Ensembl ID ENSG00000160211 Gene ID 2539 Accession 4057
Gene Symbol G6PD Alias G6PD1 Full Name glucose-6-phosphate dehydrogenase
Position X : 154517825 - 154547572 Length 29748 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

ENSG00000160211 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000160211 0.61 4.95e-11 BRCA
ENSG00000160211 1.09 2.41e-18 KICH
ENSG00000160211 1.78 1.35e-22 LUSC
ENSG00000160211 1.57 1.13e-13 KIRP
ENSG00000160211 2.59 5.38e-34 LIHC
ENSG00000160211 1.33 2.20e-14 UCEC
ENSG00000160211 2.88 1.51e-11 CHOL
ENSG00000160211 1.33 7.21e-13 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000160211 tumors 10709108
ENSG00000160211 tumors 10854566
ENSG00000160211 tumour 10878554
ENSG00000160211 cancer 10970068
ENSG00000160211 cancer 11376568
ENSG00000160211 cancer 11916749
ENSG00000160211 cancer 12475725
ENSG00000160211 breast cancer 12547330
ENSG00000160211 AML 1373089
ENSG00000160211 tumor lysis syndrome 16204390
ENSG00000160211 bladder cancer 16600798
ENSG00000160211 cancer 17101723
ENSG00000160211 breast cancer 17314274
ENSG00000160211 tumor 18302154
ENSG00000160211 breast cancer 1832909
ENSG00000160211 tumor 1851399
ENSG00000160211 tumor 1914015
ENSG00000160211 tumor 19243250
ENSG00000160211 cancer 19500819
ENSG00000160211 tumor 19524183
ENSG00000160211 tumor 19997593
ENSG00000160211 tumor 20043092
ENSG00000160211 lung cancer 2017792
ENSG00000160211 tumor 20186333
ENSG00000160211 prostate cancer 20881409
ENSG00000160211 lung cancer 20924795
ENSG00000160211 Tumour 21336310
ENSG00000160211 colon cancer 21679161
ENSG00000160211 acute myeloid leukemia (AML) 21921332
ENSG00000160211 gastric cancer 22012600
ENSG00000160211 cancer 2224469
ENSG00000160211 cancer 22431005
ENSG00000160211 Cancer 22535206
ENSG00000160211 Breast cancer 22735678
ENSG00000160211 breast cancer 2297768
ENSG00000160211 cancer 22989772
ENSG00000160211 cancer 23023104
ENSG00000160211 tumor 23086271
ENSG00000160211 AML 23150832
ENSG00000160211 tumors 23307044
ENSG00000160211 cancer 23534950
ENSG00000160211 tumor 23693134
ENSG00000160211 lung cancer 23742107
ENSG00000160211 tumors 23811687
ENSG00000160211 cancer 24066844
ENSG00000160211 tumor 24152564
ENSG00000160211 tumor 24203292
ENSG00000160211 tumors 24270845
ENSG00000160211 cancer 24342878
ENSG00000160211 tumors 24359630
ENSG00000160211 cancer 24738035
ENSG00000160211 cancers 24832603
ENSG00000160211 prostate cancer 24861463
ENSG00000160211 cancer 24929815
ENSG00000160211 tumor 24994855
ENSG00000160211 cancers 25015087
ENSG00000160211 tumour 25205946
ENSG00000160211 breast cancer 25229745
ENSG00000160211 cancer 25250177
ENSG00000160211 tumors 25322816
ENSG00000160211 tumor 25473368
ENSG00000160211 cancer 25560241
ENSG00000160211 tumor 25616277
ENSG00000160211 cancer 25633909
ENSG00000160211 tumor 25644430
ENSG00000160211 cancers 25870517
ENSG00000160211 tumor 25918195
ENSG00000160211 bladder cancer 26126921
ENSG00000160211 tumor 26175932
ENSG00000160211 tumors 26250461
ENSG00000160211 tumors 26329784
ENSG00000160211 breast cancer 26342198
ENSG00000160211 tumor 26399441
ENSG00000160211 cancer 26543237
ENSG00000160211 tumor 26569310
ENSG00000160211 tumor 26583321
ENSG00000160211 cancer 26607846
ENSG00000160211 tumor 26621836
ENSG00000160211 liver tumors 26667451
ENSG00000160211 cancer 26715276
ENSG00000160211 cancer 26802575
ENSG00000160211 cancer 26956544
ENSG00000160211 bladder cancer 26975021
ENSG00000160211 Cancer 26976705
ENSG00000160211 cancer 2706739
ENSG00000160211 tumor 27070090
ENSG00000160211 breast cancer 27078845
ENSG00000160211 tumor 27212034
ENSG00000160211 cervical cancer 27217331
ENSG00000160211 cancer 27232511
ENSG00000160211 cancer 27277675
ENSG00000160211 cancer 27356773
ENSG00000160211 breast tumors 2752532
ENSG00000160211 AML 27586085
ENSG00000160211 cancer 27605433
ENSG00000160211 cancers 27755120
ENSG00000160211 tumor 27803767
ENSG00000160211 cancer 27858887
ENSG00000160211 cervical cancer 27861141
ENSG00000160211 tumor 27872579
ENSG00000160211 cancer 27878450
ENSG00000160211 tumor lysis syndrome 28078984
ENSG00000160211 tumor 28096627
ENSG00000160211 cancer 28155142
ENSG00000160211 cancer 28280275
ENSG00000160211 tumor 28367246
ENSG00000160211 cancer 28396842
