Ensembl ID ENSG00000159131 Gene ID 2618 Accession 4163
Gene Symbol GART Alias AIRS;GARS;PAIS;PGFT;PRGS;GARTF Full Name phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
Position 21 : 33503931 - 33543491 Length 39561 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The protein encoded by this gene is a trifunctional polypeptide. It has phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase activity which is required for de novo purine biosynthesis. This enzyme is highly conserved in vertebrates. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

ENSG00000159131 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000159131 GART 0.44 2.64e-16 BRCA
ENSG00000159131 GART 0.92 1.87e-37 COAD
ENSG00000159131 GART 1.10 5.74e-44 LUSC
ENSG00000159131 GART 1.19 2.21e-14 GBM
ENSG00000159131 GART 0.67 7.22e-13 STAD
ENSG00000159131 GART 0.90 6.25e-36 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000159131 GART tumor 12234990
ENSG00000159131 GART colorectal cancer 12651806
ENSG00000159131 GART cancer 17198385
ENSG00000159131 GART cancer 19007868
ENSG00000159131 GART tumor 24444710
ENSG00000159131 GART tumor 24830618
ENSG00000159131 GART Cancer 28617219
ENSG00000159131 GART cancer 29843204
ENSG00000159131 GART tumor 30116770
ENSG00000159131 GART tumor 30473706
ENSG00000159131 GART lung cancer 30642283
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000159131 GART MESO 0.01 high
ENSG00000159131 GART SARC 0.0016 high
ENSG00000159131 GART STAD 0.025 low
ENSG00000159131 GART PAAD 3e-04 high
ENSG00000159131 GART UCEC 0.0066 high
ENSG00000159131 GART ACC 2e-04 high
ENSG00000159131 GART LGG 0.0024 high
ENSG00000159131 GART READ 0.0015 low
ENSG00000159131 GART LUAD 0.02 high
ENSG00000159131 GART PCPG 0.025 low
ENSG00000159131 GART COAD 0.015 low
ENSG00000159131 GART ESCA 0.028 low
ENSG00000159131 GART DLBC 0.0092 low
ENSG00000159131 GART KIRC 0.0054 high
ENSG00000159131 GART PRAD 0.00032 high
ENSG00000159131 GART GBM 0.0044 low
ENSG00000159131 GART SKCM 0.037 high
ENSG00000159131 GART CESC 0.00073 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency