Ensembl ID
ENSG00000152700
Gene ID
51128
Accession
10535
Gene Symbol
SAR1B
Alias
ANDD;CMRD;GTBPB;SARA2
Full Name
secretion associated Ras related GTPase 1B
Position
5 : 134601149 - 134649271
Length
48123 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs N.A. RBP type
Canonical_RBPs
Summary
The protein encoded by this gene is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010]
ENSG00000152700 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000152700
SAR1B
-0.9
6.89e-36
HNSC
ENSG00000152700
SAR1B
-0.6
4.22e-16
COAD
ENSG00000152700
SAR1B
-0.7
4.03e-13
STAD
ENSG00000152700
SAR1B
-2.2
3.19e-15
CHOL
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000152700
SAR1B
AML
27870639
ENSG00000152700
SAR1B
HNSCC
29454310
ENSG00000152700
SAR1B
cancer
29729190
ENSG00000152700
SAR1B
tumor
31097715
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000152700
SAR1B
SARC
0.0072
low
show
ENSG00000152700
SAR1B
STAD
0.047
high
show
ENSG00000152700
SAR1B
UCEC
0.00085
low
show
ENSG00000152700
SAR1B
THCA
0.0021
high
show
ENSG00000152700
SAR1B
LUSC
0.05
high
show
ENSG00000152700
SAR1B
HNSC
0.047
high
show
ENSG00000152700
SAR1B
KICH
0.00026
high
show
ENSG00000152700
SAR1B
THYM
0.0059
high
show
ENSG00000152700
SAR1B
BRCA
0.021
high
show
ENSG00000152700
SAR1B
COAD
0.01
low
show
ENSG00000152700
SAR1B
UCS
0.03
high
show
ENSG00000152700
SAR1B
PRAD
0.033
high
show
ENSG00000152700
SAR1B
TGCT
0.00098
low
show
ENSG00000152700
SAR1B
BLCA
0.021
low
show
ENSG00000152700
SAR1B
LAML
0.0039
low
show
ENSG00000152700
SAR1B
LIHC
0.0014
low
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000152700
SAR1B
LAML
Del
6.887040
0.097495
0.799843
0.089005
ENSG00000152700
SAR1B
LUAD
Del
3.126409
0.078052
0.346910
0.408915
ENSG00000152700
SAR1B
LGG
Del
0.780773
0.039887
0.383767
0.087719
ENSG00000152700
SAR1B
ACC
Amp
0.881753
0.270261
1.218942
0.677778
ENSG00000152700
SAR1B
COAD
Del
1.062207
0.046571
0.391939
0.219512
ENSG00000152700
SAR1B
SKCM
Del
2.789662
0.097350
0.491787
0.321526
ENSG00000152700
SAR1B
PCPG
Del
0.615867
0.055469
0.663237
0.074074
ENSG00000152700
SAR1B
STAD
Del
2.572211
0.085188
0.389624
0.335601
ENSG00000152700
SAR1B
KIRC
Amp
44.958428
0.268503
0.536596
0.592803
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