Ensembl ID ENSG00000157349 Gene ID 11269 Accession 2742
Gene Symbol DDX19B Alias DBP5;RNAh;DDX19 Full Name DEAD-box helicase 19B
Position 16 : 70289663 - 70335305 Length 45643 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which exhibits RNA-dependent ATPase and ATP-dependent RNA-unwinding activities. This protein is recruited to the cytoplasmic fibrils of the nuclear pore complex, where it participates in the export of mRNA from the nucleus. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

ENSG00000157349 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000157349 DDX19B -0.3 9.14e-15 BRCA
ENSG00000157349 DDX19B 0.57 1.15e-13 KIRP
ENSG00000157349 DDX19B -0.8 1.56e-20 LIHC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000157349 DDX19B kidney tumors 10918353
ENSG00000157349 DDX19B prostate cancer 25385343
ENSG00000157349 DDX19B tumors 28174618
ENSG00000157349 DDX19B cancer 30873535
ENSG00000157349 DDX19B thyroid cancer 31349573
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000157349 DDX19B MESO 0.00011 low
ENSG00000157349 DDX19B STAD 0.015 low
ENSG00000157349 DDX19B CHOL 0.017 low
ENSG00000157349 DDX19B UVM 0.043 high
ENSG00000157349 DDX19B UCEC 0.047 low
ENSG00000157349 DDX19B ACC 0.008 high
ENSG00000157349 DDX19B LGG 0.014 high
ENSG00000157349 DDX19B HNSC 0.038 high
ENSG00000157349 DDX19B READ 0.025 low
ENSG00000157349 DDX19B KIRP 0.00011 low
ENSG00000157349 DDX19B LUAD 0.002 low
ENSG00000157349 DDX19B PCPG 0.021 high
ENSG00000157349 DDX19B THYM 0.00088 low
ENSG00000157349 DDX19B BRCA 0.021 low
ENSG00000157349 DDX19B COAD 0.04 high
ENSG00000157349 DDX19B UCS 0.014 low
ENSG00000157349 DDX19B ESCA 0.036 high
ENSG00000157349 DDX19B KIRC 0.003 low
ENSG00000157349 DDX19B GBM 0.0077 low
ENSG00000157349 DDX19B SKCM 0.0076 low
ENSG00000157349 DDX19B CESC 0.035 low
ENSG00000157349 DDX19B LIHC 0.005 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000157349 DDX19B LAML Del 1.466386 0.041379 0.608754 0.036649
ENSG00000157349 DDX19B ACC Amp 0.865367 0.267997 1.091365 0.577778
ENSG00000157349 DDX19B TGCT Amp 0.748581 0.119204 0.578998 0.140000
ENSG00000157349 DDX19B BLCA Amp 0.926894 0.172851 0.487445 0.262255
ENSG00000157349 DDX19B PRAD Del 7.592364 0.133791 0.519141 0.317073
ENSG00000157349 DDX19B UCEC Del 3.526690 0.077131 0.624740 0.276438
ENSG00000157349 DDX19B OV Del 9.439781 0.294690 0.658787 0.768566