Ensembl ID ENSG00000162688 Gene ID 178 Accession 321
Gene Symbol AGL Alias GDE Full Name amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
Position 1 : 99850361 - 99924023 Length 73663 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes the glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in this gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing. Alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

ENSG00000162688 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000162688 -1.0 1.64e-37 KIRC
ENSG00000162688 -1.6 1.37e-44 HNSC
ENSG00000162688 -0.7 2.80e-11 COAD
ENSG00000162688 -1.1 8.03e-11 READ
ENSG00000162688 -0.5 4.65e-11 PRAD
ENSG00000162688 -1.5 7.75e-28 LIHC
ENSG00000162688 -2.6 6.54e-50 CHOL
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000162688 tumor 10799474
ENSG00000162688 cancer 15953573
ENSG00000162688 pancreatic cancer 1691065
ENSG00000162688 tumor 24700805
ENSG00000162688 cancer 25482527
ENSG00000162688 pancreatic cancer 2563574
ENSG00000162688 bladder cancer 26032551
ENSG00000162688 tumor 26490312
ENSG00000162688 Bladder cancer 26553625
ENSG00000162688 tumour 26882899
ENSG00000162688 tumor 26975021
ENSG00000162688 bladder cancer 27595989
ENSG00000162688 bladder cancer 28584628
ENSG00000162688 GBM 29632728
ENSG00000162688 non-small cell lung cancer 29682180
ENSG00000162688 colon cancer 29928385
ENSG00000162688 bladder cancer 30403777
ENSG00000162688 tumor 30443561
ENSG00000162688 tumor 30556699
ENSG00000162688 pancreatic cancer 3362841
ENSG00000162688 tumor 3596003
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000162688 MESO 0.039 low
ENSG00000162688 SARC 0.027 high
ENSG00000162688 STAD 0.035 low
ENSG00000162688 PAAD 0.007 high
ENSG00000162688 UCEC 0.014 high
ENSG00000162688 THCA 0.043 high
ENSG00000162688 LUSC 0.0066 low
ENSG00000162688 HNSC 0.041 low
ENSG00000162688 READ 0.039 low
ENSG00000162688 KIRP 0.022 low
ENSG00000162688 COAD 0.0069 low
ENSG00000162688 ESCA 0.036 high
ENSG00000162688 DLBC 0.026 high
ENSG00000162688 PRAD 0.029 high
ENSG00000162688 BLCA 0.038 high
ENSG00000162688 LAML 0.046 low
ENSG00000162688 GBM 0.00084 low
ENSG00000162688 CESC 0.014 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000162688 LUSC Del 2.872268 0.092922 0.374923 0.419162
ENSG00000162688 LUAD Del 8.701498 0.118126 0.348578 0.290698
ENSG00000162688 CESC Del 0.956313 0.072299 0.432066 0.101695
ENSG00000162688 COAD Del 4.648281 0.078018 0.421672 0.283814
ENSG00000162688 SKCM Del 3.818926 0.109445 0.428762 0.239782
ENSG00000162688 HNSC Del 3.054646 0.077777 0.362047 0.189655
ENSG00000162688 PCPG Del 15.531859 0.246604 0.689993 0.746914
ENSG00000162688 BRCA Del 7.256041 0.103453 0.395898 0.325000
ENSG00000162688 STAD Del 0.938287 0.064075 0.358203 0.204082
ENSG00000162688 MESO Del 9.438052 0.382039 0.575173 0.402299