Ensembl ID ENSG00000149532 Gene ID 79869 Accession 30098
Gene Symbol CPSF7 Alias CFIm59 Full Name cleavage and polyadenylation specific factor 7
Position 11 : 61402641 - 61430031 Length 27391 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary Cleavage factor Im (CFIm) is one of six factors necessary for correct cleavage and polyadenylation of pre-mRNAs. CFIm is composed of three different subunits of 25, 59, and 68 kDa, and it functions as a heterotetramer, with a dimer of the 25 kDa subunit binding to two of the 59 or 68 kDa subunits. The protein encoded by this gene represents the 59 kDa subunit, which can interact with the splicing factor U2 snRNP Auxiliary Factor (U2AF) 65 to link the splicing and polyadenylation complexes. [provided by RefSeq, Oct 2016]

ENSG00000149532 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000149532 CPSF7 0.34 2.75e-13 KIRC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000149532 CPSF7 cancer 23939832
ENSG00000149532 CPSF7 breast cancer 29435015
ENSG00000149532 CPSF7 GBM 30705404
ENSG00000149532 CPSF7 liver cancer 31837982
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000149532 CPSF7 MESO 0.049 high
ENSG00000149532 CPSF7 SARC 0.012 high
ENSG00000149532 CPSF7 UCEC 0.0037 high
ENSG00000149532 CPSF7 THCA 0.045 high
ENSG00000149532 CPSF7 HNSC 0.0087 low
ENSG00000149532 CPSF7 READ 0.03 low
ENSG00000149532 CPSF7 KICH 0.021 high
ENSG00000149532 CPSF7 PCPG 0.0049 low
ENSG00000149532 CPSF7 BRCA 0.0034 low
ENSG00000149532 CPSF7 COAD 0.0028 high
ENSG00000149532 CPSF7 UCS 0.034 low
ENSG00000149532 CPSF7 ESCA 0.015 low
ENSG00000149532 CPSF7 PRAD 0.02 high
ENSG00000149532 CPSF7 BLCA 0.005 high
ENSG00000149532 CPSF7 LAML 0.029 high
ENSG00000149532 CPSF7 SKCM 0.048 low
ENSG00000149532 CPSF7 LIHC 0.0028 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000149532 CPSF7 HNSC Amp 1.023087 0.124681 0.402521 0.229885
ENSG00000149532 CPSF7 BRCA Amp 1.378203 0.159147 0.521584 0.192593