Ensembl ID ENSG00000155846 Gene ID 133522 Accession 30022
Gene Symbol PPARGC1B Alias PERC;ERRL1;PGC1B;PGC-1(beta) Full Name PPARG coactivator 1 beta
Position 5 : 149730298 - 149855022 Length 124725 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

ENSG00000155846 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000155846 0.73 2.09e-13 KIRC
ENSG00000155846 -0.9 1.00e-21 BRCA
ENSG00000155846 -1.3 6.79e-31 COAD
ENSG00000155846 -1.2 4.45e-24 PRAD
ENSG00000155846 -1.4 3.46e-26 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000155846 tumor 1563006
ENSG00000155846 familial breast cancer 16704985
ENSG00000155846 colorectal tumor 17341490
ENSG00000155846 tumors 1893374
ENSG00000155846 Kidney Cancer 20169137
ENSG00000155846 prostate cancer 20477822
ENSG00000155846 breast cancer 20889127
ENSG00000155846 breast cancer 20961995
ENSG00000155846 breast cancer 21269472
ENSG00000155846 breast cancers 22014575
ENSG00000155846 tumors 22341440
ENSG00000155846 tumor 23070475
ENSG00000155846 breast cancer 23866026
ENSG00000155846 breast cancer 23877360
ENSG00000155846 tumors 24350057
ENSG00000155846 breast cancer 24904222
ENSG00000155846 tumour 25268374
ENSG00000155846 tumor 25288742
ENSG00000155846 tumor 25736869
ENSG00000155846 tumors 25791281
ENSG00000155846 tumors 25938254
ENSG00000155846 cancer 25975952
ENSG00000155846 Colon Tumor 26351140
ENSG00000155846 breast cancer 26602383
ENSG00000155846 breast cancer 26749280
ENSG00000155846 tumor 27086599
ENSG00000155846 Colon Tumors 27273865
ENSG00000155846 breast cancer 27557380
ENSG00000155846 tumors 2790783
ENSG00000155846 colon cancer 28007957
ENSG00000155846 cancer 28507102
ENSG00000155846 Cancer 28572074
ENSG00000155846 breast cancer 28821609
ENSG00000155846 tumor 28857232
ENSG00000155846 breast cancer 29018241
ENSG00000155846 tumor 29064738
ENSG00000155846 tumor 29121859
ENSG00000155846 cancer 29361779
ENSG00000155846 Prostate Cancer 29483070
ENSG00000155846 cancer 29888964
ENSG00000155846 tumor 30051603
ENSG00000155846 cancer 30122956
ENSG00000155846 tumor 30254608
ENSG00000155846 thyroid cancer 30768848
ENSG00000155846 cancer 30809968
ENSG00000155846 breast tumor 30911677
ENSG00000155846 tumor 31007610
ENSG00000155846 breast cancer 31058090
ENSG00000155846 cancer 31060333
ENSG00000155846 Tumour 31615341
ENSG00000155846 liver cancer 31623280
ENSG00000155846 tumor 31695789
ENSG00000155846 tumours 31833575
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000155846 MESO 0.0021 low
ENSG00000155846 CHOL 0.024 low
ENSG00000155846 PAAD 0.044 high
ENSG00000155846 UCEC 0.00091 high
ENSG00000155846 HNSC 0.0018 low
ENSG00000155846 READ 0.0029 low
ENSG00000155846 KICH 0.00038 high
ENSG00000155846 PCPG 0.011 low
ENSG00000155846 THYM 0.018 high
ENSG00000155846 COAD 0.029 low
ENSG00000155846 UCS 0.0087 high
ENSG00000155846 ESCA 0.0026 high
ENSG00000155846 OV 0.029 high
ENSG00000155846 PRAD 0.024 low
ENSG00000155846 BLCA 0.006 low
ENSG00000155846 CESC 0.02 low
ENSG00000155846 LIHC 0.0026 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000155846 LAML Del 6.887040 0.098062 0.803117 0.089005
ENSG00000155846 LGG Del 3.144246 0.061836 0.423850 0.101365
ENSG00000155846 ACC Amp 0.847626 0.265130 1.214118 0.677778
ENSG00000155846 SKCM Del 6.120277 0.133930 0.498026 0.337875
ENSG00000155846 LIHC Amp 0.609252 0.108755 0.538531 0.335135
ENSG00000155846 KIRC Amp 52.984248 0.299605 0.545028 0.613636