Ensembl ID ENSG00000156508 Gene ID 1915 Accession 3189
Gene Symbol EEF1A1 Alias CCS3;EF1A;PTI1;CCS-3;EE1A1;EEF-1;EEF1A;EF-Tu;EF1A1;LENG7;eEF1A-1;GRAF-1EF;EF1alpha1 Full Name eukaryotic translation elongation factor 1 alpha 1
Position 6 : 73489308 - 73525587 Length 36280 bases Strand Minus strand
Status Confidence Main interacting RNAstRNARBP type Canonical_RBPs
Summary This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes, some of which, if not all, represent different pseudogenes. [provided by RefSeq, Jul 2008]

ENSG00000156508 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000156508 EEF1A1 -0.7 4.14e-20 HNSC
ENSG00000156508 EEF1A1 -1.0 3.08e-12 BLCA
ENSG00000156508 EEF1A1 -0.6 7.75e-29 BRCA
ENSG00000156508 EEF1A1 2.20 7.09e-15 GBM
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000156508 EEF1A1 cancer 14588074
ENSG00000156508 EEF1A1 breast cancer 15843208
ENSG00000156508 EEF1A1 cancer 15986332
ENSG00000156508 EEF1A1 cancer 16054525
ENSG00000156508 EEF1A1 tumour 16156888
ENSG00000156508 EEF1A1 GBM 16314830
ENSG00000156508 EEF1A1 cancers 17825975
ENSG00000156508 EEF1A1 ovarian cancer 17908984
ENSG00000156508 EEF1A1 cancer 17912428
ENSG00000156508 EEF1A1 ovarian cancer 17936057
ENSG00000156508 EEF1A1 ovarian cancer 18218611
ENSG00000156508 EEF1A1 cancer 18221514
ENSG00000156508 EEF1A1 prostate cancers 18649364
ENSG00000156508 EEF1A1 tumor 19114010
ENSG00000156508 EEF1A1 colon cancer 19487283
ENSG00000156508 EEF1A1 breast cancer 19646290
ENSG00000156508 EEF1A1 pancreatic cancer 19732436
ENSG00000156508 EEF1A1 cancer 20599650
ENSG00000156508 EEF1A1 breast cancer 20832312
ENSG00000156508 EEF1A1 tumour 20838377
ENSG00000156508 EEF1A1 gastric cancer 22072909
ENSG00000156508 EEF1A1 prostate cancer 22095224
ENSG00000156508 EEF1A1 prostate cancer 22355332
ENSG00000156508 EEF1A1 tumor 22569823
ENSG00000156508 EEF1A1 cancer 22708801
ENSG00000156508 EEF1A1 tumours 22930480
ENSG00000156508 EEF1A1 lung cancer 23533664
ENSG00000156508 EEF1A1 tumors 23799104
ENSG00000156508 EEF1A1 cervical cancer 24506961
ENSG00000156508 EEF1A1 cancer 24710046
ENSG00000156508 EEF1A1 cancer 25233275
ENSG00000156508 EEF1A1 cervical cancer 25893434
ENSG00000156508 EEF1A1 lung cancer 25905039
ENSG00000156508 EEF1A1 cancer 26179970
ENSG00000156508 EEF1A1 tumor 26222051
ENSG00000156508 EEF1A1 lung cancer 26518718
ENSG00000156508 EEF1A1 tumors 27109021
ENSG00000156508 EEF1A1 cancer 27150264
ENSG00000156508 EEF1A1 Tumor 27312528
ENSG00000156508 EEF1A1 cancer 28108655
ENSG00000156508 EEF1A1 cancer 28345336
ENSG00000156508 EEF1A1 gastric cancer 28393218
ENSG00000156508 EEF1A1 tumours 28678185
ENSG00000156508 EEF1A1 breast cancer 28827731
ENSG00000156508 EEF1A1 tumor 28900796
ENSG00000156508 EEF1A1 tumor 29058591
ENSG00000156508 EEF1A1 tumor 29079187
ENSG00000156508 EEF1A1 Tumor 29248802
ENSG00000156508 EEF1A1 tumor 29342219
ENSG00000156508 EEF1A1 cancer 29498519
ENSG00000156508 EEF1A1 prostate tumor 29507675
ENSG00000156508 EEF1A1 lung cancer 29844511
ENSG00000156508 EEF1A1 tumors 30224719
ENSG00000156508 EEF1A1 breast cancer 30250408
ENSG00000156508 EEF1A1 cancer 30878835
ENSG00000156508 EEF1A1 breast cancer 31105998
ENSG00000156508 EEF1A1 Cancer 31324856
ENSG00000156508 EEF1A1 cancer 31450069
ENSG00000156508 EEF1A1 colon cancer 31703307
ENSG00000156508 EEF1A1 cancer 31777262
ENSG00000156508 EEF1A1 tumors 31862491
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000156508 EEF1A1 MESO 0.022 low
ENSG00000156508 EEF1A1 SARC 0.0078 high
ENSG00000156508 EEF1A1 UVM 0.011 low
ENSG00000156508 EEF1A1 UCEC 0.042 low
ENSG00000156508 EEF1A1 ACC 0.018 high
ENSG00000156508 EEF1A1 HNSC 0.041 high
ENSG00000156508 EEF1A1 READ 0.013 low
ENSG00000156508 EEF1A1 KIRP 0.031 high
ENSG00000156508 EEF1A1 KICH 0.013 high
ENSG00000156508 EEF1A1 THYM 0.00016 low
ENSG00000156508 EEF1A1 BRCA 0.021 low
ENSG00000156508 EEF1A1 DLBC 0.018 high
ENSG00000156508 EEF1A1 LAML 0.034 low
ENSG00000156508 EEF1A1 GBM 0.042 low
ENSG00000156508 EEF1A1 CESC 0.0047 high
ENSG00000156508 EEF1A1 LIHC 0.0028 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000156508 EEF1A1 CHOL Del 0.840293 0.216530 0.629156 0.555556
ENSG00000156508 EEF1A1 LUAD Del 0.636511 0.050146 0.368452 0.434109
ENSG00000156508 EEF1A1 SARC Del 1.397606 0.141966 0.460130 0.280156
ENSG00000156508 EEF1A1 BRCA Del 1.590459 0.071375 0.462642 0.275000
ENSG00000156508 EEF1A1 PRAD Del 11.400136 0.157776 0.495024 0.203252