Ensembl ID ENSG00000146731 Gene ID 908 Accession 1620
Gene Symbol CCT6A Alias CCT6;Cctz;HTR3;TCPZ;TCP20;MoDP-2;TTCP20;CCT-zeta;CCT-zeta-1;TCP-1-zeta Full Name chaperonin containing TCP1 subunit 6A
Position 7 : 56051685 - 56063989 Length 12305 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, several pseudogenes of this gene have been located. [provided by RefSeq, Jun 2010]

ENSG00000146731 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000146731 CCT6A 0.77 2.38e-36 BRCA
ENSG00000146731 CCT6A 1.14 3.70e-58 COAD
ENSG00000146731 CCT6A 1.04 1.39e-14 READ
ENSG00000146731 CCT6A 1.62 4.19e-44 LUSC
ENSG00000146731 CCT6A 0.82 1.52e-28 LIHC
ENSG00000146731 CCT6A 0.98 6.88e-17 STAD
ENSG00000146731 CCT6A 0.70 1.15e-17 UCEC
ENSG00000146731 CCT6A 1.09 2.82e-25 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000146731 CCT6A cancer 21651573
ENSG00000146731 CCT6A tumor 23644154
ENSG00000146731 CCT6A cancer 30008265
ENSG00000146731 CCT6A tumour 30578123
ENSG00000146731 CCT6A cancer 30942452
ENSG00000146731 CCT6A cancers 31101846
ENSG00000146731 CCT6A Cancer 31819524
ENSG00000146731 CCT6A cancer 31867042
ENSG00000146731 CCT6A tumor 31934176
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000146731 CCT6A MESO 0.0038 high
ENSG00000146731 CCT6A SARC 0.0052 high
ENSG00000146731 CCT6A UVM 0.0017 high
ENSG00000146731 CCT6A PAAD 0.024 high
ENSG00000146731 CCT6A LUSC 0.0099 low
ENSG00000146731 CCT6A HNSC 0.00064 high
ENSG00000146731 CCT6A READ 0.027 low
ENSG00000146731 CCT6A KICH 0.0019 high
ENSG00000146731 CCT6A BRCA 0.0017 high
ENSG00000146731 CCT6A COAD 0.03 high
ENSG00000146731 CCT6A ESCA 0.017 high
ENSG00000146731 CCT6A OV 0.027 low
ENSG00000146731 CCT6A DLBC 0.00065 low
ENSG00000146731 CCT6A KIRC 0.0034 high
ENSG00000146731 CCT6A PRAD 0.048 high
ENSG00000146731 CCT6A BLCA 0.017 high
ENSG00000146731 CCT6A LAML 0.014 low
ENSG00000146731 CCT6A CESC 0.00013 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000146731 CCT6A LUSC Amp 6.747329 0.340427 0.669997 0.499002
ENSG00000146731 CCT6A LUAD Amp 3.247350 0.173726 0.605850 0.527132
ENSG00000146731 CCT6A GBM Amp 53.144677 0.576619 1.047325 0.816291
ENSG00000146731 CCT6A ESCA Amp 3.373769 0.405736 0.640146 0.657609
ENSG00000146731 CCT6A HNSC Amp 27.489202 0.480523 0.833135 0.406130
ENSG00000146731 CCT6A BLCA Amp 2.143028 0.214143 0.556768 0.450980
ENSG00000146731 CCT6A STAD Amp 0.741622 0.131840 0.536194 0.476190