Ensembl ID ENSG00000161956 Gene ID 26168 Accession 17862
Gene Symbol SENP3 Alias SSP3;Ulp1;SMT3IP1 Full Name SUMO specific peptidase 3
Position 17 : 7561919 - 7571969 Length 10051 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP3, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM, Jun 2009]

ENSG00000161956 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000161956 SENP3 0.55 2.43e-15 LUSC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000161956 SENP3 cancers 20181954
ENSG00000161956 SENP3 cancer 20924358
ENSG00000161956 SENP3 cancer 21152235
ENSG00000161956 SENP3 cancer 23054070
ENSG00000161956 SENP3 tumor 23467634
ENSG00000161956 SENP3 gastric cancer 25216525
ENSG00000161956 SENP3 gastric cancer 26511642
ENSG00000161956 SENP3 epithelial ovarian cancer 26807442
ENSG00000161956 SENP3 head and neck cancer 27181202
ENSG00000161956 SENP3 epithelial ovarian cancer 28351334
ENSG00000161956 SENP3 Cancer 29438989
ENSG00000161956 SENP3 tumor 30089837
ENSG00000161956 SENP3 cancer 31293646
ENSG00000161956 SENP3 AML 31444354
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000161956 SENP3 SARC 0.0013 high
ENSG00000161956 SENP3 CHOL 0.0019 high
ENSG00000161956 SENP3 UVM 0.011 low
ENSG00000161956 SENP3 ACC 0.0065 high
ENSG00000161956 SENP3 LGG 0.005 low
ENSG00000161956 SENP3 LUSC 0.011 low
ENSG00000161956 SENP3 READ 0.039 low
ENSG00000161956 SENP3 KIRP 0.00015 low
ENSG00000161956 SENP3 KICH 0.023 high
ENSG00000161956 SENP3 PCPG 0.019 low
ENSG00000161956 SENP3 BRCA 0.049 low
ENSG00000161956 SENP3 COAD 0.022 high
ENSG00000161956 SENP3 OV 0.02 low
ENSG00000161956 SENP3 DLBC 0.032 high
ENSG00000161956 SENP3 KIRC 0.0014 high
ENSG00000161956 SENP3 PRAD 0.03 high
ENSG00000161956 SENP3 BLCA 0.036 high
ENSG00000161956 SENP3 LAML 0.013 high
ENSG00000161956 SENP3 SKCM 0.0069 high
ENSG00000161956 SENP3 LIHC 0.0011 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000161956 SENP3 SARC Del 18.408539 0.398095 0.598005 0.455253
ENSG00000161956 SENP3 GBM Del 4.319272 0.087250 0.505439 0.164645
ENSG00000161956 SENP3 LIHC Del 9.402392 0.161227 0.662385 0.605405
ENSG00000161956 SENP3 DLBC Del 0.740752 0.126309 0.522682 0.229167
ENSG00000161956 SENP3 BRCA Del 2.016677 0.074683 0.490250 0.609259
ENSG00000161956 SENP3 PRAD Del 29.998545 0.249978 0.553603 0.323171