Ensembl ID ENSG00000157106 Gene ID 23049 Accession 30045
Gene Symbol SMG1 Alias ATX;LIP;61E3.4 Full Name SMG1 nonsense mediated mRNA decay associated PI3K related kinase
Position 16 : 18804860 - 18926408 Length 121549 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Non-canonical_RBPs
Summary This gene encodes a protein involved in nonsense-mediated mRNA decay (NMD) as part of the mRNA surveillance complex. The protein has kinase activity and is thought to function in NMD by phosphorylating the regulator of nonsense transcripts 1 protein. Alternatively spliced transcript variants have been described, but their full-length nature has yet to be determined. [provided by RefSeq, Mar 2013]

ENSG00000157106 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000157106 SMG1 cancer 11544179
ENSG00000157106 SMG1 DLBCL 16239949
ENSG00000157106 SMG1 tumor 19406746
ENSG00000157106 SMG1 pancreatic cancer 20871480
ENSG00000157106 SMG1 tumor 21301799
ENSG00000157106 SMG1 non-small cell lung cancer 21418860
ENSG00000157106 SMG1 cancer 21490678
ENSG00000157106 SMG1 tumor 22247495
ENSG00000157106 SMG1 tumour 22479207
ENSG00000157106 SMG1 tumor 23021994
ENSG00000157106 SMG1 tumor 24107632
ENSG00000157106 SMG1 tumor 24700316
ENSG00000157106 SMG1 acute myeloid leukemia (AML) 25257528
ENSG00000157106 SMG1 lung cancer 25520033
ENSG00000157106 SMG1 pancreatic cancer 25760059
ENSG00000157106 SMG1 tumors 26806738
ENSG00000157106 SMG1 HNSCC 26870181
ENSG00000157106 SMG1 gastric cancer 26897165
ENSG00000157106 SMG1 liver cancer 26998062
ENSG00000157106 SMG1 tumors 27308324
ENSG00000157106 SMG1 non-small-cell lung cancer 27743168
ENSG00000157106 SMG1 DLBCL 27806315
ENSG00000157106 SMG1 tumor 28107519
ENSG00000157106 SMG1 tumor 29239144
ENSG00000157106 SMG1 cancer 30405107
ENSG00000157106 SMG1 AML 30634713
ENSG00000157106 SMG1 tumours 31164688
ENSG00000157106 SMG1 pancreatic cancer 31469826
ENSG00000157106 SMG1 cancer 31565865
ENSG00000157106 SMG1 tumor 31659158
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000157106 SMG1 STAD 0.012 low
ENSG00000157106 SMG1 CHOL 0.045 low
ENSG00000157106 SMG1 PAAD 0.011 high
ENSG00000157106 SMG1 UCEC 0.034 high
ENSG00000157106 SMG1 THCA 0.033 high
ENSG00000157106 SMG1 LGG 0.015 high
ENSG00000157106 SMG1 LUSC 0.044 high
ENSG00000157106 SMG1 HNSC 0.013 low
ENSG00000157106 SMG1 KICH 0.02 high
ENSG00000157106 SMG1 THYM 0.016 low
ENSG00000157106 SMG1 UCS 0.026 high
ENSG00000157106 SMG1 ESCA 0.036 low
ENSG00000157106 SMG1 KIRC 0.0049 low
ENSG00000157106 SMG1 PRAD 0.045 low
ENSG00000157106 SMG1 LAML 0.011 low
ENSG00000157106 SMG1 GBM 0.016 low
ENSG00000157106 SMG1 SKCM 0.00072 low
ENSG00000157106 SMG1 CESC 0.041 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency