Ensembl ID ENSG00000162775 Gene ID 64783 Accession 14959
Gene Symbol RBM15 Alias OTT;OTT1;SPEN Full Name RNA binding motif protein 15
Position 1 : 110338506 - 110346681 Length 8176 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary Members of the SPEN (Split-end) family of proteins, including RBM15, have repressor function in several signaling pathways and may bind to RNA through interaction with spliceosome components (Hiriart et al., 2005 [PubMed 16129689]).[supplied by OMIM, Feb 2009]

ENSG00000162775 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000162775 RBM15 AML-M7 11746984
ENSG00000162775 RBM15 tumors 1180813
ENSG00000162775 RBM15 tumours 15848906
ENSG00000162775 RBM15 AML with recurrent genetic abnormalities 19860179
ENSG00000162775 RBM15 cervical cancer 21157538
ENSG00000162775 RBM15 HNSCC 22920680
ENSG00000162775 RBM15 tumor 24023357
ENSG00000162775 RBM15 Cancer 25401087
ENSG00000162775 RBM15 AML 25794001
ENSG00000162775 RBM15 tumours 2586719
ENSG00000162775 RBM15 head and neck cancer 27030990
ENSG00000162775 RBM15 cervical cancer 27416796
ENSG00000162775 RBM15 breast cancer 27533254
ENSG00000162775 RBM15 prostate cancer 27890566
ENSG00000162775 RBM15 cancers 28081722
ENSG00000162775 RBM15 AML 28154779
ENSG00000162775 RBM15 tumor 282641
ENSG00000162775 RBM15 tumors 286302
ENSG00000162775 RBM15 cancer 28898958
ENSG00000162775 RBM15 AML with minimal differentiation 28977979
ENSG00000162775 RBM15 cervical cancer 29156713
ENSG00000162775 RBM15 phyllodes tumours 29315289
ENSG00000162775 RBM15 Wilms tumor 29374143
ENSG00000162775 RBM15 Wilms’ tumor 29709557
ENSG00000162775 RBM15 Cancer 29961174
ENSG00000162775 RBM15 AML 30096915
ENSG00000162775 RBM15 Cancer 30736809
ENSG00000162775 RBM15 AML 31024852
ENSG00000162775 RBM15 ovarian cancer 31312099
ENSG00000162775 RBM15 tumour 31574418
ENSG00000162775 RBM15 gastric cancer 31681576
ENSG00000162775 RBM15 cancer 31720080
ENSG00000162775 RBM15 tumor 31892592
ENSG00000162775 RBM15 tumors 333858
ENSG00000162775 RBM15 tumor 6126948
ENSG00000162775 RBM15 tumours 6873524
ENSG00000162775 RBM15 tumor 7269228
ENSG00000162775 RBM15 tumor 987856
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
ENSG00000162775 RBM15 colon adenocarcinoma frameshift_variant 2.078% (15/722) 3 entries
ENSG00000162775 RBM15 melanoma missense_variant 6.863% (7/102) 2 entries
ENSG00000162775 RBM15 cecum adenocarcinoma missense_variant 2.4% (3/125) 1 entry
ENSG00000162775 RBM15 prostate adenocarcinoma missense_variant 0.619% (9/1454) 1 entry
ENSG00000162775 RBM15 head and neck squamous cell carcinoma sequence_alteration 0.4021% (3/746) 1 entry
ENSG00000162775 RBM15 skin melanoma missense_variant 0.9307% (9/967) 2 entries
ENSG00000162775 RBM15 colorectal adenocarcinoma missense_variant 2.724% (31/1138) 2 entries
ENSG00000162775 RBM15 colorectal adenocarcinoma frameshift_variant 2.724% (31/1138) 2 entries
ENSG00000162775 RBM15 papillary renal cell carcinoma missense_variant 1.194% (4/335) 1 entry
ENSG00000162775 RBM15 hepatocellular carcinoma missense_variant 0.4444% (4/900) 1 entry
ENSG00000162775 RBM15 lung adenocarcinoma sequence_alteration 1.802% (22/1221) 2 entries
ENSG00000162775 RBM15 colon adenocarcinoma missense_variant 2.078% (15/722) 3 entries
ENSG00000162775 RBM15 bile duct adenocarcinoma missense_variant 1.058% (2/189) 2 entries
ENSG00000162775 RBM15 colorectal adenocarcinoma sequence_alteration 2.724% (31/1138) 1 entry
ENSG00000162775 RBM15 oral squamous cell carcinoma missense_variant 0.9709% (2/206) 2 entries
ENSG00000162775 RBM15 lung adenocarcinoma stop_gained 1.802% (22/1221) 1 entry
ENSG00000162775 RBM15 esophageal squamous cell carcinoma missense_variant 0.4444% (3/675) 2 entries
ENSG00000162775 RBM15 rectal adenocarcinoma missense_variant 2.262% (5/221) 2 entries
ENSG00000162775 RBM15 ovarian serous adenocarcinoma missense_variant 1.04% (7/673) 2 entries
ENSG00000162775 RBM15 small cell lung carcinoma missense_variant 0.9259% (3/324) 2 entries
ENSG00000162775 RBM15 prostate adenocarcinoma sequence_alteration 0.619% (9/1454) 1 entry
