Ensembl ID ENSG00000158042 Gene ID 63875 Accession 14053
Gene Symbol MRPL17 Alias LIP2;L17mt;bL17m;RPL17L;RPML26;MRP-L17;MRP-L26 Full Name mitochondrial ribosomal protein L17
Position 11 : 6680385 - 6683340 Length 2956 bases Strand Minus strand
Status Confidence Main interacting RNAsrRNARBP type Canonical_RBPs
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]

ENSG00000158042 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000158042 MRPL17 0.53 1.21e-13 KIRC
ENSG00000158042 MRPL17 1.00 3.32e-63 BRCA
ENSG00000158042 MRPL17 1.22 4.56e-41 COAD
ENSG00000158042 MRPL17 0.73 1.38e-17 LUSC
ENSG00000158042 MRPL17 0.81 1.51e-18 PRAD
ENSG00000158042 MRPL17 0.91 1.77e-19 UCEC
ENSG00000158042 MRPL17 0.80 7.52e-21 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000158042 MRPL17 cancer 29236289
ENSG00000158042 MRPL17 lung cancer 31322542
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000158042 MRPL17 MESO 0.0083 high
ENSG00000158042 MRPL17 CHOL 0.014 low
ENSG00000158042 MRPL17 UVM 0.00024 high
ENSG00000158042 MRPL17 THCA 0.005 low
ENSG00000158042 MRPL17 ACC 0.0017 high
ENSG00000158042 MRPL17 HNSC 0.0057 high
ENSG00000158042 MRPL17 KICH 0.0024 high
ENSG00000158042 MRPL17 LUAD 0.0023 high
ENSG00000158042 MRPL17 PCPG 0.029 high
ENSG00000158042 MRPL17 COAD 0.0056 low
ENSG00000158042 MRPL17 OV 0.0021 low
ENSG00000158042 MRPL17 DLBC 0.038 low
ENSG00000158042 MRPL17 PRAD 0.022 high
ENSG00000158042 MRPL17 LAML 0.027 high
ENSG00000158042 MRPL17 GBM 0.0017 high
ENSG00000158042 MRPL17 SKCM 0.0059 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000158042 MRPL17 LUSC Del 7.960000 0.136142 0.366881 0.457086
ENSG00000158042 MRPL17 LUAD Del 1.056765 0.056231 0.293239 0.263566
ENSG00000158042 MRPL17 LGG Del 6.460589 0.084206 0.577452 0.185185
ENSG00000158042 MRPL17 SARC Del 0.809880 0.123852 0.497922 0.392996
ENSG00000158042 MRPL17 GBM Del 0.617041 0.050474 0.484085 0.201040
ENSG00000158042 MRPL17 PAAD Del 0.939270 0.050602 0.339183 0.146739
ENSG00000158042 MRPL17 HNSC Del 0.917189 0.056829 0.356598 0.300766
ENSG00000158042 MRPL17 PCPG Del 1.688309 0.078860 0.627459 0.358025
ENSG00000158042 MRPL17 BLCA Del 1.488105 0.090486 0.426631 0.531863
ENSG00000158042 MRPL17 BRCA Del 7.905356 0.106260 0.422662 0.277778
ENSG00000158042 MRPL17 UCEC Del 2.530336 0.068293 0.520643 0.189239
ENSG00000158042 MRPL17 OV Del 26.431434 0.426702 0.597800 0.571675