Ensembl ID ENSG00000144566 Gene ID 5868 Accession 9783
Gene Symbol RAB5A Alias RAB5 Full Name RAB5A, member RAS oncogene family
Position 3 : 19947097 - 19985175 Length 38079 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary Enables GDP binding activity; GTP binding activity; and GTPase activity. Involved in several processes, including amyloid-beta clearance by transcytosis; early endosome to late endosome transport; and regulation of exocytosis. Located in several cellular components, including cytoplasmic side of early endosome membrane; nucleoplasm; and terminal bouton. [provided by Alliance of Genome Resources, Apr 2022]

ENSG00000144566 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000144566 RAB5A -0.5 1.20e-23 KIRC
ENSG00000144566 RAB5A -0.7 3.67e-20 HNSC
ENSG00000144566 RAB5A -0.4 7.90e-16 LUSC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000144566 RAB5A lung cancer 10432006
ENSG00000144566 RAB5A gastric cancer 11776829
ENSG00000144566 RAB5A cancer 12901617
ENSG00000144566 RAB5A Tumor 16459650
ENSG00000144566 RAB5A tumor 18160707
ENSG00000144566 RAB5A breast cancer 21500550
ENSG00000144566 RAB5A tumor 24176850
ENSG00000144566 RAB5A ovarian cancer 24877083
ENSG00000144566 RAB5A tumor 25049275
ENSG00000144566 RAB5A cancer 25339198
ENSG00000144566 RAB5A breast cancer 25755726
ENSG00000144566 RAB5A Cancer 26449523
ENSG00000144566 RAB5A primary cancer 26473288
ENSG00000144566 RAB5A pancreatic cancer 28103577
ENSG00000144566 RAB5A cancer 28784136
ENSG00000144566 RAB5A cancer 28849149
ENSG00000144566 RAB5A pancreatic cancer 28867190
ENSG00000144566 RAB5A Colorectal Cancer 30765602
ENSG00000144566 RAB5A gastric cancer 31290727
ENSG00000144566 RAB5A tumor 31387632
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000144566 RAB5A MESO 0.0017 high
ENSG00000144566 RAB5A SARC 0.00016 high
ENSG00000144566 RAB5A UVM 0.00029 low
ENSG00000144566 RAB5A PAAD 0.0023 high
ENSG00000144566 RAB5A LGG 0.015 high
ENSG00000144566 RAB5A LUSC 0.043 high
ENSG00000144566 RAB5A READ 0.022 low
ENSG00000144566 RAB5A KICH 0.017 high
ENSG00000144566 RAB5A PCPG 0.038 low
ENSG00000144566 RAB5A THYM 0.023 low
ENSG00000144566 RAB5A BRCA 0.0032 high
ENSG00000144566 RAB5A ESCA 0.026 high
ENSG00000144566 RAB5A KIRC 0.00065 low
ENSG00000144566 RAB5A PRAD 0.00012 low
ENSG00000144566 RAB5A BLCA 0.0085 low
ENSG00000144566 RAB5A SKCM 0.0025 low
ENSG00000144566 RAB5A LIHC 0.012 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000144566 RAB5A BLCA Amp 2.276005 0.218165 0.520581 0.379902
ENSG00000144566 RAB5A KIRC Del 50.014034 0.177161 0.516482 0.876894
ENSG00000144566 RAB5A OV Del 1.788688 0.198579 0.492895 0.335060