Ensembl ID
ENSG00000148840
Gene ID
23082
Accession
30025
Gene Symbol
PPRC1
Alias
PRC
Full Name
PPARG related coactivator 1
Position
10 : 102132994 - 102150333
Length
17340 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs mRNA RBP type
Canonical_RBPs
Summary
The protein encoded by this gene is similar to PPAR-gamma coactivator 1 (PPARGC1/PGC-1), a protein that can activate mitochondrial biogenesis in part through a direct interaction with nuclear respiratory factor 1 (NRF1). This protein has been shown to interact with NRF1. It is thought to be a functional relative of PPAR-gamma coactivator 1 that activates mitochondrial biogenesis through NRF1 in response to proliferative signals. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
ENSG00000148840 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000148840
PPRC1
1.00
1.97e-37
COAD
ENSG00000148840
PPRC1
1.14
4.73e-12
READ
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000148840
PPRC1
kidney cancer
10874308
ENSG00000148840
PPRC1
rectal cancer
12046076
ENSG00000148840
PPRC1
tumors
14550271
ENSG00000148840
PPRC1
gastric cancer
16465421
ENSG00000148840
PPRC1
cancer
16632488
ENSG00000148840
PPRC1
tumors
1673293
ENSG00000148840
PPRC1
cancer
17603928
ENSG00000148840
PPRC1
cancer
17726103
ENSG00000148840
PPRC1
tumors
18636147
ENSG00000148840
PPRC1
Tumours
19956726
ENSG00000148840
PPRC1
tumor
21249316
ENSG00000148840
PPRC1
prostate cancer
21840484
ENSG00000148840
PPRC1
tumors
21881606
ENSG00000148840
PPRC1
cancer
21937425
ENSG00000148840
PPRC1
tumor
21990320
ENSG00000148840
PPRC1
cancer
22126538
ENSG00000148840
PPRC1
liver tumor
22145042
ENSG00000148840
PPRC1
cancer
22305566
ENSG00000148840
PPRC1
cancer
23341493
ENSG00000148840
PPRC1
tumor
23364789
ENSG00000148840
PPRC1
cancer
23455154
ENSG00000148840
PPRC1
tumor
23516535
ENSG00000148840
PPRC1
cancer
23733246
ENSG00000148840
PPRC1
renal cancer
24204800
ENSG00000148840
PPRC1
cancer
24277643
ENSG00000148840
PPRC1
cancers
24407023
ENSG00000148840
PPRC1
lung cancer
24611018
ENSG00000148840
PPRC1
gastric cancers
24744581
ENSG00000148840
PPRC1
breast cancer
24853546
ENSG00000148840
PPRC1
cancers
25115192
ENSG00000148840
PPRC1
tumor
25232004
ENSG00000148840
PPRC1
cancers
25424424
ENSG00000148840
PPRC1
Cancer
25835323
ENSG00000148840
PPRC1
cancer
25960768
ENSG00000148840
PPRC1
cancer
25960784
ENSG00000148840
PPRC1
tumor
26448339
ENSG00000148840
PPRC1
gastric cancer
26481356
ENSG00000148840
PPRC1
cancer
26517683
ENSG00000148840
PPRC1
cancers
26573325
ENSG00000148840
PPRC1
DLBCL
26757888
ENSG00000148840
PPRC1
endometrial cancer
2675940
ENSG00000148840
PPRC1
Cancer
26816824
ENSG00000148840
PPRC1
tumor
27143813
ENSG00000148840
PPRC1
cancer
27239242
ENSG00000148840
PPRC1
cancers
27259231
ENSG00000148840
PPRC1
tumor
27307036
ENSG00000148840
PPRC1
Cancer
27629725
ENSG00000148840
PPRC1
Tumor
27664948
