Ensembl ID
ENSG00000152332
Gene ID
127933
Accession
19683
Gene Symbol
UHMK1
Alias
KIS;KIST;P-CIP2
Full Name
U2AF homology motif kinase 1
Position
1 : 162497251 - 162529631
Length
32381 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs mRNA RBP type
Canonical_RBPs
Summary
The gene encodes a serine/threonine protein kinase that promotes cell cycle progression through G1 by phosphorylation of the cyclin-dependent kinase inhibitor 1B (p27Kip1), which causes nuclear export and degradation. The encoded protein is also thought to function in the adult nervous system and the gene has been associated with schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
ENSG00000152332 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000152332
UHMK1
-0.5
8.78e-15
KIRC
ENSG00000152332
UHMK1
0.64
1.21e-23
BRCA
ENSG00000152332
UHMK1
0.71
1.04e-11
STAD
ENSG00000152332
UHMK1
0.61
1.22e-15
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000152332
UHMK1
tumors
12782393
ENSG00000152332
UHMK1
esophageal cancer
1287463
ENSG00000152332
UHMK1
esophageal cancer
1287472
ENSG00000152332
UHMK1
AML
18384876
ENSG00000152332
UHMK1
tumor
19436953
ENSG00000152332
UHMK1
breast cancer
21045138
ENSG00000152332
UHMK1
Breast cancer
24579540
ENSG00000152332
UHMK1
bladder cancer
25656485
ENSG00000152332
UHMK1
breast cancer
27510838
ENSG00000152332
UHMK1
ovarian cancer
28427776
ENSG00000152332
UHMK1
tumor
2852183
ENSG00000152332
UHMK1
ovarian cancer
28800944
ENSG00000152332
UHMK1
colon cancer
28970512
ENSG00000152332
UHMK1
pancreatic cancer
29074453
ENSG00000152332
UHMK1
lung cancer
29856124
ENSG00000152332
UHMK1
Cancer
30196752
ENSG00000152332
UHMK1
liver cancer
30936457
ENSG00000152332
UHMK1
tumor
31569420
ENSG00000152332
UHMK1
DLBCL
31955451
ENSG00000152332
UHMK1
gastric cancer
31975428
ENSG00000152332
UHMK1
tumor
8185331
ENSG00000152332
UHMK1
tumor
8910496
ENSG00000152332
UHMK1
tumour
9722295
ENSG00000152332
UHMK1
tumor
9808580
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000152332
UHMK1
SARC
0.049
low
show
ENSG00000152332
UHMK1
STAD
0.033
low
show
ENSG00000152332
UHMK1
CHOL
0.044
low
show
ENSG00000152332
UHMK1
UVM
0.00066
high
show
ENSG00000152332
UHMK1
PAAD
0.0092
high
show
ENSG00000152332
UHMK1
ACC
0.00087
high
show
ENSG00000152332
UHMK1
LGG
0.00091
high
show
ENSG00000152332
UHMK1
KIRP
0.001
low
show
ENSG00000152332
UHMK1
KICH
0.016
high
show
ENSG00000152332
UHMK1
LUAD
0.016
high
show
ENSG00000152332
UHMK1
PCPG
7e-04
high
show
ENSG00000152332
UHMK1
UCS
0.0078
high
show
ENSG00000152332
UHMK1
KIRC
0.0036
low
show
ENSG00000152332
UHMK1
PRAD
0.019
high
show
ENSG00000152332
UHMK1
BLCA
0.0088
low
show
ENSG00000152332
UHMK1
SKCM
0.0013
low
show
ENSG00000152332
UHMK1
LIHC
0.028
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000152332
UHMK1
LUSC
Amp
3.240422
0.267582
0.557973
0.520958
ENSG00000152332
UHMK1
LUAD
Amp
8.885323
0.261117
0.551303
0.722868
ENSG00000152332
UHMK1
CESC
Amp
1.690002
0.167465
0.616465
0.535593
ENSG00000152332
UHMK1
READ
Amp
0.657946
0.120696
0.609563
0.278788
ENSG00000152332
UHMK1
SARC
Amp
2.854884
0.367730
0.711599
0.354086
ENSG00000152332
UHMK1
ESCA
Amp
0.617135
0.253469
0.513846
0.478261
ENSG00000152332
UHMK1
SKCM
Amp
2.935908
0.187930
0.717083
0.536785
ENSG00000152332
UHMK1
LIHC
Amp
13.709288
0.340026
0.904442
0.745946
ENSG00000152332
UHMK1
DLBC
Amp
1.946352
0.301216
0.636224
0.291667
ENSG00000152332
UHMK1
BLCA
Amp
37.084870
0.792963
0.901344
0.500000
ENSG00000152332
UHMK1
BRCA
Amp
16.878998
0.324851
0.803870
0.738889
ENSG00000152332
UHMK1
UCEC
Amp
3.595027
0.160818
0.841981
0.441558
ENSG00000152332
UHMK1
OV
Amp
2.603794
0.392212
0.669902
0.569948
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