Ensembl ID
ENSG00000145391
Gene ID
80854
Accession
30412
Gene Symbol
SETD7
Alias
KMT7;SET7;SET9;SET7/9
Full Name
SET domain containing 7, histone lysine methyltransferase
Position
4 : 139495941 - 139606699
Length
110759 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs ncRNA RBP type
Non-canonical_RBPs
Summary
Enables histone-lysine N-methyltransferase activity and p53 binding activity. Involved in peptidyl-lysine dimethylation and peptidyl-lysine monomethylation. Acts upstream of or within cellular response to DNA damage stimulus and heterochromatin organization. Located in chromosome and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]
ENSG00000145391 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000145391
SETD7
0.64
1.67e-17
KIRC
ENSG00000145391
SETD7
-1.3
8.90e-16
BLCA
ENSG00000145391
SETD7
-0.9
9.71e-40
BRCA
ENSG00000145391
SETD7
-2.2
2.85e-40
UCEC
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000145391
SETD7
tumor
20121546
ENSG00000145391
SETD7
cancer
20959290
ENSG00000145391
SETD7
tumor
22772057
ENSG00000145391
SETD7
cancer
23509280
ENSG00000145391
SETD7
cancer
23575530
ENSG00000145391
SETD7
Malignant brain tumor
24492612
ENSG00000145391
SETD7
prostate cancer
25189356
ENSG00000145391
SETD7
tumor
25515659
ENSG00000145391
SETD7
breast cancer
25537518
ENSG00000145391
SETD7
cancer
25637186
ENSG00000145391
SETD7
ovarian cancer
25954928
ENSG00000145391
SETD7
cancer
26116705
ENSG00000145391
SETD7
cancers
26390175
ENSG00000145391
SETD7
gastric cancer
26701885
ENSG00000145391
SETD7
cancers
26757928
ENSG00000145391
SETD7
breast cancer
26779630
ENSG00000145391
SETD7
tumor
26848522
ENSG00000145391
SETD7
prostate cancer
26861389
ENSG00000145391
SETD7
tumors
27054335
ENSG00000145391
SETD7
breast cancer
27132511
ENSG00000145391
SETD7
tumor
27183310
ENSG00000145391
SETD7
cancer
28557056
ENSG00000145391
SETD7
Lung Cancer
28819408
ENSG00000145391
SETD7
breast cancer
29212211
ENSG00000145391
SETD7
colorectal cancer
29384474
ENSG00000145391
SETD7
cancer
29498708
ENSG00000145391
SETD7
cancer
29869845
ENSG00000145391
SETD7
cancer
30013796
ENSG00000145391
SETD7
cancers
30106440
ENSG00000145391
SETD7
colorectal cancer
30361067
ENSG00000145391
SETD7
gastric cancer
30674889
ENSG00000145391
SETD7
colorectal cancer
30881498
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000145391
SETD7
MESO
0.013
high
show
ENSG00000145391
SETD7
SARC
0.004
low
show
ENSG00000145391
SETD7
STAD
0.0045
high
show
ENSG00000145391
SETD7
UVM
0.0057
high
show
ENSG00000145391
SETD7
UCEC
0.031
low
show
ENSG00000145391
SETD7
THCA
0.016
high
show
ENSG00000145391
SETD7
LGG
0.012
low
show
ENSG00000145391
SETD7
READ
0.0042
high
show
ENSG00000145391
SETD7
KICH
0.033
high
show
ENSG00000145391
SETD7
LUAD
0.021
high
show
ENSG00000145391
SETD7
THYM
0.0023
low
show
ENSG00000145391
SETD7
BRCA
0.0022
high
show
ENSG00000145391
SETD7
ESCA
0.0072
low
show
ENSG00000145391
SETD7
KIRC
0.00046
low
show
ENSG00000145391
SETD7
BLCA
0.0044
high
show
ENSG00000145391
SETD7
SKCM
0.0077
low
show
ENSG00000145391
SETD7
CESC
0.048
high
show
ENSG00000145391
SETD7
LIHC
0.022
low
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000145391
SETD7
LUSC
Del
2.806415
0.092274
0.383152
0.628743
ENSG00000145391
SETD7
LGG
Del
5.232210
0.076398
0.445525
0.235867
ENSG00000145391
SETD7
BLCA
Del
1.576204
0.092078
0.351367
0.397059
Copyright © 2023, Bioinformatics Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China. All Rights Reserved.