Ensembl ID ENSG00000152795 Gene ID 9987 Accession 5037
Gene Symbol HNRNPDL Alias HNRNP;JKTBP;HNRPDL;JKTBP2;LGMD1G;LGMDD3;laAUF1 Full Name heterogeneous nuclear ribonucleoprotein D like
Position 4 : 82422565 - 82430462 Length 7898 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind to RNAs. Three alternatively spliced transcript variants have been described for this gene. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein isoforms encoded by this gene are similar to its family member HNRPD. [provided by RefSeq, May 2011]

ENSG00000152795 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000152795 HNRNPDL -0.2 2.21e-17 BRCA
ENSG00000152795 HNRNPDL 0.46 1.45e-14 COAD
ENSG00000152795 HNRNPDL -0.4 1.02e-11 UCEC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000152795 HNRNPDL malignant brain tumor 22192797
ENSG00000152795 HNRNPDL cervical cancer 24013563
ENSG00000152795 HNRNPDL colon cancer 30052712
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000152795 HNRNPDL SARC 0.01 high
ENSG00000152795 HNRNPDL UCEC 0.0027 low
ENSG00000152795 HNRNPDL ACC 0.00017 high
ENSG00000152795 HNRNPDL LGG 0.0037 low
ENSG00000152795 HNRNPDL LUSC 0.035 high
ENSG00000152795 HNRNPDL READ 0.035 low
ENSG00000152795 HNRNPDL KIRP 0.043 high
ENSG00000152795 HNRNPDL THYM 0.015 low
ENSG00000152795 HNRNPDL KIRC 0.018 high
ENSG00000152795 HNRNPDL PRAD 0.019 high
ENSG00000152795 HNRNPDL TGCT 0.019 low
ENSG00000152795 HNRNPDL BLCA 0.018 low
ENSG00000152795 HNRNPDL SKCM 0.0013 low
ENSG00000152795 HNRNPDL LIHC 0.02 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000152795 HNRNPDL LIHC Del 4.542639 0.116458 0.559494 0.454054
ENSG00000152795 HNRNPDL BLCA Del 1.023496 0.083056 0.349396 0.360294
ENSG00000152795 HNRNPDL STAD Del 1.511018 0.072177 0.337185 0.417234
ENSG00000152795 HNRNPDL OV Del 1.483377 0.192596 0.610547 0.616580