Ensembl ID ENSG00000148773 Gene ID 4288 Accession 7107
Gene Symbol MKI67 Alias KIA;MIB-;MIB-1;PPP1R105 Full Name marker of proliferation Ki-67
Position 10 : 128096659 - 128126423 Length 29765 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary Enables protein C-terminus binding activity. Involved in regulation of chromosome segregation and regulation of mitotic nuclear division. Located in chromosome; nuclear body; and nucleolus. Colocalizes with condensed chromosome. Implicated in Crohn's disease; breast cancer; human immunodeficiency virus infectious disease; and pancreatic cancer. Biomarker of several diseases, including Barrett's esophagus; autoimmune disease of musculoskeletal system (multiple); endocrine gland cancer (multiple); gastrointestinal system cancer (multiple); and interstitial cystitis. [provided by Alliance of Genome Resources, Apr 2022]

ENSG00000148773 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000148773 MKI67 2.21 2.37e-49 KIRC
ENSG00000148773 MKI67 1.14 4.57e-18 HNSC
ENSG00000148773 MKI67 1.94 5.12e-16 BLCA
ENSG00000148773 MKI67 3.08 7.16e-152 BRCA
ENSG00000148773 MKI67 1.03 2.42e-17 COAD
ENSG00000148773 MKI67 3.13 7.48e-21 KICH
ENSG00000148773 MKI67 3.52 6.83e-163 LUSC
ENSG00000148773 MKI67 1.49 8.81e-19 PRAD
ENSG00000148773 MKI67 5.74 7.74e-29 GBM
ENSG00000148773 MKI67 2.50 7.46e-22 KIRP
ENSG00000148773 MKI67 3.35 1.05e-66 LIHC
ENSG00000148773 MKI67 1.85 1.62e-25 STAD
ENSG00000148773 MKI67 3.60 3.95e-97 UCEC
ENSG00000148773 MKI67 3.98 5.13e-32 CHOL
ENSG00000148773 MKI67 5.53 8.53e-48 CESC
ENSG00000148773 MKI67 3.10 6.39e-82 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000148773 MKI67 tumour 10089075
ENSG00000148773 MKI67 tumour 10418718
ENSG00000148773 MKI67 cancer 10840938
ENSG00000148773 MKI67 tumour 10906693
ENSG00000148773 MKI67 phyllodes tumor of the breast 11245343
ENSG00000148773 MKI67 tumor 11517015
ENSG00000148773 MKI67 tumor 12114689
ENSG00000148773 MKI67 Tumours 1315652
ENSG00000148773 MKI67 glial tumors 15654669
ENSG00000148773 MKI67 prostate tumors 15788644
ENSG00000148773 MKI67 breast cancer 15844560
ENSG00000148773 MKI67 tumor 16415998
ENSG00000148773 MKI67 breast cancer 16638850
ENSG00000148773 MKI67 Tumor 17228000
ENSG00000148773 MKI67 tumor 18190825
ENSG00000148773 MKI67 tumour 19035275
ENSG00000148773 MKI67 malignant tumor 19393097
ENSG00000148773 MKI67 tumors 19619298
ENSG00000148773 MKI67 tumour 19755982
ENSG00000148773 MKI67 tumours 21152022
ENSG00000148773 MKI67 breast tumors 21352579
ENSG00000148773 MKI67 prostate cancer 21629784
ENSG00000148773 MKI67 tumors 21958427
ENSG00000148773 MKI67 breast cancer 21960707
ENSG00000148773 MKI67 tumor 22054036
ENSG00000148773 MKI67 tumors 22137483
ENSG00000148773 MKI67 breast cancer 22318550
ENSG00000148773 MKI67 tumor 22458606
ENSG00000148773 MKI67 colorectal cancer 22481684
ENSG00000148773 MKI67 Triple negative breast cancer 22489698
ENSG00000148773 MKI67 tumor 22674438
ENSG00000148773 MKI67 rectal cancer 22711167
ENSG00000148773 MKI67 tumors 22724020
ENSG00000148773 MKI67 tumor 22899882
ENSG00000148773 MKI67 cancer 22956898
ENSG00000148773 MKI67 colon cancer 23134733
ENSG00000148773 MKI67 cancer 23404217
ENSG00000148773 MKI67 tumor 23405241
ENSG00000148773 MKI67 breast cancer 23441166
ENSG00000148773 MKI67 cancers 23504136
ENSG00000148773 MKI67 tumors 23534516
ENSG00000148773 MKI67 tumors 23537295
