Ensembl ID ENSG00000162623 Gene ID 127253 Accession 24757
Gene Symbol TYW3 Alias C1orf171 Full Name tRNA-yW synthesizing protein 3 homolog
Position 1 : 74733152 - 74766677 Length 33526 bases Strand Plus strand
Status Confidence Main interacting RNAstRNARBP type Canonical_RBPs
Summary Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW3 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).[supplied by OMIM, Mar 2008]

ENSG00000162623 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000162623 TYW3 -0.4 6.15e-17 KIRC
ENSG00000162623 TYW3 -0.4 4.88e-18 BRCA
ENSG00000162623 TYW3 -0.6 4.48e-13 UCEC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000162623 TYW3 gastric cancer 26863570
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000162623 TYW3 MESO 0.037 low
ENSG00000162623 TYW3 CHOL 0.043 low
ENSG00000162623 TYW3 PAAD 0.034 low
ENSG00000162623 TYW3 UCEC 0.027 low
ENSG00000162623 TYW3 ACC 0.0052 low
ENSG00000162623 TYW3 LGG 0.00011 high
ENSG00000162623 TYW3 READ 0.016 low
ENSG00000162623 TYW3 KICH 0.027 high
ENSG00000162623 TYW3 THYM 0.0072 low
ENSG00000162623 TYW3 BRCA 0.0065 low
ENSG00000162623 TYW3 ESCA 0.026 high
ENSG00000162623 TYW3 BLCA 0.0031 high
ENSG00000162623 TYW3 GBM 0.02 high
ENSG00000162623 TYW3 SKCM 0.00023 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000162623 TYW3 LUAD Del 1.916279 0.066512 0.307242 0.255814
ENSG00000162623 TYW3 COAD Del 5.138082 0.081619 0.420526 0.292683
ENSG00000162623 TYW3 SKCM Del 0.778273 0.067850 0.418679 0.196185
ENSG00000162623 TYW3 HNSC Del 0.742351 0.054755 0.338052 0.174330
ENSG00000162623 TYW3 PCPG Del 10.762276 0.198486 0.684133 0.734568
ENSG00000162623 TYW3 BRCA Del 1.112629 0.067365 0.386517 0.301852
ENSG00000162623 TYW3 MESO Del 2.507062 0.195375 0.557957 0.275862