Ensembl ID ENSG00000157349 Gene ID 11269 Accession 2742
Gene Symbol DDX19B Alias DBP5;RNAh;DDX19 Full Name DEAD-box helicase 19B
Position 16 : 70289663 - 70335305 Length 45643 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which exhibits RNA-dependent ATPase and ATP-dependent RNA-unwinding activities. This protein is recruited to the cytoplasmic fibrils of the nuclear pore complex, where it participates in the export of mRNA from the nucleus. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

ENSG00000157349 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000157349 -0.3 9.14e-15 BRCA
ENSG00000157349 0.57 1.15e-13 KIRP
ENSG00000157349 -0.8 1.56e-20 LIHC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000157349 kidney tumors 10918353
ENSG00000157349 prostate cancer 25385343
ENSG00000157349 tumors 28174618
ENSG00000157349 cancer 30873535
ENSG00000157349 thyroid cancer 31349573
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000157349 MESO 0.00011 low
ENSG00000157349 STAD 0.015 low
ENSG00000157349 CHOL 0.017 low
ENSG00000157349 UVM 0.043 high
ENSG00000157349 UCEC 0.047 low
ENSG00000157349 ACC 0.008 high
ENSG00000157349 LGG 0.014 high
ENSG00000157349 HNSC 0.038 high
ENSG00000157349 READ 0.025 low
ENSG00000157349 KIRP 0.00011 low
ENSG00000157349 LUAD 0.002 low
ENSG00000157349 PCPG 0.021 high
ENSG00000157349 THYM 0.00088 low
ENSG00000157349 BRCA 0.021 low
ENSG00000157349 COAD 0.04 high
ENSG00000157349 UCS 0.014 low
ENSG00000157349 ESCA 0.036 high
ENSG00000157349 KIRC 0.003 low
ENSG00000157349 GBM 0.0077 low
ENSG00000157349 SKCM 0.0076 low
ENSG00000157349 CESC 0.035 low
ENSG00000157349 LIHC 0.005 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000157349 LAML Del 1.466386 0.041379 0.608754 0.036649
ENSG00000157349 ACC Amp 0.865367 0.267997 1.091365 0.577778
ENSG00000157349 TGCT Amp 0.748581 0.119204 0.578998 0.140000
ENSG00000157349 BLCA Amp 0.926894 0.172851 0.487445 0.262255
ENSG00000157349 PRAD Del 7.592364 0.133791 0.519141 0.317073
ENSG00000157349 UCEC Del 3.526690 0.077131 0.624740 0.276438
ENSG00000157349 OV Del 9.439781 0.294690 0.658787 0.768566