Ensembl ID
ENSG00000153187
Gene ID
3192
Accession
5048
Gene Symbol
HNRNPU
Alias
SAFA;DEE54;HNRPU;SAF-A;U21.1;pp120;EIEE54;GRIP120;hnRNPU;HNRNPU-AS1
Full Name
heterogeneous nuclear ribonucleoprotein U
Position
1 : 244840638 - 244864560
Length
23923 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs mRNA RBP type
Canonical_RBPs
Summary
This gene encodes a member of a family of proteins that bind nucleic acids and function in the formation of ribonucleoprotein complexes in the nucleus with heterogeneous nuclear RNA (hnRNA). The encoded protein has affinity for both RNA and DNA, and binds scaffold-attached region (SAR) DNA. Mutations in this gene have been associated with epileptic encephalopathy, early infantile, 54. A pseudogene of this gene has been identified on chromosome 14. [provided by RefSeq, Jun 2017]
ENSG00000153187 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000153187
HNRNPU
-0.2
2.29e-13
KIRC
ENSG00000153187
HNRNPU
0.55
1.70e-69
BRCA
ENSG00000153187
HNRNPU
0.43
2.59e-15
COAD
ENSG00000153187
HNRNPU
0.35
2.34e-11
LUSC
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000153187
HNRNPU
tumor
10356358
ENSG00000153187
HNRNPU
tumor
11694516
ENSG00000153187
HNRNPU
cancer
12188916
ENSG00000153187
HNRNPU
tumor
12665652
ENSG00000153187
HNRNPU
tumour
16924231
ENSG00000153187
HNRNPU
tumor
18772145
ENSG00000153187
HNRNPU
tumor
20093774
ENSG00000153187
HNRNPU
GBM
20668194
ENSG00000153187
HNRNPU
tumor
21194727
ENSG00000153187
HNRNPU
oral cancer
22259181
ENSG00000153187
HNRNPU
breast cancer
24495796
ENSG00000153187
HNRNPU
tumours
25406515
ENSG00000153187
HNRNPU
tumor
26067913
ENSG00000153187
HNRNPU
tumor
26506240
ENSG00000153187
HNRNPU
Cancer
28622508
ENSG00000153187
HNRNPU
tumour
28947659
ENSG00000153187
HNRNPU
tumor
29228625
ENSG00000153187
HNRNPU
tumor
29434445
ENSG00000153187
HNRNPU
cancer
29511351
ENSG00000153187
HNRNPU
pancreatic cancer
29657295
ENSG00000153187
HNRNPU
prostate cancer
30177244
ENSG00000153187
HNRNPU
gastric cancer
30336538
ENSG00000153187
HNRNPU
colon cancer
31311954
ENSG00000153187
HNRNPU
liver cancer
31331910
ENSG00000153187
HNRNPU
tumor
31495606
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000153187
HNRNPU
MESO
0.0019
high
show
ENSG00000153187
HNRNPU
SARC
0.048
high
show
ENSG00000153187
HNRNPU
PAAD
0.02
high
show
ENSG00000153187
HNRNPU
LGG
0.00024
high
show
ENSG00000153187
HNRNPU
HNSC
0.042
high
show
ENSG00000153187
HNRNPU
READ
0.013
low
show
ENSG00000153187
HNRNPU
LUAD
0.00091
high
show
ENSG00000153187
HNRNPU
THYM
0.011
low
show
ENSG00000153187
HNRNPU
OV
0.047
low
show
ENSG00000153187
HNRNPU
PRAD
0.0033
high
show
ENSG00000153187
HNRNPU
TGCT
0.033
low
show
ENSG00000153187
HNRNPU
BLCA
0.039
high
show
ENSG00000153187
HNRNPU
GBM
0.025
low
show
ENSG00000153187
HNRNPU
SKCM
0.035
low
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000153187
HNRNPU
LUAD
Amp
1.869676
0.146485
0.503220
0.684109
ENSG00000153187
HNRNPU
CESC
Amp
1.232730
0.149636
0.589511
0.511864
ENSG00000153187
HNRNPU
SARC
Del
4.779471
0.212739
0.479230
0.291829
ENSG00000153187
HNRNPU
GBM
Amp
2.423455
0.097657
0.630704
0.164645
ENSG00000153187
HNRNPU
ESCA
Amp
0.888844
0.272231
0.511820
0.500000
ENSG00000153187
HNRNPU
SKCM
Amp
5.935928
0.265257
0.710570
0.553134
ENSG00000153187
HNRNPU
LIHC
Amp
7.255211
0.246091
0.839526
0.724324
ENSG00000153187
HNRNPU
PCPG
Del
0.885132
0.062820
0.537894
0.129630
ENSG00000153187
HNRNPU
DLBC
Del
1.770602
0.184953
0.511109
0.187500
ENSG00000153187
HNRNPU
BRCA
Amp
17.751877
0.331847
0.799913
0.737037
ENSG00000153187
HNRNPU
UCEC
Amp
3.125789
0.153209
0.865810
0.413729
ENSG00000153187
HNRNPU
KIRC
Del
0.682869
0.024196
0.458910
0.079545
ENSG00000153187
HNRNPU
OV
Amp
8.380275
0.517917
0.750751
0.533679
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