Ensembl ID ENSG00000145907 Gene ID 10146 Accession 30292
Gene Symbol G3BP1 Alias G3BP;HDH-VIII Full Name G3BP stress granule assembly factor 1
Position 5 : 151771045 - 151812911 Length 41867 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]

ENSG00000145907 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000145907 G3BP1 0.61 4.02e-16 COAD
ENSG00000145907 G3BP1 0.48 3.70e-11 STAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000145907 G3BP1 tumors 11146228
ENSG00000145907 G3BP1 cancer 11779432
ENSG00000145907 G3BP1 breast cancer 11888885
ENSG00000145907 G3BP1 breast cancers 12587999
ENSG00000145907 G3BP1 tumors 16091175
ENSG00000145907 G3BP1 tumor 17253181
ENSG00000145907 G3BP1 cancer 17297477
ENSG00000145907 G3BP1 tumor 17696235
ENSG00000145907 G3BP1 tumor 20180532
ENSG00000145907 G3BP1 lung cancer 20424128
ENSG00000145907 G3BP1 cancer 20663914
ENSG00000145907 G3BP1 cancer 21035425
ENSG00000145907 G3BP1 cancer 21351580
ENSG00000145907 G3BP1 pancreatic cancer 21665939
ENSG00000145907 G3BP1 tumors 22110952
ENSG00000145907 G3BP1 tumor 22205990
ENSG00000145907 G3BP1 breast cancer 22447108
ENSG00000145907 G3BP1 cancer 22703643
ENSG00000145907 G3BP1 oral cancer 22902387
ENSG00000145907 G3BP1 cancer 23178402
ENSG00000145907 G3BP1 tumors 23291128
ENSG00000145907 G3BP1 cancers 23341773
ENSG00000145907 G3BP1 cancers 24157923
ENSG00000145907 G3BP1 breast cancer 24321297
ENSG00000145907 G3BP1 cancer 24324649
ENSG00000145907 G3BP1 cancer 24785146
ENSG00000145907 G3BP1 cancers 24998844
ENSG00000145907 G3BP1 tumors 25546138
ENSG00000145907 G3BP1 cancers 25658430
ENSG00000145907 G3BP1 cancer 25669982
ENSG00000145907 G3BP1 tumor 25800057
ENSG00000145907 G3BP1 gastric cancer 25809930
ENSG00000145907 G3BP1 tumor 25962958
ENSG00000145907 G3BP1 cancers 26579374
ENSG00000145907 G3BP1 GBM 26970484
ENSG00000145907 G3BP1 tumor 27174937
ENSG00000145907 G3BP1 breast cancer 27483305
ENSG00000145907 G3BP1 tumor 27904777
ENSG00000145907 G3BP1 Gastric Cancer 28337362
ENSG00000145907 G3BP1 tumor 28394340
ENSG00000145907 G3BP1 cancer 28405179
ENSG00000145907 G3BP1 cancer 28712408
ENSG00000145907 G3BP1 Cancer 29588351
ENSG00000145907 G3BP1 tumor 29717134
ENSG00000145907 G3BP1 cancer 30091651
ENSG00000145907 G3BP1 tumour 30207743
ENSG00000145907 G3BP1 cancers 30458784
ENSG00000145907 G3BP1 cancer 30595162
ENSG00000145907 G3BP1 breast cancer 30971929
ENSG00000145907 G3BP1 esophageal cancer 30989663
ENSG00000145907 G3BP1 cancer 31172368
ENSG00000145907 G3BP1 tumors 31481087
ENSG00000145907 G3BP1 nonsmall cell lung cancer 31560169
ENSG00000145907 G3BP1 gastric cancer 31564899
ENSG00000145907 G3BP1 lung cancer 31704836
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000145907 G3BP1 SARC 0.0014 high
ENSG00000145907 G3BP1 UVM 0.05 high
ENSG00000145907 G3BP1 PAAD 0.0017 high
ENSG00000145907 G3BP1 UCEC 0.0057 high
ENSG00000145907 G3BP1 THCA 3e-04 high
ENSG00000145907 G3BP1 LGG 0.006 high
ENSG00000145907 G3BP1 HNSC 0.03 high
ENSG00000145907 G3BP1 READ 0.00045 low
ENSG00000145907 G3BP1 KIRP 0.00037 low
ENSG00000145907 G3BP1 LUAD 0.0072 high
ENSG00000145907 G3BP1 COAD 0.032 low
ENSG00000145907 G3BP1 ESCA 0.02 high
ENSG00000145907 G3BP1 KIRC 0.0063 low
ENSG00000145907 G3BP1 BLCA 0.00064 high
ENSG00000145907 G3BP1 SKCM 0.012 low
ENSG00000145907 G3BP1 CESC 0.038 high
ENSG00000145907 G3BP1 LIHC 0.0035 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000145907 G3BP1 LAML Del 6.045844 0.088426 0.801010 0.083770
ENSG00000145907 G3BP1 LGG Del 3.176153 0.062258 0.419493 0.107212
ENSG00000145907 G3BP1 ACC Amp 0.822722 0.261266 1.219288 0.666667
ENSG00000145907 G3BP1 SKCM Del 5.810964 0.130685 0.495988 0.337875
ENSG00000145907 G3BP1 KIRC Amp 52.401218 0.297192 0.545160 0.611742