ENSG00000148773 MKI67 bladder cancer 23571005
ENSG00000148773 MKI67 cancer 23681228
ENSG00000148773 MKI67 tumor 23852808
ENSG00000148773 MKI67 Cancer 23941127
ENSG00000148773 MKI67 tumor 24124424
ENSG00000148773 MKI67 breast cancer 24144752
ENSG00000148773 MKI67 cancers 24337596
ENSG00000148773 MKI67 Tumor 24427291
ENSG00000148773 MKI67 tumour 24455756
ENSG00000148773 MKI67 tumors 24492513
ENSG00000148773 MKI67 tumor 24520381
ENSG00000148773 MKI67 tumours 24528602
ENSG00000148773 MKI67 prostate cancer 24708576
ENSG00000148773 MKI67 non-small cell lung cancer 24975429
ENSG00000148773 MKI67 triple negative breast cancer 25068292
ENSG00000148773 MKI67 breast cancer 25069458
ENSG00000148773 MKI67 breast cancer 25281216
ENSG00000148773 MKI67 tumor 25295115
ENSG00000148773 MKI67 tumors 25469115
ENSG00000148773 MKI67 tumor 25575813
ENSG00000148773 MKI67 cancer 25624062
ENSG00000148773 MKI67 tumor 25769324
ENSG00000148773 MKI67 cancer 25797257
ENSG00000148773 MKI67 tumor 25926948
ENSG00000148773 MKI67 breast cancer 26203261
ENSG00000148773 MKI67 tumor 26219678
ENSG00000148773 MKI67 tumor 26301084
ENSG00000148773 MKI67 tumor 26408707
ENSG00000148773 MKI67 cancer 26717571
ENSG00000148773 MKI67 tumor 26735499
ENSG00000148773 MKI67 tumor 26926676
ENSG00000148773 MKI67 cancer 26984280
ENSG00000148773 MKI67 cancer 27012044
ENSG00000148773 MKI67 tumours 27161333
ENSG00000148773 MKI67 tumor 27199557
ENSG00000148773 MKI67 tumour 27220750
ENSG00000148773 MKI67 tumor 27292193
ENSG00000148773 MKI67 cancer 27349856
ENSG00000148773 MKI67 breast cancer 27389414
ENSG00000148773 MKI67 tumors 27486174
ENSG00000148773 MKI67 tumor 27512993
ENSG00000148773 MKI67 breast cancer 27514658
ENSG00000148773 MKI67 tumor 27542596
ENSG00000148773 MKI67 tumor 27610130
ENSG00000148773 MKI67 tumor 27716314
ENSG00000148773 MKI67 tumor 27776427
ENSG00000148773 MKI67 tumors 27895310
ENSG00000148773 MKI67 breast cancer 28045625
ENSG00000148773 MKI67 breast cancer 28051275
ENSG00000148773 MKI67 tumor 28193205
ENSG00000148773 MKI67 non-small cell lung cancer 28281552
ENSG00000148773 MKI67 tumor 28349831
ENSG00000148773 MKI67 triple-negative breast cancer 28409241
ENSG00000148773 MKI67 breast cancer 28424560
ENSG00000148773 MKI67 breast cancer 28490348
ENSG00000148773 MKI67 Neuroendocrine Tumor 28521422
ENSG00000148773 MKI67 cancer 28545132
ENSG00000148773 MKI67 breast cancer 28659634
ENSG00000148773 MKI67 prostate tumor 28674394
ENSG00000148773 MKI67 tumors 28832682
ENSG00000148773 MKI67 tumor 28881657
ENSG00000148773 MKI67 cancer 28960585
ENSG00000148773 MKI67 breast cancer 28978063
ENSG00000148773 MKI67 breast cancers 28985022
ENSG00000148773 MKI67 tumours 29065106
ENSG00000148773 MKI67 tumor 29187174
ENSG00000148773 MKI67 Cancer 29196733
ENSG00000148773 MKI67 Cancer 29233929
ENSG00000148773 MKI67 tumor 29249638
ENSG00000148773 MKI67 tumor 29283884
ENSG00000148773 MKI67 cancer 29311117
ENSG00000148773 MKI67 tumor 29416773
ENSG00000148773 MKI67 breast cancer 29417930
ENSG00000148773 MKI67 cancer 29511610
ENSG00000148773 MKI67 tumor 29616097
ENSG00000148773 MKI67 cervical cancer 29670400
ENSG00000148773 MKI67 liver cancer 29692627
ENSG00000148773 MKI67 tumor 29725393
ENSG00000148773 MKI67 cancer 29725417
ENSG00000148773 MKI67 tumor 29954406
ENSG00000148773 MKI67 rectal cancer 29956755
ENSG00000148773 MKI67 bladder cancer 29959570
