Ensembl ID ENSG00000149257 Gene ID 871 Accession 1546
Gene Symbol SERPINH1 Alias CBP1;CBP2;OI10;gp46;AsTP3;HSP47;PIG14;PPROM;RA-A47;SERPINH2 Full Name serpin family H member 1
Position 11 : 75562056 - 75572783 Length 10728 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis. Expression of this gene may be a marker for cancer, and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, May 2011]

ENSG00000149257 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000149257 1.55 4.66e-60 KIRC
ENSG00000149257 2.15 1.93e-49 HNSC
ENSG00000149257 0.91 2.06e-25 BRCA
ENSG00000149257 1.13 1.26e-22 COAD
ENSG00000149257 1.05 5.15e-18 LUSC
ENSG00000149257 3.74 1.61e-19 GBM
ENSG00000149257 1.23 3.03e-25 KIRP
ENSG00000149257 1.08 3.90e-15 LIHC
ENSG00000149257 1.35 5.99e-23 STAD
ENSG00000149257 1.09 2.63e-28 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000149257 tumor 10227388
ENSG00000149257 tumor 11400171
ENSG00000149257 tumors 12109856
ENSG00000149257 tumor 12174873
ENSG00000149257 tumors 12710130
ENSG00000149257 head and neck cancers 12881196
ENSG00000149257 cancers 15574354
ENSG00000149257 tumor 16036307
ENSG00000149257 gastric cancer 16475681
ENSG00000149257 tumours 17174144
ENSG00000149257 tumours 18499731
ENSG00000149257 cancer 19603022
ENSG00000149257 gastric cancer 20043075
ENSG00000149257 cancer 20112500
ENSG00000149257 stomach cancer 21060876
ENSG00000149257 cancers 21198874
ENSG00000149257 breast cancer 21401208
ENSG00000149257 tumor 21472683
ENSG00000149257 tumors 2167903
ENSG00000149257 malignant tumors 22101181
ENSG00000149257 tumors 22268080
ENSG00000149257 breast cancer 22795889
ENSG00000149257 gastric cancers 22929309
ENSG00000149257 tumors 23227181
ENSG00000149257 Tumor 24141696
ENSG00000149257 tumor 24595468
ENSG00000149257 benign tumors 24623841
ENSG00000149257 tumor 25034945
ENSG00000149257 tumors 25162504
ENSG00000149257 breast cancer 25572802
ENSG00000149257 tumor 25758142
ENSG00000149257 cancers 26681200
ENSG00000149257 DLBCL 26700650
ENSG00000149257 lung cancer 27488440
ENSG00000149257 Tumor 27696866
ENSG00000149257 tumor 27925182
ENSG00000149257 tumor 2836228
ENSG00000149257 tumours 28849239
ENSG00000149257 tumour 29239102
ENSG00000149257 cancer 30128672
ENSG00000149257 tumour 30139933
ENSG00000149257 tumor 3014533
ENSG00000149257 tumor 30153702
ENSG00000149257 tumor 30194076
ENSG00000149257 tumors 30637779
ENSG00000149257 tumor 30713500
ENSG00000149257 colon cancer 30774653
ENSG00000149257 lung cancer 30841875
ENSG00000149257 cancer 30986427
ENSG00000149257 gastric cancer 31233344
ENSG00000149257 gastric cancer 31249732
ENSG00000149257 cancers 31258024
ENSG00000149257 cancer 31570520
ENSG00000149257 tumors 7803705
ENSG00000149257 tumors 8387039
ENSG00000149257 tumor 8900930
ENSG00000149257 tumours 8900931
ENSG00000149257 tumour 8900932
ENSG00000149257 tumor 9067768
ENSG00000149257 tumor 9239521
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000149257 SARC 0.014 high
ENSG00000149257 STAD 0.024 high
ENSG00000149257 CHOL 0.01 high
ENSG00000149257 PAAD 0.0013 high
ENSG00000149257 UCEC 0.0041 high
ENSG00000149257 THCA 0.0011 high
ENSG00000149257 HNSC 0.00011 high
ENSG00000149257 LUAD 0.0056 high
ENSG00000149257 PCPG 0.033 low
ENSG00000149257 COAD 0.012 high
ENSG00000149257 OV 0.024 low
ENSG00000149257 BLCA 0.02 high
ENSG00000149257 GBM 0.022 high
ENSG00000149257 SKCM 0.035 high
ENSG00000149257 CESC 0.00063 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000149257 LUAD Amp 1.182763 0.130349 0.426253 0.313953
ENSG00000149257 ESCA Amp 4.099041 0.438132 0.798222 0.293478
ENSG00000149257 SKCM Amp 5.000833 0.242464 0.821037 0.158038
ENSG00000149257 HNSC Amp 7.435147 0.241339 0.619377 0.226054
ENSG00000149257 BLCA Amp 0.957952 0.173854 0.538521 0.213235
ENSG00000149257 BRCA Amp 31.295092 0.430248 0.906924 0.231481
ENSG00000149257 STAD Amp 0.805170 0.134059 0.494358 0.224490
ENSG00000149257 UCEC Amp 1.011884 0.111159 0.627143 0.098330
ENSG00000149257 OV Amp 12.232512 0.583731 0.792450 0.414508