Welcome to
RBP World!
| Ensembl ID | ENSG00000160211 | Gene ID | 2539 | Accession | 4057 |
| Gene Symbol | G6PD | Alias | G6PD1 | Full Name | glucose-6-phosphate dehydrogenase |
| Position | X : 154517825 - 154547572 | Length | 29748 bases | Strand | Minus strand |
| Status | Confidence | Main interacting RNAs | N.A. | RBP type | Non-canonical_RBPs |
| Summary | This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | ||||
ENSG00000160211 Expression In 33 Tumors
| Ensembl ID | Gene symbol | Log2 Foldchange | Pvaue | Cancer |
|---|---|---|---|---|
| ENSG00000160211 | G6PD | 0.61 | 4.95e-11 | BRCA |
| ENSG00000160211 | G6PD | 1.09 | 2.41e-18 | KICH |
| ENSG00000160211 | G6PD | 1.78 | 1.35e-22 | LUSC |
| ENSG00000160211 | G6PD | 1.57 | 1.13e-13 | KIRP |
| ENSG00000160211 | G6PD | 2.59 | 5.38e-34 | LIHC |
| ENSG00000160211 | G6PD | 1.33 | 2.20e-14 | UCEC |
| ENSG00000160211 | G6PD | 2.88 | 1.51e-11 | CHOL |
| ENSG00000160211 | G6PD | 1.33 | 7.21e-13 | LUAD |
| Ensembl ID | Gene symbol | Cancer types | Pubmed ID |
|---|---|---|---|
| ENSG00000160211 | G6PD | tumors | 10709108 |
| ENSG00000160211 | G6PD | tumors | 10854566 |
| ENSG00000160211 | G6PD | tumour | 10878554 |
| ENSG00000160211 | G6PD | cancer | 10970068 |
| ENSG00000160211 | G6PD | cancer | 11376568 |
| ENSG00000160211 | G6PD | cancer | 11916749 |
| ENSG00000160211 | G6PD | cancer | 12475725 |
| ENSG00000160211 | G6PD | breast cancer | 12547330 |
| ENSG00000160211 | G6PD | AML | 1373089 |
| ENSG00000160211 | G6PD | tumor lysis syndrome | 16204390 |
| ENSG00000160211 | G6PD | bladder cancer | 16600798 |
| ENSG00000160211 | G6PD | cancer | 17101723 |
| ENSG00000160211 | G6PD | breast cancer | 17314274 |
| ENSG00000160211 | G6PD | tumor | 18302154 |
| ENSG00000160211 | G6PD | breast cancer | 1832909 |
| ENSG00000160211 | G6PD | tumor | 1851399 |
| ENSG00000160211 | G6PD | tumor | 1914015 |
| ENSG00000160211 | G6PD | tumor | 19243250 |
| ENSG00000160211 | G6PD | cancer | 19500819 |
| ENSG00000160211 | G6PD | tumor | 19524183 |
| ENSG00000160211 | G6PD | tumor | 19997593 |
| ENSG00000160211 | G6PD | tumor | 20043092 |
| ENSG00000160211 | G6PD | lung cancer | 2017792 |
| ENSG00000160211 | G6PD | tumor | 20186333 |
| ENSG00000160211 | G6PD | prostate cancer | 20881409 |
| ENSG00000160211 | G6PD | lung cancer | 20924795 |
| ENSG00000160211 | G6PD | Tumour | 21336310 |
| ENSG00000160211 | G6PD | colon cancer | 21679161 |
| ENSG00000160211 | G6PD | acute myeloid leukemia (AML) | 21921332 |
| ENSG00000160211 | G6PD | gastric cancer | 22012600 |
| ENSG00000160211 | G6PD | cancer | 2224469 |
| ENSG00000160211 | G6PD | cancer | 22431005 |
| ENSG00000160211 | G6PD | Cancer | 22535206 |
| ENSG00000160211 | G6PD | Breast cancer | 22735678 |
| ENSG00000160211 | G6PD | breast cancer | 2297768 |
| ENSG00000160211 | G6PD | cancer | 22989772 |
| ENSG00000160211 | G6PD | cancer | 23023104 |
| ENSG00000160211 | G6PD | tumor | 23086271 |
| ENSG00000160211 | G6PD | AML | 23150832 |
| ENSG00000160211 | G6PD | tumors | 23307044 |
| ENSG00000160211 | G6PD | cancer | 23534950 |
| ENSG00000160211 | G6PD | tumor | 23693134 |
| ENSG00000160211 | G6PD | lung cancer | 23742107 |
