Ensembl ID ENSG00000160193 Gene ID 10785 Accession 12756
Gene Symbol WDR4 Alias hWH;Wuho;MIGSB;TRM82;GAMOS6;TRMT82 Full Name WD repeat domain 4
Position 21 : 42843094 - 42879539 Length 36446 bases Strand Minus strand
Status Confidence Main interacting RNAstRNARBP type Non-canonical_RBPs
Summary This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012]

ENSG00000160193 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000160193 WDR4 1.10 1.62e-12 BLCA
ENSG00000160193 WDR4 0.79 3.45e-30 BRCA
ENSG00000160193 WDR4 1.51 9.68e-42 COAD
ENSG00000160193 WDR4 1.71 3.75e-14 READ
ENSG00000160193 WDR4 1.28 6.75e-39 LUSC
ENSG00000160193 WDR4 0.47 8.69e-11 PRAD
ENSG00000160193 WDR4 0.93 2.30e-17 LIHC
ENSG00000160193 WDR4 0.82 1.40e-12 STAD
ENSG00000160193 WDR4 1.10 5.92e-24 UCEC
ENSG00000160193 WDR4 0.90 2.93e-28 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000160193 WDR4 cancer 21499427
ENSG00000160193 WDR4 lung tumor 28691927
ENSG00000160193 WDR4 pancreatic cancer 31666928
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000160193 WDR4 MESO 4e-04 high
ENSG00000160193 WDR4 STAD 0.0035 low
ENSG00000160193 WDR4 UVM 0.00013 high
ENSG00000160193 WDR4 UCEC 0.0073 high
ENSG00000160193 WDR4 LUSC 0.044 low
ENSG00000160193 WDR4 HNSC 0.014 high
ENSG00000160193 WDR4 READ 0.014 low
ENSG00000160193 WDR4 KIRP 0.041 low
ENSG00000160193 WDR4 PCPG 0.00036 low
ENSG00000160193 WDR4 THYM 0.002 low
ENSG00000160193 WDR4 BRCA 0.041 low
ENSG00000160193 WDR4 OV 0.017 high
ENSG00000160193 WDR4 KIRC 0.0031 high
ENSG00000160193 WDR4 LAML 0.021 high
ENSG00000160193 WDR4 GBM 0.031 high
ENSG00000160193 WDR4 SKCM 0.0066 high
ENSG00000160193 WDR4 CESC 0.016 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000160193 WDR4 LUSC Del 0.991730 0.070016 0.359757 0.570858
ENSG00000160193 WDR4 LAML Amp 3.675883 0.103872 1.137394 0.068063
ENSG00000160193 WDR4 STAD Del 1.430619 0.071195 0.382795 0.448980