Ensembl ID
ENSG00000159131
Gene ID
2618
Accession
4163
Gene Symbol
GART
Alias
AIRS;GARS;PAIS;PGFT;PRGS;GARTF
Full Name
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
Position
21 : 33503931 - 33543491
Length
39561 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs N.A. RBP type
Non-canonical_RBPs
Summary
The protein encoded by this gene is a trifunctional polypeptide. It has phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase activity which is required for de novo purine biosynthesis. This enzyme is highly conserved in vertebrates. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
ENSG00000159131 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000159131
0.44
2.64e-16
BRCA
ENSG00000159131
0.92
1.87e-37
COAD
ENSG00000159131
1.10
5.74e-44
LUSC
ENSG00000159131
1.19
2.21e-14
GBM
ENSG00000159131
0.67
7.22e-13
STAD
ENSG00000159131
0.90
6.25e-36
LUAD
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000159131
MESO
0.01
high
show
ENSG00000159131
SARC
0.0016
high
show
ENSG00000159131
STAD
0.025
low
show
ENSG00000159131
PAAD
3e-04
high
show
ENSG00000159131
UCEC
0.0066
high
show
ENSG00000159131
ACC
2e-04
high
show
ENSG00000159131
LGG
0.0024
high
show
ENSG00000159131
READ
0.0015
low
show
ENSG00000159131
LUAD
0.02
high
show
ENSG00000159131
PCPG
0.025
low
show
ENSG00000159131
COAD
0.015
low
show
ENSG00000159131
ESCA
0.028
low
show
ENSG00000159131
DLBC
0.0092
low
show
ENSG00000159131
KIRC
0.0054
high
show
ENSG00000159131
PRAD
0.00032
high
show
ENSG00000159131
GBM
0.0044
low
show
ENSG00000159131
SKCM
0.037
high
show
ENSG00000159131
CESC
0.00073
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
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