Ensembl ID ENSG00000155846 Gene ID 133522 Accession 30022
Gene Symbol PPARGC1B Alias PERC;ERRL1;PGC1B;PGC-1(beta) Full Name PPARG coactivator 1 beta
Position 5 : 149730298 - 149855022 Length 124725 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

ENSG00000155846 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000155846 PPARGC1B 0.73 2.09e-13 KIRC
ENSG00000155846 PPARGC1B -0.9 1.00e-21 BRCA
ENSG00000155846 PPARGC1B -1.3 6.79e-31 COAD
ENSG00000155846 PPARGC1B -1.2 4.45e-24 PRAD
ENSG00000155846 PPARGC1B -1.4 3.46e-26 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000155846 PPARGC1B tumor 1563006
ENSG00000155846 PPARGC1B familial breast cancer 16704985
ENSG00000155846 PPARGC1B colorectal tumor 17341490
ENSG00000155846 PPARGC1B tumors 1893374
ENSG00000155846 PPARGC1B Kidney Cancer 20169137
ENSG00000155846 PPARGC1B prostate cancer 20477822
ENSG00000155846 PPARGC1B breast cancer 20889127
ENSG00000155846 PPARGC1B breast cancer 20961995
ENSG00000155846 PPARGC1B breast cancer 21269472
ENSG00000155846 PPARGC1B breast cancers 22014575
ENSG00000155846 PPARGC1B tumors 22341440
ENSG00000155846 PPARGC1B tumor 23070475
ENSG00000155846 PPARGC1B breast cancer 23866026
ENSG00000155846 PPARGC1B breast cancer 23877360
ENSG00000155846 PPARGC1B tumors 24350057
ENSG00000155846 PPARGC1B breast cancer 24904222
ENSG00000155846 PPARGC1B tumour 25268374
ENSG00000155846 PPARGC1B tumor 25288742
ENSG00000155846 PPARGC1B tumor 25736869
ENSG00000155846 PPARGC1B tumors 25791281
ENSG00000155846 PPARGC1B tumors 25938254
ENSG00000155846 PPARGC1B cancer 25975952
ENSG00000155846 PPARGC1B Colon Tumor 26351140
ENSG00000155846 PPARGC1B breast cancer 26602383
ENSG00000155846 PPARGC1B breast cancer 26749280
ENSG00000155846 PPARGC1B tumor 27086599
ENSG00000155846 PPARGC1B Colon Tumors 27273865
ENSG00000155846 PPARGC1B breast cancer 27557380
ENSG00000155846 PPARGC1B tumors 2790783
ENSG00000155846 PPARGC1B colon cancer 28007957
ENSG00000155846 PPARGC1B cancer 28507102
ENSG00000155846 PPARGC1B Cancer 28572074
ENSG00000155846 PPARGC1B breast cancer 28821609
ENSG00000155846 PPARGC1B tumor 28857232
ENSG00000155846 PPARGC1B breast cancer 29018241
ENSG00000155846 PPARGC1B tumor 29064738
ENSG00000155846 PPARGC1B tumor 29121859
ENSG00000155846 PPARGC1B cancer 29361779
ENSG00000155846 PPARGC1B Prostate Cancer 29483070
ENSG00000155846 PPARGC1B cancer 29888964
ENSG00000155846 PPARGC1B tumor 30051603
ENSG00000155846 PPARGC1B cancer 30122956
ENSG00000155846 PPARGC1B tumor 30254608
ENSG00000155846 PPARGC1B thyroid cancer 30768848
ENSG00000155846 PPARGC1B cancer 30809968
ENSG00000155846 PPARGC1B breast tumor 30911677
ENSG00000155846 PPARGC1B tumor 31007610
ENSG00000155846 PPARGC1B breast cancer 31058090
ENSG00000155846 PPARGC1B cancer 31060333
ENSG00000155846 PPARGC1B Tumour 31615341
ENSG00000155846 PPARGC1B liver cancer 31623280
ENSG00000155846 PPARGC1B tumor 31695789
ENSG00000155846 PPARGC1B tumours 31833575
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000155846 PPARGC1B MESO 0.0021 low
ENSG00000155846 PPARGC1B CHOL 0.024 low
ENSG00000155846 PPARGC1B PAAD 0.044 high
ENSG00000155846 PPARGC1B UCEC 0.00091 high
ENSG00000155846 PPARGC1B HNSC 0.0018 low
ENSG00000155846 PPARGC1B READ 0.0029 low
ENSG00000155846 PPARGC1B KICH 0.00038 high
ENSG00000155846 PPARGC1B PCPG 0.011 low
ENSG00000155846 PPARGC1B THYM 0.018 high
ENSG00000155846 PPARGC1B COAD 0.029 low
ENSG00000155846 PPARGC1B UCS 0.0087 high
ENSG00000155846 PPARGC1B ESCA 0.0026 high
ENSG00000155846 PPARGC1B OV 0.029 high
ENSG00000155846 PPARGC1B PRAD 0.024 low
ENSG00000155846 PPARGC1B BLCA 0.006 low
ENSG00000155846 PPARGC1B CESC 0.02 low
ENSG00000155846 PPARGC1B LIHC 0.0026 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000155846 PPARGC1B LAML Del 6.887040 0.098062 0.803117 0.089005
ENSG00000155846 PPARGC1B LGG Del 3.144246 0.061836 0.423850 0.101365
ENSG00000155846 PPARGC1B ACC Amp 0.847626 0.265130 1.214118 0.677778
ENSG00000155846 PPARGC1B SKCM Del 6.120277 0.133930 0.498026 0.337875
ENSG00000155846 PPARGC1B LIHC Amp 0.609252 0.108755 0.538531 0.335135
ENSG00000155846 PPARGC1B KIRC Amp 52.984248 0.299605 0.545028 0.613636