ENSG00000148773 MKI67 tumor 30054476
ENSG00000148773 MKI67 tumors 30062048
ENSG00000148773 MKI67 ER+ breast cancer 30097312
ENSG00000148773 MKI67 tumor 30101194
ENSG00000148773 MKI67 tumor 30116337
ENSG00000148773 MKI67 tumors 30139383
ENSG00000148773 MKI67 tumor 30246018
ENSG00000148773 MKI67 tumor 30266988
ENSG00000148773 MKI67 cancer 30280956
ENSG00000148773 MKI67 breast cancer 30342538
ENSG00000148773 MKI67 prostate cancer 30361641
ENSG00000148773 MKI67 tumors 30417117
ENSG00000148773 MKI67 breast cancer 30502641
ENSG00000148773 MKI67 tumor 30564197
ENSG00000148773 MKI67 tumor 30615637
ENSG00000148773 MKI67 tumors 30621698
ENSG00000148773 MKI67 tumour 30624727
ENSG00000148773 MKI67 tumor 30655856
ENSG00000148773 MKI67 breast cancer 30764831
ENSG00000148773 MKI67 tumors 30808679
ENSG00000148773 MKI67 tumours 30819233
ENSG00000148773 MKI67 tumour 3085342
ENSG00000148773 MKI67 cancer 30904441
ENSG00000148773 MKI67 breast cancers 30906311
ENSG00000148773 MKI67 tumors 30962452
ENSG00000148773 MKI67 tumor 30991985
ENSG00000148773 MKI67 tumors 31138829
ENSG00000148773 MKI67 colorectal cancer 31203132
ENSG00000148773 MKI67 tumor 31207989
ENSG00000148773 MKI67 colorectal cancer 31208298
ENSG00000148773 MKI67 tumor 31244774
ENSG00000148773 MKI67 tumors 31263747
ENSG00000148773 MKI67 tumors 31307414
ENSG00000148773 MKI67 Tumor 31315058
ENSG00000148773 MKI67 tumours 31337055
ENSG00000148773 MKI67 Tumor 31354472
ENSG00000148773 MKI67 tumor 31423237
ENSG00000148773 MKI67 malignant tumors 31452808
ENSG00000148773 MKI67 Cancer 31476594
ENSG00000148773 MKI67 breast cancer 31506496
ENSG00000148773 MKI67 cancer 31519932
ENSG00000148773 MKI67 tumor 31526971
ENSG00000148773 MKI67 cancer 31545448
ENSG00000148773 MKI67 tumor 31572437
ENSG00000148773 MKI67 Gastric Cancer 31632479
ENSG00000148773 MKI67 tumors 31652600
ENSG00000148773 MKI67 AML 7694870
ENSG00000148773 MKI67 tumors 7937875
ENSG00000148773 MKI67 tumor 8275477
ENSG00000148773 MKI67 breast cancer 9329620
ENSG00000148773 MKI67 tumours 9577372
ENSG00000148773 MKI67 tumor 9652910
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000148773 MKI67 SARC 0.00097 high
ENSG00000148773 MKI67 STAD 0.014 low
ENSG00000148773 MKI67 UCEC 0.0088 high
ENSG00000148773 MKI67 THCA 0.038 low
ENSG00000148773 MKI67 READ 0.035 low
ENSG00000148773 MKI67 LUAD 0.00031 high
ENSG00000148773 MKI67 PCPG 0.00075 high
ENSG00000148773 MKI67 THYM 0.00027 low
ENSG00000148773 MKI67 PRAD 0.017 high
ENSG00000148773 MKI67 GBM 0.045 high
ENSG00000148773 MKI67 SKCM 0.0014 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000148773 MKI67 LUAD Del 0.716840 0.051405 0.299479 0.290698
ENSG00000148773 MKI67 LGG Del 16.065735 0.134856 0.574010 0.292398
ENSG00000148773 MKI67 COAD Del 1.378464 0.049932 0.339715 0.223947
ENSG00000148773 MKI67 GBM Del 2.308637 0.070363 0.701748 0.896014
ENSG00000148773 MKI67 LIHC Del 3.023514 0.098902 0.488069 0.278378
ENSG00000148773 MKI67 TGCT Del 1.585317 0.077951 0.379573 0.466667
ENSG00000148773 MKI67 BLCA Del 1.366875 0.088629 0.396332 0.397059
ENSG00000148773 MKI67 BRCA Del 7.343549 0.103854 0.405566 0.282407
ENSG00000148773 MKI67 STAD Del 1.110708 0.066776 0.337148 0.192744
ENSG00000148773 MKI67 UCEC Del 1.916535 0.062468 0.493180 0.109462
ENSG00000148773 MKI67 MESO Del 1.228003 0.146842 0.481010 0.310345
ENSG00000148773 MKI67 OV Del 1.297077 0.188669 0.502538 0.309154