ENSG00000160211 AML 28402154
ENSG00000160211 ovarian cancer 28412735
ENSG00000160211 tumors 28422979
ENSG00000160211 colon cancer 28542136
ENSG00000160211 tumor 28553614
ENSG00000160211 tumor 28575806
ENSG00000160211 tumor 28596515
ENSG00000160211 cancer 28627690
ENSG00000160211 Tumour 28670638
ENSG00000160211 colorectal cancer 28692052
ENSG00000160211 tumors 28744456
ENSG00000160211 acute myeloid leukemia (AML) 28894556
ENSG00000160211 tumor 28912546
ENSG00000160211 lung cancer 28918043
ENSG00000160211 tumors 28930221
ENSG00000160211 cancer 28950694
ENSG00000160211 cancer 29048387
ENSG00000160211 thyroid tumors 2913822
ENSG00000160211 tumor 29138396
ENSG00000160211 cancer 29158891
ENSG00000160211 Cancer 29169374
ENSG00000160211 cancer 29212304
ENSG00000160211 breast cancer 29290982
ENSG00000160211 tumours 29291545
ENSG00000160211 tumor 29312589
ENSG00000160211 cancer 29317613
ENSG00000160211 Cancer 29445340
ENSG00000160211 tumor 29471502
ENSG00000160211 cancer 29518025
ENSG00000160211 tumor 29582163
ENSG00000160211 cancer 29699064
ENSG00000160211 cancer 29720963
ENSG00000160211 cancer 29748501
ENSG00000160211 lung cancer 29753088
ENSG00000160211 cancer 29760380
ENSG00000160211 tumor 29845423
ENSG00000160211 hepatocellular cancer 29904144
ENSG00000160211 tumor 29921695
ENSG00000160211 tumor 29941676
ENSG00000160211 cancer 29954422
ENSG00000160211 tumour 29966585
ENSG00000160211 cancer 30065243
ENSG00000160211 bladder cancer 30066842
ENSG00000160211 ovarian cancer 30132561
ENSG00000160211 cancers 30181873
ENSG00000160211 Testicular Cancer 30241168
ENSG00000160211 pituitary tumor 30272333
ENSG00000160211 cervical cancer 30344744
ENSG00000160211 cancer 30391648
ENSG00000160211 tumor 30400061
ENSG00000160211 tumor 30409970
ENSG00000160211 tumor 30430110
ENSG00000160211 tumor 30534944
ENSG00000160211 tumor 30603059
ENSG00000160211 tumor 30606699
ENSG00000160211 tumours 30655616
ENSG00000160211 cancer 30661088
ENSG00000160211 breast cancer 30809937
ENSG00000160211 AML 30813354
ENSG00000160211 cancer 30921210
ENSG00000160211 breast cancer 30987650
ENSG00000160211 tumour 3101728
ENSG00000160211 cancer 31027492
ENSG00000160211 cancer 31058257
ENSG00000160211 cancer 31109224
ENSG00000160211 cancers 31157165
ENSG00000160211 AML 31192118
ENSG00000160211 cancer 31215094
ENSG00000160211 colorectal cancer 31217728
ENSG00000160211 breast cancer 31260379
ENSG00000160211 lung cancer 31285420
ENSG00000160211 AML 31319822
ENSG00000160211 tumour 31374989
ENSG00000160211 breast cancer 31431543
ENSG00000160211 breast cancer 31488102
ENSG00000160211 Cancer 31500396
ENSG00000160211 thyroid cancer 31563469
ENSG00000160211 cancer 31581069
ENSG00000160211 gastric cancer 31591390
ENSG00000160211 acute myeloid leukemia (AML) 3162289
ENSG00000160211 tumor 31632088
ENSG00000160211 tumor 31737625
ENSG00000160211 non-small cell lung cancer 31814893
ENSG00000160211 breast cancer 3232211
ENSG00000160211 cancer 3309118
ENSG00000160211 AML 3470307
ENSG00000160211 cancer 3576072
ENSG00000160211 tumors 3581040
ENSG00000160211 breast tumor 3621197
ENSG00000160211 parathyroid tumors 3965123
ENSG00000160211 cancers 5671384
ENSG00000160211 tumors 619463
ENSG00000160211 cancer 6746113
ENSG00000160211 bladder tumor 6935474
ENSG00000160211 tumours 706792
ENSG00000160211 tumors 7211845
ENSG00000160211 malignant tumors 7347823
ENSG00000160211 tumors 7529041
ENSG00000160211 cancer 8833623
ENSG00000160211 breast cancer 9052415
ENSG00000160211 tumor 9331084
ENSG00000160211 cancer 9427729
ENSG00000160211 tumor 9519770
ENSG00000160211 cancers 9553792
ENSG00000160211 tumor 9929162
ENSG00000160211 AML PMC5584773
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000160211 MESO 0.00046 high
ENSG00000160211 SARC 0.026 high
ENSG00000160211 UVM 0.029 high
ENSG00000160211 PAAD 0.02 high
ENSG00000160211 ACC 0.0064 low
ENSG00000160211 LUSC 0.033 high
ENSG00000160211 HNSC 0.0054 high
ENSG00000160211 LUAD 0.025 high
ENSG00000160211 PCPG 0.01 low
ENSG00000160211 BRCA 0.0048 high
ENSG00000160211 UCS 0.017 high
ENSG00000160211 OV 0.026 low
ENSG00000160211 BLCA 0.00078 high
ENSG00000160211 GBM 0.027 high
ENSG00000160211 SKCM 0.012 low
ENSG00000160211 CESC 0.0025 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency