD 0.013 high
ENSG00000163902 ESCA 0.0016 high
ENSG00000163902 OV 0.022 low
ENSG00000163902 TGCT 0.015 high
ENSG00000163902 LAML 0.04 low
ENSG00000163902 GBM 0.033 high
ENSG00000163902 SKCM 0.039 low
ENSG00000163902 CESC 0.043 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000163902 GBM Del 1.151254 0.057791 0.493485 0.093588
ENSG00000163902 PRAD Amp 3.827518 0.088768 0.475201 0.152439