| ENSG00000160211 | G6PD | tumors | 23811687 |
| ENSG00000160211 | G6PD | cancer | 24066844 |
| ENSG00000160211 | G6PD | tumor | 24152564 |
| ENSG00000160211 | G6PD | tumor | 24203292 |
| ENSG00000160211 | G6PD | tumors | 24270845 |
| ENSG00000160211 | G6PD | cancer | 24342878 |
| ENSG00000160211 | G6PD | tumors | 24359630 |
| ENSG00000160211 | G6PD | cancer | 24738035 |
| ENSG00000160211 | G6PD | cancers | 24832603 |
| ENSG00000160211 | G6PD | prostate cancer | 24861463 |
| ENSG00000160211 | G6PD | cancer | 24929815 |
| ENSG00000160211 | G6PD | tumor | 24994855 |
| ENSG00000160211 | G6PD | cancers | 25015087 |
| ENSG00000160211 | G6PD | tumour | 25205946 |
| ENSG00000160211 | G6PD | breast cancer | 25229745 |
| ENSG00000160211 | G6PD | cancer | 25250177 |
| ENSG00000160211 | G6PD | tumors | 25322816 |
| ENSG00000160211 | G6PD | tumor | 25473368 |
| ENSG00000160211 | G6PD | cancer | 25560241 |
| ENSG00000160211 | G6PD | tumor | 25616277 |
| ENSG00000160211 | G6PD | cancer | 25633909 |
| ENSG00000160211 | G6PD | tumor | 25644430 |
| ENSG00000160211 | G6PD | cancers | 25870517 |
| ENSG00000160211 | G6PD | tumor | 25918195 |
| ENSG00000160211 | G6PD | bladder cancer | 26126921 |
| ENSG00000160211 | G6PD | tumor | 26175932 |
| ENSG00000160211 | G6PD | tumors | 26250461 |
| ENSG00000160211 | G6PD | tumors | 26329784 |
| ENSG00000160211 | G6PD | breast cancer | 26342198 |
| ENSG00000160211 | G6PD | tumor | 26399441 |
| ENSG00000160211 | G6PD | cancer | 26543237 |
| ENSG00000160211 | G6PD | tumor | 26569310 |
| ENSG00000160211 | G6PD | tumor | 26583321 |
| ENSG00000160211 | G6PD | cancer | 26607846 |
| ENSG00000160211 | G6PD | tumor | 26621836 |
| ENSG00000160211 | G6PD | liver tumors | 26667451 |
| ENSG00000160211 | G6PD | cancer | 26715276 |
| ENSG00000160211 | G6PD | cancer | 26802575 |
| ENSG00000160211 | G6PD | cancer | 26956544 |
| ENSG00000160211 | G6PD | bladder cancer | 26975021 |
| ENSG00000160211 | G6PD | Cancer | 26976705 |
| ENSG00000160211 | G6PD | cancer | 2706739 |
| ENSG00000160211 | G6PD | tumor | 27070090 |
| ENSG00000160211 | G6PD | breast cancer | 27078845 |
| ENSG00000160211 | G6PD | tumor | 27212034 |
| ENSG00000160211 | G6PD | cervical cancer | 27217331 |
| ENSG00000160211 | G6PD | cancer | 27232511 |
| ENSG00000160211 | G6PD | cancer | 27277675 |
| ENSG00000160211 | G6PD | cancer | 27356773 |
| ENSG00000160211 | G6PD | breast tumors | 2752532 |
| ENSG00000160211 | G6PD | AML | 27586085 |
| ENSG00000160211 | G6PD | cancer | 27605433 |
| ENSG00000160211 | G6PD | cancers | 27755120 |
| ENSG00000160211 | G6PD | tumor | 27803767 |
| ENSG00000160211 | G6PD | cancer | 27858887 |
| ENSG00000160211 | G6PD | cervical cancer | 27861141 |
| ENSG00000160211 | G6PD | tumor | 27872579 |
| ENSG00000160211 | G6PD | cancer | 27878450 |
| ENSG00000160211 | G6PD | tumor lysis syndrome | 28078984 |
| ENSG00000160211 | G6PD | tumor | 28096627 |
| ENSG00000160211 | G6PD | cancer | 28155142 |
| ENSG00000160211 | G6PD | cancer | 28280275 |
| ENSG00000160211 | G6PD | tumor | 28367246 |
| ENSG00000160211 | G6PD | cancer | 28396842 |
| ENSG00000160211 | G6PD | AML | 28402154 |