ENSG00000162775 RBM15 squamous cell lung carcinoma missense_variant 0.3636% (3/825) 2 entries
ENSG00000162775 RBM15 rectal adenocarcinoma stop_gained 2.262% (5/221) 1 entry
ENSG00000162775 RBM15 lung adenocarcinoma missense_variant 1.802% (22/1221) 4 entries
ENSG00000162775 RBM15 pancreatic ductal adenocarcinoma missense_variant 0.4766% (6/1259) 2 entries
ENSG00000162775 RBM15 clear cell renal carcinoma missense_variant 0.3626% (5/1379) 1 entry
ENSG00000162775 RBM15 anaplastic oligodendroglioma frameshift_variant 2.381% (1/42) 1 entry
ENSG00000162775 RBM15 female breast carcinoma stop_gained 0.2558% (1/391) 1 entry
ENSG00000162775 RBM15 colon adenocarcinoma stop_gained 2.078% (15/722) 1 entry
ENSG00000162775 RBM15 Invasive Breast Carcinoma missense_variant 2.174% (1/46) 1 entry
ENSG00000162775 RBM15 skin melanoma sequence_alteration 0.9307% (9/967) 1 entry
ENSG00000162775 RBM15 melanoma sequence_alteration 6.863% (7/102) 1 entry
ENSG00000162775 RBM15 gastric intestinal type adenocarcinoma missense_variant 1.176% (1/85) 1 entry
ENSG00000162775 RBM15 prostate adenocarcinoma frameshift_variant 0.619% (9/1454) 1 entry
ENSG00000162775 RBM15 diffuse large B-cell lymphoma frameshift_variant 0.33% (1/303) 1 entry
ENSG00000162775 RBM15 prostate carcinoma stop_gained 0.4132% (2/484) 1 entry
ENSG00000162775 RBM15 diffuse gastric adenocarcinoma stop_gained 1.266% (1/79) 1 entry
ENSG00000162775 RBM15 basal cell carcinoma stop_gained 3.448% (2/58) 1 entry
ENSG00000162775 RBM15 colorectal adenocarcinoma stop_gained 2.724% (31/1138) 1 entry
ENSG00000162775 RBM15 diffuse large B-cell lymphoma missense_variant 0.33% (1/303) 1 entry
ENSG00000162775 RBM15 central nervous system primitive neuroectodermal neoplasm missense_variant 0.2212% (1/452) 1 entry
ENSG00000162775 RBM15 pharyngeal squamous cell carcinoma stop_gained 3.226% (1/31) 1 entry
ENSG00000162775 RBM15 ovarian serous adenocarcinoma sequence_alteration 1.04% (7/673) 1 entry
ENSG00000162775 RBM15 esophageal squamous cell carcinoma frameshift_variant 0.4444% (3/675) 1 entry
ENSG00000162775 RBM15 prostate carcinoma sequence_alteration 0.4132% (2/484) 1 entry
ENSG00000162775 RBM15 esophageal adenocarcinoma missense_variant 0.4566% (2/438) 1 entry
ENSG00000162775 RBM15 head and neck squamous cell carcinoma missense_variant 0.4021% (3/746) 1 entry
ENSG00000162775 RBM15 breast phyllodes tumor frameshift_variant 4.545% (1/22) 1 entry
ENSG00000162775 RBM15 basal cell carcinoma missense_variant 3.448% (2/58) 1 entry
ENSG00000162775 RBM15 osteosarcoma sequence_alteration 0.8475% (1/118) 1 entry
ENSG00000162775 RBM15 papillary renal cell carcinoma frameshift_variant 1.194% (4/335) 1 entry
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000162775 RBM15 STAD 0.0017 low
ENSG00000162775 RBM15 CHOL 0.04 low
ENSG00000162775 RBM15 UCEC 0.0079 high
ENSG00000162775 RBM15 THCA 0.016 high
ENSG00000162775 RBM15 HNSC 0.013 low
ENSG00000162775 RBM15 READ 0.0072 low
ENSG00000162775 RBM15 KIRP 0.00061 high
ENSG00000162775 RBM15 KICH 0.031 high
ENSG00000162775 RBM15 LUAD 0.018 high
ENSG00000162775 RBM15 PCPG 0.026 high
ENSG00000162775 RBM15 THYM 0.026 low
ENSG00000162775 RBM15 COAD 0.021 low
ENSG00000162775 RBM15 OV 0.047 low
ENSG00000162775 RBM15 KIRC 0.0072 low
ENSG00000162775 RBM15 PRAD 0.0077 high
ENSG00000162775 RBM15 SKCM 0.012 low
ENSG00000162775 RBM15 LIHC 0.0016 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000162775 RBM15 LUSC Del 8.751153 0.141976 0.395646 0.441118
ENSG00000162775 RBM15 LUAD Del 11.079354 0.133653 0.350183 0.302326
ENSG00000162775 RBM15 CESC Del 1.193658 0.077070 0.417345 0.105085
ENSG00000162775 RBM15 COAD Del 2.964595 0.064815 0.412892 0.272727
ENSG00000162775 RBM15 ESCA Del 1.580943 0.121798 0.391052 0.320652
ENSG00000162775 RBM15 SKCM Del 3.549142 0.106495 0.421877 0.223433
ENSG00000162775 RBM15 HNSC Del 9.887161 0.121124 0.382384 0.229885
ENSG00000162775 RBM15 PCPG Del 17.695750 0.269994 0.695325 0.746914
ENSG00000162775 RBM15 BRCA Del 7.159262 0.102952 0.392327 0.301852
ENSG00000162775 RBM15 STAD Del 1.124847 0.067021 0.350414 0.206349
ENSG00000162775 RBM15 MESO Del 7.994431 0.347195 0.557302 0.390805