Ensembl ID ENSG00000149480 Gene ID 9219 Accession 7411
Gene Symbol MTA2 Alias PID;MTA1L1 Full Name metastasis associated 1 family member 2
Position 11 : 62593214 - 62601865 Length 8652 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacetylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis. [provided by RefSeq, May 2011]

ENSG00000149480 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000149480 0.30 3.83e-12 KIRC
ENSG00000149480 0.41 4.40e-18 BRCA
ENSG00000149480 0.83 2.34e-36 LUSC
ENSG00000149480 0.75 2.32e-22 UCEC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000149480 endometrial cancer 12313083
ENSG00000149480 breast tumors 12684393
ENSG00000149480 tumor 12920132
ENSG00000149480 tumor 14565029
ENSG00000149480 tumour 1580568
ENSG00000149480 tumor 16104317
ENSG00000149480 cancer 16156285
ENSG00000149480 tumor 16309230
ENSG00000149480 cancer 16472146
ENSG00000149480 tumor 16533771
ENSG00000149480 breast tumors 16645043
ENSG00000149480 ovarian epithelial cancer 16961294
ENSG00000149480 breast cancer 18174918
ENSG00000149480 tumors 19047122
ENSG00000149480 ovarian cancer 19125176
ENSG00000149480 tumor 19702911
ENSG00000149480 non-small cell lung cancer 20704817
ENSG00000149480 tumors 20711231
ENSG00000149480 tumor 20720167
ENSG00000149480 cancer 20798238
ENSG00000149480 tumors 21072183
ENSG00000149480 tumors 21447808
ENSG00000149480 tumor 22214225
ENSG00000149480 bladder cancer 22238607
ENSG00000149480 Cancer 22548703
ENSG00000149480 non-small cell lung cancer 22585429
ENSG00000149480 Tumor 22833212
ENSG00000149480 tumour 22969963
ENSG00000149480 gastric cancer 23158992
ENSG00000149480 tumor 23320035
ENSG00000149480 tumor 23400716
ENSG00000149480 cancer 23671646
ENSG00000149480 tumor 23825676
ENSG00000149480 gastric cancer 24010737
ENSG00000149480 tumor 24039159
ENSG00000149480 breast cancer 24077732
ENSG00000149480 Cancer 24098138
ENSG00000149480 hematological cancer 24390342
ENSG00000149480 colorectal cancer 24468085
ENSG00000149480 tumor 24801752
ENSG00000149480 colon cancer 24969834
ENSG00000149480 tumor 25048531
ENSG00000149480 breast cancer 25081667
ENSG00000149480 cancer 25362484
ENSG00000149480 tumor 25391133
ENSG00000149480 cancer 25394532
ENSG00000149480 cancer 25522158
ENSG00000149480 gastric cancer 25929737
ENSG00000149480 non-small-cell lung cancer 25969565
ENSG00000149480 metastatic tumors 26148557
ENSG00000149480 Cancer 26192618
ENSG00000149480 colorectal cancer 26261611
ENSG00000149480 cancer 26369414
ENSG00000149480 cancers 26483332
ENSG00000149480 cancer 26869315
ENSG00000149480 tumor 27051300
ENSG00000149480 gastric cancer 27065326
ENSG00000149480 gastric cancer 27509928
ENSG00000149480 breast cancer 27597141
ENSG00000149480 cancer 27651854
ENSG00000149480 tumor 27682888
ENSG00000149480 cancer 27795744
ENSG00000149480 cervical cancer 27807324
ENSG00000149480 cancers 27893679
ENSG00000149480 tumour 27929134
ENSG00000149480 tumor 27932593
ENSG00000149480 tumor 28279208
ENSG00000149480 tumor 28416018
ENSG00000149480 tumor 28418887
ENSG00000149480 gastric cancer 28502558
ENSG00000149480 tumor 28634344
ENSG00000149480 tumor 28652762
ENSG00000149480 tumor 28669558
ENSG00000149480 breast cancer 28789814
ENSG00000149480 cancer 28790306
ENSG00000149480 tumor 29221183
ENSG00000149480 tumor 29348864
ENSG00000149480 tumor 29393472
ENSG00000149480 tumor 29527288
ENSG00000149480 tumors 29535735
ENSG00000149480 tumor 29565967
ENSG00000149480 cancer 29589566
ENSG00000149480 tumour 29708271
ENSG00000149480 gastric cancer 29743816
ENSG00000149480 tumor 29881389
ENSG00000149480 tumors 29924794
ENSG00000149480 cancer 29988723
ENSG00000149480 Tumor 30150766
ENSG00000149480 cancer 30352985
ENSG00000149480 tumors 30386679
ENSG00000149480 tumor 30400835
ENSG00000149480 cancers 30419907
ENSG00000149480 brain tumors 30443258
ENSG00000149480 breast cancer 30563489
ENSG00000149480 breast cancer 30563971
ENSG00000149480 breast cancer 30642362
ENSG00000149480 cancer 30662522
ENSG00000149480 pancreatic cancer 30814496
ENSG00000149480 prostate cancer 30837551
ENSG00000149480 cancer 31031796
ENSG00000149480 cancer 31250750
ENSG00000149480 tumors 31275905
ENSG00000149480 cancer 31355198
ENSG00000149480 oral cancer 31359510
ENSG00000149480 lung cancer 31388311
ENSG00000149480 cancers 31410216
ENSG00000149480 cancer 31553746
ENSG00000149480 tumor 31607857
ENSG00000149480 gastric tumor 31645899
ENSG00000149480 Renal Cancer 31771219
ENSG00000149480 tumor 31777601
ENSG00000149480 cancer 31942846
ENSG00000149480 benign ovarian tumors 7876758
ENSG00000149480 cervical cancer 8732866
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000149480 MESO 0.0016 high
ENSG00000149480 SARC 0.013 high
ENSG00000149480 STAD 0.0038 low
ENSG00000149480 CHOL 0.016 high
ENSG00000149480 UVM 0.046 high
ENSG00000149480 PAAD 0.0089 high
ENSG00000149480 UCEC 0.016 low
ENSG00000149480 ACC 0.00015 high
ENSG00000149480 LUSC 0.04 low
ENSG00000149480 HNSC 0.02 low
ENSG00000149480 KIRP 0.00037 high
ENSG00000149480 LUAD 0.014 high
ENSG00000149480 PCPG 0.047 low
ENSG00000149480 THYM 0.00032 low
ENSG00000149480 BRCA 0.0063 low
ENSG00000149480 UCS 0.049 low
ENSG00000149480 ESCA 0.0053 low
ENSG00000149480 OV 0.016 low
ENSG00000149480 KIRC 0.00032 high
ENSG00000149480 PRAD 0.024 high
ENSG00000149480 BLCA 0.033 low
ENSG00000149480 SKCM 0.019 low
ENSG00000149480 CESC 0.013 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000149480 HNSC Amp 1.490751 0.136222 0.408681 0.237548
ENSG00000149480 BRCA Del 1.631491 0.071776 0.422856 0.213889
ENSG00000149480 UCEC Amp 0.616126 0.100477 0.514521 0.111317