| ENSG00000160211 | G6PD | ovarian cancer | 28412735 |
| ENSG00000160211 | G6PD | tumors | 28422979 |
| ENSG00000160211 | G6PD | colon cancer | 28542136 |
| ENSG00000160211 | G6PD | tumor | 28553614 |
| ENSG00000160211 | G6PD | tumor | 28575806 |
| ENSG00000160211 | G6PD | tumor | 28596515 |
| ENSG00000160211 | G6PD | cancer | 28627690 |
| ENSG00000160211 | G6PD | Tumour | 28670638 |
| ENSG00000160211 | G6PD | colorectal cancer | 28692052 |
| ENSG00000160211 | G6PD | tumors | 28744456 |
| ENSG00000160211 | G6PD | acute myeloid leukemia (AML) | 28894556 |
| ENSG00000160211 | G6PD | tumor | 28912546 |
| ENSG00000160211 | G6PD | lung cancer | 28918043 |
| ENSG00000160211 | G6PD | tumors | 28930221 |
| ENSG00000160211 | G6PD | cancer | 28950694 |
| ENSG00000160211 | G6PD | cancer | 29048387 |
| ENSG00000160211 | G6PD | thyroid tumors | 2913822 |
| ENSG00000160211 | G6PD | tumor | 29138396 |
| ENSG00000160211 | G6PD | cancer | 29158891 |
| ENSG00000160211 | G6PD | Cancer | 29169374 |
| ENSG00000160211 | G6PD | cancer | 29212304 |
| ENSG00000160211 | G6PD | breast cancer | 29290982 |
| ENSG00000160211 | G6PD | tumours | 29291545 |
| ENSG00000160211 | G6PD | tumor | 29312589 |
| ENSG00000160211 | G6PD | cancer | 29317613 |
| ENSG00000160211 | G6PD | Cancer | 29445340 |
| ENSG00000160211 | G6PD | tumor | 29471502 |
| ENSG00000160211 | G6PD | cancer | 29518025 |
| ENSG00000160211 | G6PD | tumor | 29582163 |
| ENSG00000160211 | G6PD | cancer | 29699064 |
| ENSG00000160211 | G6PD | cancer | 29720963 |
| ENSG00000160211 | G6PD | cancer | 29748501 |
| ENSG00000160211 | G6PD | lung cancer | 29753088 |
| ENSG00000160211 | G6PD | cancer | 29760380 |
| ENSG00000160211 | G6PD | tumor | 29845423 |
| ENSG00000160211 | G6PD | hepatocellular cancer | 29904144 |
| ENSG00000160211 | G6PD | tumor | 29921695 |
| ENSG00000160211 | G6PD | tumor | 29941676 |
| ENSG00000160211 | G6PD | cancer | 29954422 |
| ENSG00000160211 | G6PD | tumour | 29966585 |
| ENSG00000160211 | G6PD | cancer | 30065243 |
| ENSG00000160211 | G6PD | bladder cancer | 30066842 |
| ENSG00000160211 | G6PD | ovarian cancer | 30132561 |
| ENSG00000160211 | G6PD | cancers | 30181873 |
| ENSG00000160211 | G6PD | Testicular Cancer | 30241168 |
| ENSG00000160211 | G6PD | pituitary tumor | 30272333 |
| ENSG00000160211 | G6PD | cervical cancer | 30344744 |
| ENSG00000160211 | G6PD | cancer | 30391648 |
| ENSG00000160211 | G6PD | tumor | 30400061 |
| ENSG00000160211 | G6PD | tumor | 30409970 |
| ENSG00000160211 | G6PD | tumor | 30430110 |
| ENSG00000160211 | G6PD | tumor | 30534944 |
| ENSG00000160211 | G6PD | tumor | 30603059 |
| ENSG00000160211 | G6PD | tumor | 30606699 |
| ENSG00000160211 | G6PD | tumours | 30655616 |
| ENSG00000160211 | G6PD | cancer | 30661088 |
| ENSG00000160211 | G6PD | breast cancer | 30809937 |
| ENSG00000160211 | G6PD | AML | 30813354 |
| ENSG00000160211 | G6PD | cancer | 30921210 |
| ENSG00000160211 | G6PD | breast cancer | 30987650 |
| ENSG00000160211 | G6PD | tumour | 3101728 |
| ENSG00000160211 | G6PD | cancer | 31027492 |
| ENSG00000160211 | G6PD | cancer | 31058257 |
| ENSG00000160211 | G6PD | cancer | 31109224 |