ENSG00000148840
PPRC1
tumour
27884018
ENSG00000148840
PPRC1
tumor
27941796
ENSG00000148840
PPRC1
tumor
28758948
ENSG00000148840
PPRC1
breast cancer
28821609
ENSG00000148840
PPRC1
cancers
28978033
ENSG00000148840
PPRC1
tumor
29259714
ENSG00000148840
PPRC1
neuroendocrine tumors
29352372
ENSG00000148840
PPRC1
cancer
29361779
ENSG00000148840
PPRC1
cancers
29379165
ENSG00000148840
PPRC1
tumors
29415665
ENSG00000148840
PPRC1
endometrial cancer
2944579
ENSG00000148840
PPRC1
thyroid tumor
29662614
ENSG00000148840
PPRC1
tumor
29845708
ENSG00000148840
PPRC1
primary cancer
30250595
ENSG00000148840
PPRC1
cancer
30253781
ENSG00000148840
PPRC1
tumor
30273602
ENSG00000148840
PPRC1
tumor
30515799
ENSG00000148840
PPRC1
breast cancers
30583339
ENSG00000148840
PPRC1
cancer
30706327
ENSG00000148840
PPRC1
cancers
30803482
ENSG00000148840
PPRC1
tumors
30885343
ENSG00000148840
PPRC1
tumor
31181801
ENSG00000148840
PPRC1
gastric cancers
31376239
ENSG00000148840
PPRC1
breast cancer
31548342
ENSG00000148840
PPRC1
tumor
31940477
ENSG00000148840
PPRC1
tumor
6370511
ENSG00000148840
PPRC1
breast cancers
6493199
ENSG00000148840
PPRC1
breast cancers
6876432
ENSG00000148840
PPRC1
tumor
7010927
ENSG00000148840
PPRC1
tumor
8608115
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000148840
PPRC1
MESO
0.0017
high
show
ENSG00000148840
PPRC1
SARC
0.021
high
show
ENSG00000148840
PPRC1
UCEC
0.037
high
show
ENSG00000148840
PPRC1
HNSC
0.041
high
show
ENSG00000148840
PPRC1
LUAD
0.041
high
show
ENSG00000148840
PPRC1
PCPG
0.012
high
show
ENSG00000148840
PPRC1
THYM
0.043
low
show
ENSG00000148840
PPRC1
COAD
0.0036
high
show
ENSG00000148840
PPRC1
ESCA
0.023
low
show
ENSG00000148840
PPRC1
KIRC
0.00064
high
show
ENSG00000148840
PPRC1
BLCA
0.032
high
show
ENSG00000148840
PPRC1
SKCM
0.0028
high
show
ENSG00000148840
PPRC1
LIHC
0.0098
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000148840
PPRC1
LUSC
Del
1.071413
0.071312
0.359233
0.524950
ENSG00000148840
PPRC1
LGG
Del
1.247339
0.044952
0.560342
0.224172
ENSG00000148840
PPRC1
CESC
Del
0.727877
0.067161
0.440934
0.298305
ENSG00000148840
PPRC1
READ
Del
0.723532
0.072833
0.411125
0.303030
ENSG00000148840
PPRC1
COAD
Del
7.771579
0.099383
0.399730
0.237251
ENSG00000148840
PPRC1
HNSC
Del
0.635717
0.053095
0.339102
0.249042
ENSG00000148840
PPRC1
LIHC
Del
1.009656
0.070811
0.480087
0.264865
ENSG00000148840
PPRC1
BLCA
Del
1.539819
0.091548
0.396221
0.411765
ENSG00000148840
PPRC1
BRCA
Del
2.491458
0.078091
0.376899
0.293519
ENSG00000148840
PPRC1
STAD
Del
1.981569
0.078314
0.364282
0.226757
ENSG00000148840
PPRC1
PRAD
Del
3.142162
0.099463
0.445818
0.164634
ENSG00000148840
PPRC1
UCEC
Del
4.067077
0.081550
0.534001
0.133581
ENSG00000148840
PPRC1
MESO
Del
1.599660
0.160531
0.481672
0.321839
ENSG00000148840
PPRC1
OV
Del
11.970762
0.318063
0.554464
0.414508
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