Ensembl ID ENSG00000163541 Gene ID 8802 Accession 11449
Gene Symbol SUCLG1 Alias GALPHA;MTDPS9;SUCLA1 Full Name succinate-CoA ligase GDP/ADP-forming subunit alpha
Position 2 : 84423528 - 84459285 Length 35758 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. This enzyme is targeted to the mitochondria and catalyzes the conversion of succinyl CoA and ADP or GDP to succinate and ATP or GTP. Mutations in this gene are the cause of the metabolic disorder fatal infantile lactic acidosis and mitochondrial DNA depletion. [provided by RefSeq, Feb 2010]

ENSG00000163541 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000163541 SUCLG1 -1.7 5.29e-86 KIRC
ENSG00000163541 SUCLG1 -0.6 5.32e-16 HNSC
ENSG00000163541 SUCLG1 -0.5 1.10e-38 BRCA
ENSG00000163541 SUCLG1 -0.7 9.27e-15 COAD
ENSG00000163541 SUCLG1 -0.9 3.37e-16 STAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000163541 SUCLG1 GBM 28035070
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000163541 SUCLG1 MESO 0.0046 low
ENSG00000163541 SUCLG1 STAD 0.025 high
ENSG00000163541 SUCLG1 PAAD 0.019 low
ENSG00000163541 SUCLG1 UCEC 2e-04 high
ENSG00000163541 SUCLG1 THCA 0.019 low
ENSG00000163541 SUCLG1 READ 0.01 low
ENSG00000163541 SUCLG1 KIRP 0.012 low
ENSG00000163541 SUCLG1 KICH 0.042 high
ENSG00000163541 SUCLG1 PCPG 0.00043 high
ENSG00000163541 SUCLG1 BRCA 0.0076 high
ENSG00000163541 SUCLG1 COAD 0.032 low
ENSG00000163541 SUCLG1 ESCA 0.013 high
ENSG00000163541 SUCLG1 KIRC 0.0063 low
ENSG00000163541 SUCLG1 LAML 0.00041 high
ENSG00000163541 SUCLG1 CESC 0.0046 low
ENSG00000163541 SUCLG1 LIHC 0.016 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency