Ensembl ID
ENSG00000146109
Gene ID
29777
Accession
17369
Gene Symbol
ABT1
Alias
Esf2;hABT1
Full Name
activator of basal transcription 1
Position
6 : 26596953 - 26600739
Length
3787 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs mRNA RBP type
Non-canonical_RBPs
Summary
Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) with the core region of class II promoters. Studies in mouse suggest that the protein encoded by this gene likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA. [provided by RefSeq, Jul 2008]
ENSG00000146109 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000146109
ABT1
0.40
6.51e-21
KIRC
ENSG00000146109
ABT1
0.32
2.54e-11
BRCA
ENSG00000146109
ABT1
0.56
3.11e-11
LUSC
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000146109
ABT1
MESO
0.0051
low
show
ENSG00000146109
ABT1
SARC
0.0037
high
show
ENSG00000146109
ABT1
UVM
0.0048
low
show
ENSG00000146109
ABT1
PAAD
0.0019
low
show
ENSG00000146109
ABT1
UCEC
0.0017
high
show
ENSG00000146109
ABT1
LGG
0.012
high
show
ENSG00000146109
ABT1
READ
0.01
low
show
ENSG00000146109
ABT1
KICH
0.0081
high
show
ENSG00000146109
ABT1
LUAD
0.03
low
show
ENSG00000146109
ABT1
THYM
0.00011
low
show
ENSG00000146109
ABT1
OV
0.00015
low
show
ENSG00000146109
ABT1
BLCA
0.00019
low
show
ENSG00000146109
ABT1
LAML
0.05
high
show
ENSG00000146109
ABT1
GBM
0.027
low
show
ENSG00000146109
ABT1
SKCM
0.049
high
show
ENSG00000146109
ABT1
CESC
0.012
low
show
ENSG00000146109
ABT1
LIHC
0.046
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000146109
ABT1
PAAD
Del
0.817039
0.047660
0.333411
0.380435
ENSG00000146109
ABT1
ESCA
Del
0.711807
0.097085
0.369256
0.271739
ENSG00000146109
ABT1
SKCM
Amp
2.239207
0.168368
0.747535
0.520436
ENSG00000146109
ABT1
LIHC
Amp
1.024083
0.121585
0.740553
0.402703
ENSG00000146109
ABT1
BLCA
Amp
2.042304
0.210945
0.529416
0.291667
ENSG00000146109
ABT1
UVM
Amp
1.976306
0.243776
1.129589
0.537500
ENSG00000146109
ABT1
OV
Amp
2.151915
0.379108
0.711571
0.464594
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