Ensembl ID ENSG00000155508 Gene ID 9337 Accession 9207
Gene Symbol CNOT8 Alias CAF1;POP2;CALIF;Caf1b;hCAF1 Full Name CCR4-NOT transcription complex subunit 8
Position 5 : 154858249 - 154876792 Length 18544 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary Enables poly(A)-specific ribonuclease activity. Involved in exonucleolytic catabolism of deadenylated mRNA and positive regulation of cell population proliferation. Located in nucleus. Part of CCR4-NOT complex. [provided by Alliance of Genome Resources, Apr 2022]

ENSG00000155508 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000155508 CNOT8 -0.7 1.15e-27 LUSC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000155508 CNOT8 pancreatic cancer 24354864
ENSG00000155508 CNOT8 cancer 25191340
ENSG00000155508 CNOT8 cancer 30353606
ENSG00000155508 CNOT8 tumor 31140748
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000155508 CNOT8 MESO 0.0091 low
ENSG00000155508 CNOT8 SARC 0.049 high
ENSG00000155508 CNOT8 PAAD 0.014 high
ENSG00000155508 CNOT8 UCEC 0.036 high
ENSG00000155508 CNOT8 THCA 0.025 high
ENSG00000155508 CNOT8 KIRP 0.0019 low
ENSG00000155508 CNOT8 KICH 0.012 high
ENSG00000155508 CNOT8 LUAD 0.019 low
ENSG00000155508 CNOT8 THYM 0.0094 low
ENSG00000155508 CNOT8 COAD 0.021 high
ENSG00000155508 CNOT8 ESCA 0.0086 high
ENSG00000155508 CNOT8 OV 0.0079 low
ENSG00000155508 CNOT8 BLCA 5e-04 low
ENSG00000155508 CNOT8 LAML 0.0024 low
ENSG00000155508 CNOT8 GBM 0.027 low
ENSG00000155508 CNOT8 LIHC 0.0015 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000155508 CNOT8 LAML Del 6.075308 0.088993 0.803426 0.083770
ENSG00000155508 CNOT8 LGG Del 5.466761 0.078086 0.443635 0.115010
ENSG00000155508 CNOT8 SKCM Del 5.127561 0.123310 0.497388 0.343324
ENSG00000155508 CNOT8 KIRC Amp 50.764756 0.290896 0.544704 0.607955