Ensembl ID ENSG00000163468 Gene ID 7203 Accession 1616
Gene Symbol CCT3 Alias CCTG;PIG48;TRIC5;CCT-gamma;TCP-1-gamma Full Name chaperonin containing TCP1 subunit 3
Position 1 : 156308968 - 156367873 Length 58906 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants have been characterized for this gene. In addition, a pseudogene of this gene has been found on chromosome 8. [provided by RefSeq, Aug 2010]

ENSG00000163468 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000163468 CCT3 1.21 2.13e-100 BRCA
ENSG00000163468 CCT3 0.94 8.35e-36 COAD
ENSG00000163468 CCT3 0.97 2.94e-13 READ
ENSG00000163468 CCT3 1.36 3.94e-76 LUSC
ENSG00000163468 CCT3 0.51 2.83e-15 PRAD
ENSG00000163468 CCT3 1.15 2.82e-34 LIHC
ENSG00000163468 CCT3 0.91 6.68e-24 UCEC
ENSG00000163468 CCT3 1.34 8.71e-51 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000163468 CCT3 liver tumors 12079511
ENSG00000163468 CCT3 tumors 12586295
ENSG00000163468 CCT3 ovarian cancer 16030107
ENSG00000163468 CCT3 cancer 26229401
ENSG00000163468 CCT3 cancer 26739059
ENSG00000163468 CCT3 tumor 27390551
ENSG00000163468 CCT3 Non-Small Cell Lung Cancer 27827316
ENSG00000163468 CCT3 Gastric Cancer 28337660
ENSG00000163468 CCT3 breast cancer 28379421
ENSG00000163468 CCT3 breast cancer 28447237
ENSG00000163468 CCT3 breast cancer 28484925
ENSG00000163468 CCT3 Cancer 29097500
ENSG00000163468 CCT3 breast cancer 29274617
ENSG00000163468 CCT3 gastric cancer 29340068
ENSG00000163468 CCT3 prostate cancer 29487723
ENSG00000163468 CCT3 cancer 29805652
ENSG00000163468 CCT3 tumours 29954368
ENSG00000163468 CCT3 metastatic colorectal cancer 30318772
ENSG00000163468 CCT3 Cancer 30473171
ENSG00000163468 CCT3 tumor 30506376
ENSG00000163468 CCT3 Cancer 31143848
ENSG00000163468 CCT3 tumor 31406247
ENSG00000163468 CCT3 liver cancer 31501420
ENSG00000163468 CCT3 breast cancer 31675993
ENSG00000163468 CCT3 tumor 31934176
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000163468 CCT3 MESO 0.0016 high
ENSG00000163468 CCT3 SARC 0.046 high
ENSG00000163468 CCT3 UVM 0.0016 high
ENSG00000163468 CCT3 UCEC 0.0038 low
ENSG00000163468 CCT3 THCA 0.014 low
ENSG00000163468 CCT3 HNSC 0.0045 high
ENSG00000163468 CCT3 KICH 0.0084 high
ENSG00000163468 CCT3 LUAD 0.00018 high
ENSG00000163468 CCT3 PCPG 0.02 high
ENSG00000163468 CCT3 THYM 0.028 low
ENSG00000163468 CCT3 BRCA 0.019 high
ENSG00000163468 CCT3 COAD 0.049 high
ENSG00000163468 CCT3 ESCA 0.0016 high
ENSG00000163468 CCT3 KIRC 0.012 high
ENSG00000163468 CCT3 TGCT 0.049 high
ENSG00000163468 CCT3 LAML 0.0026 high
ENSG00000163468 CCT3 GBM 0.0067 low
ENSG00000163468 CCT3 SKCM 0.00076 high
ENSG00000163468 CCT3 CESC 0.0053 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000163468 CCT3 CHOL Amp 0.963900 0.479130 0.983432 0.638889
ENSG00000163468 CCT3 LUSC Amp 1.989044 0.235242 0.527242 0.520958
ENSG00000163468 CCT3 LUAD Amp 15.281065 0.342347 0.583033 0.732558
ENSG00000163468 CCT3 LGG Amp 1.091718 0.049842 0.555098 0.079922
ENSG00000163468 CCT3 CESC Amp 2.589271 0.198297 0.615414 0.545763
ENSG00000163468 CCT3 UCS Amp 1.297809 0.591478 0.795575 0.678571
ENSG00000163468 CCT3 SARC Amp 2.482597 0.351087 0.683374 0.361868
ENSG00000163468 CCT3 GBM Amp 1.244069 0.077916 0.538417 0.181976
ENSG00000163468 CCT3 ESCA Amp 0.617135 0.252871 0.493906 0.483696
ENSG00000163468 CCT3 SKCM Amp 2.671264 0.180349 0.679776 0.544959
ENSG00000163468 CCT3 LIHC Amp 16.430998 0.375836 0.896722 0.751351
ENSG00000163468 CCT3 PCPG Amp 0.826699 0.073017 0.648739 0.160494
ENSG00000163468 CCT3 DLBC Amp 1.852987 0.292853 0.670338 0.270833
ENSG00000163468 CCT3 BLCA Amp 7.063342 0.333330 0.559554 0.446078
ENSG00000163468 CCT3 BRCA Amp 17.227242 0.327670 0.779935 0.725000
ENSG00000163468 CCT3 STAD Amp 1.162098 0.146196 0.440894 0.358277
ENSG00000163468 CCT3 UCEC Amp 13.298165 0.283571 0.887266 0.465677
ENSG00000163468 CCT3 OV Amp 9.246972 0.533836 0.718879 0.606218