Ensembl ID
ENSG00000152778
Gene ID
24138
Accession
13328
Gene Symbol
IFIT5
Alias
P58;RI58;ISG58
Full Name
interferon induced protein with tetratricopeptide repeats 5
Position
10 : 89414568 - 89421605
Length
7038 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs tRNA RBP type
Non-canonical_RBPs
Summary
Enables nucleic acid binding activity. Involved in defense response to virus; negative regulation of viral genome replication; and positive regulation of I-kappaB kinase/NF-kappaB signaling. Located in actin cytoskeleton; apical part of cell; and ruffle membrane. Colocalizes with IkappaB kinase complex. [provided by Alliance of Genome Resources, Apr 2022]
ENSG00000152778 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000152778
IFIT5
-0.8
9.75e-13
KICH
ENSG00000152778
IFIT5
-1.0
4.17e-25
LUSC
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000152778
IFIT5
tumor
25844669
ENSG00000152778
IFIT5
cancer
29844869
ENSG00000152778
IFIT5
Prostate Cancer
30504123
ENSG00000152778
IFIT5
prostate cancer
30877097
ENSG00000152778
IFIT5
renal cancer
30906803
ENSG00000152778
IFIT5
bladder cancer
31164632
ENSG00000152778
IFIT5
cancer
31494269
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000152778
IFIT5
MESO
0.0065
low
show
ENSG00000152778
IFIT5
SARC
0.015
low
show
ENSG00000152778
IFIT5
CHOL
0.0035
low
show
ENSG00000152778
IFIT5
UCEC
0.025
high
show
ENSG00000152778
IFIT5
THCA
0.036
low
show
ENSG00000152778
IFIT5
HNSC
0.035
high
show
ENSG00000152778
IFIT5
KIRP
0.045
low
show
ENSG00000152778
IFIT5
PCPG
0.0068
low
show
ENSG00000152778
IFIT5
THYM
0.0056
low
show
ENSG00000152778
IFIT5
LAML
0.00027
high
show
ENSG00000152778
IFIT5
GBM
0.0025
low
show
ENSG00000152778
IFIT5
LIHC
0.042
low
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000152778
IFIT5
LUSC
Del
4.531804
0.108697
0.379358
0.518962
ENSG00000152778
IFIT5
LGG
Del
0.882710
0.040942
0.547906
0.224172
ENSG00000152778
IFIT5
CESC
Del
2.410838
0.097622
0.459605
0.298305
ENSG00000152778
IFIT5
READ
Del
1.053150
0.082019
0.433750
0.309091
ENSG00000152778
IFIT5
COAD
Del
5.640037
0.085220
0.388510
0.226164
ENSG00000152778
IFIT5
SARC
Del
0.701212
0.120060
0.563043
0.525292
ENSG00000152778
IFIT5
GBM
Del
4.346515
0.087438
0.704747
0.887348
ENSG00000152778
IFIT5
ESCA
Del
1.586164
0.121798
0.382624
0.353261
ENSG00000152778
IFIT5
THCA
Del
1.956122
0.015187
0.507180
0.022044
ENSG00000152778
IFIT5
HNSC
Del
2.856945
0.076117
0.353616
0.256705
ENSG00000152778
IFIT5
LIHC
Del
1.003036
0.070811
0.500274
0.256757
ENSG00000152778
IFIT5
DLBC
Del
2.449370
0.227808
0.785172
0.145833
ENSG00000152778
IFIT5
BLCA
Del
4.316672
0.126575
0.417175
0.406863
ENSG00000152778
IFIT5
BRCA
Del
7.985261
0.106661
0.394124
0.295370
ENSG00000152778
IFIT5
STAD
Del
4.618793
0.105074
0.390151
0.247166
ENSG00000152778
IFIT5
PRAD
Del
21.964064
0.213229
0.522690
0.245935
ENSG00000152778
IFIT5
UCEC
Del
7.484161
0.104850
0.555998
0.139147
ENSG00000152778
IFIT5
MESO
Del
0.673292
0.121954
0.467682
0.310345
ENSG00000152778
IFIT5
OV
Del
10.560685
0.305161
0.562356
0.392055
Copyright © 2023, Bioinformatics Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China. All Rights Reserved.