| ENSG00000160211 | G6PD | cancers | 31157165 |
| ENSG00000160211 | G6PD | AML | 31192118 |
| ENSG00000160211 | G6PD | cancer | 31215094 |
| ENSG00000160211 | G6PD | colorectal cancer | 31217728 |
| ENSG00000160211 | G6PD | breast cancer | 31260379 |
| ENSG00000160211 | G6PD | lung cancer | 31285420 |
| ENSG00000160211 | G6PD | AML | 31319822 |
| ENSG00000160211 | G6PD | tumour | 31374989 |
| ENSG00000160211 | G6PD | breast cancer | 31431543 |
| ENSG00000160211 | G6PD | breast cancer | 31488102 |
| ENSG00000160211 | G6PD | Cancer | 31500396 |
| ENSG00000160211 | G6PD | thyroid cancer | 31563469 |
| ENSG00000160211 | G6PD | cancer | 31581069 |
| ENSG00000160211 | G6PD | gastric cancer | 31591390 |
| ENSG00000160211 | G6PD | acute myeloid leukemia (AML) | 3162289 |
| ENSG00000160211 | G6PD | tumor | 31632088 |
| ENSG00000160211 | G6PD | tumor | 31737625 |
| ENSG00000160211 | G6PD | non-small cell lung cancer | 31814893 |
| ENSG00000160211 | G6PD | breast cancer | 3232211 |
| ENSG00000160211 | G6PD | cancer | 3309118 |
| ENSG00000160211 | G6PD | AML | 3470307 |
| ENSG00000160211 | G6PD | cancer | 3576072 |
| ENSG00000160211 | G6PD | tumors | 3581040 |
| ENSG00000160211 | G6PD | breast tumor | 3621197 |
| ENSG00000160211 | G6PD | parathyroid tumors | 3965123 |
| ENSG00000160211 | G6PD | cancers | 5671384 |
| ENSG00000160211 | G6PD | tumors | 619463 |
| ENSG00000160211 | G6PD | cancer | 6746113 |
| ENSG00000160211 | G6PD | bladder tumor | 6935474 |
| ENSG00000160211 | G6PD | tumours | 706792 |
| ENSG00000160211 | G6PD | tumors | 7211845 |
| ENSG00000160211 | G6PD | malignant tumors | 7347823 |
| ENSG00000160211 | G6PD | tumors | 7529041 |
| ENSG00000160211 | G6PD | cancer | 8833623 |
| ENSG00000160211 | G6PD | breast cancer | 9052415 |
| ENSG00000160211 | G6PD | tumor | 9331084 |
| ENSG00000160211 | G6PD | cancer | 9427729 |
| ENSG00000160211 | G6PD | tumor | 9519770 |
| ENSG00000160211 | G6PD | cancers | 9553792 |
| ENSG00000160211 | G6PD | tumor | 9929162 |
| ENSG00000160211 | G6PD | AML | PMC5584773 |
| Ensembl ID | Gene symbol | Disease/phenotype | Mutation type | Mutated / Total samples | Literature |
|---|
| Ensembl ID | Gene symbol | Cancer | P-value | Which worse | show |
|---|---|---|---|---|---|
| ENSG00000160211 | G6PD | MESO | 0.00046 | high | |
| ENSG00000160211 | G6PD | SARC | 0.026 | high | |
| ENSG00000160211 | G6PD | UVM | 0.029 | high | |
| ENSG00000160211 | G6PD | PAAD | 0.02 | high | |
| ENSG00000160211 | G6PD | ACC | 0.0064 | low | |
| ENSG00000160211 | G6PD | LUSC | 0.033 | high | |
| ENSG00000160211 | G6PD | HNSC | 0.0054 | high | |
| ENSG00000160211 | G6PD | LUAD | 0.025 | high | |
| ENSG00000160211 | G6PD | PCPG | 0.01 | low | |
| ENSG00000160211 | G6PD | BRCA | 0.0048 | high | |
| ENSG00000160211 | G6PD | UCS | 0.017 | high | |
| ENSG00000160211 | G6PD | OV | 0.026 | low | |
| ENSG00000160211 | G6PD | BLCA | 0.00078 | high | |
| ENSG00000160211 | G6PD | GBM | 0.027 | high | |
| ENSG00000160211 | G6PD | SKCM | 0.012 | low | |
| ENSG00000160211 | G6PD | CESC | 0.0025 | low |
| Ensembl ID | Gene symbol | Cancer | CNV type | -log10(q-value) | G-score | average amplitude | frequency |
|---|