Ensembl ID ENSG00000150753 Gene ID 22948 Accession 1618
Gene Symbol CCT5 Alias CCTE;HEL-S-69;PNAS-102;CCT-epsilon;TCP-1-epsilon Full Name chaperonin containing TCP1 subunit 5
Position 5 : 10249929 - 10266389 Length 16461 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13. [provided by RefSeq, Apr 2015]

ENSG00000150753 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000150753 0.71 1.22e-15 HNSC
ENSG00000150753 0.89 1.03e-40 BRCA
ENSG00000150753 0.77 9.53e-24 COAD
ENSG00000150753 1.79 6.02e-76 LUSC
ENSG00000150753 0.67 8.17e-15 LIHC
ENSG00000150753 0.78 4.97e-12 STAD
ENSG00000150753 1.08 1.77e-22 UCEC
ENSG00000150753 1.25 8.42e-34 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000150753 breast cancers 16821082
ENSG00000150753 colorectal cancer 16981251
ENSG00000150753 cancer 23282132
ENSG00000150753 tumor 28969060
ENSG00000150753 tumours 29954368
ENSG00000150753 tumor 31934176
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000150753 SARC 0.00032 high
ENSG00000150753 UVM 0.00042 high
ENSG00000150753 PAAD 0.01 high
ENSG00000150753 ACC 0.00017 high
ENSG00000150753 LGG 0.0026 high
ENSG00000150753 LUSC 0.032 low
ENSG00000150753 HNSC 0.002 high
ENSG00000150753 READ 0.023 low
ENSG00000150753 LUAD 0.0027 high
ENSG00000150753 THYM 0.01 low
ENSG00000150753 BRCA 0.0058 high
ENSG00000150753 OV 0.0022 low
ENSG00000150753 DLBC 0.011 low
ENSG00000150753 KIRC 0.00021 high
ENSG00000150753 PRAD 0.012 high
ENSG00000150753 BLCA 0.019 high
ENSG00000150753 LAML 0.039 high
ENSG00000150753 SKCM 0.03 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000150753 LUSC Amp 11.544047 0.423263 0.859282 0.766467
ENSG00000150753 LUAD Amp 12.046860 0.302391 0.750592 0.620155
ENSG00000150753 LGG Del 1.013479 0.042631 0.494572 0.081871
ENSG00000150753 CESC Amp 1.952919 0.177243 0.950739 0.457627
ENSG00000150753 ACC Amp 0.627773 0.237544 1.354006 0.588889
ENSG00000150753 SARC Amp 1.492405 0.305072 0.792492 0.463035
ENSG00000150753 SKCM Amp 1.805365 0.156098 0.698409 0.245232
ENSG00000150753 SKCM Del 1.438641 0.078470 0.466953 0.217984
ENSG00000150753 HNSC Amp 0.646699 0.113772 0.654811 0.452107
ENSG00000150753 BLCA Amp 3.806438 0.260857 0.816176 0.504902
ENSG00000150753 UCEC Amp 1.664195 0.125991 0.844943 0.144712
ENSG00000150753 OV Amp 3.428972 0.414276 0.884622 0.506045