Ensembl ID ENSG00000161016 Gene ID 6132 Accession 10368
Gene Symbol RPL8 Alias L8;uL2 Full Name ribosomal protein L8
Position 8 : 144789766 - 144792587 Length 2822 bases Strand Minus strand
Status Confidence Main interacting RNAsrRNARBP type Canonical_RBPs
Summary Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L2P family of ribosomal proteins. It is located in the cytoplasm. In rat, the protein associates with the 5.8S rRNA, very likely participates in the binding of aminoacyl-tRNA, and is a constituent of the elongation factor 2-binding site at the ribosomal subunit interface. Alternatively spliced transcript variants encoding the same protein exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

ENSG00000161016 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000161016 RPL8 0.76 1.29e-16 KIRC
ENSG00000161016 RPL8 1.01 1.34e-11 COAD
ENSG00000161016 RPL8 0.80 5.09e-14 LUSC
ENSG00000161016 RPL8 1.15 2.54e-12 LIHC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000161016 RPL8 tumors 17440064
ENSG00000161016 RPL8 tumors 23227181
ENSG00000161016 RPL8 tumors 29530001
ENSG00000161016 RPL8 GBM 29687002
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000161016 RPL8 STAD 0.031 low
ENSG00000161016 RPL8 UVM 0.048 high
ENSG00000161016 RPL8 UCEC 0.0079 low
ENSG00000161016 RPL8 LGG 0.013 low
ENSG00000161016 RPL8 READ 0.05 high
ENSG00000161016 RPL8 KICH 0.0024 high
ENSG00000161016 RPL8 PCPG 0.0011 high
ENSG00000161016 RPL8 BRCA 0.035 low
ENSG00000161016 RPL8 COAD 0.02 high
ENSG00000161016 RPL8 KIRC 0.0033 high
ENSG00000161016 RPL8 PRAD 0.015 high
ENSG00000161016 RPL8 BLCA 0.017 low
ENSG00000161016 RPL8 LAML 0.022 high
ENSG00000161016 RPL8 SKCM 0.00075 high
ENSG00000161016 RPL8 CESC 0.04 high
ENSG00000161016 RPL8 LIHC 0.0015 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency