Ensembl ID ENSG00000144231 Gene ID 5433 Accession 9191
Gene Symbol POLR2D Alias RBP4;RPB4;RPB16;HSRBP4;HSRPB4 Full Name RNA polymerase II subunit D
Position 2 : 127843553 - 127858155 Length 14603 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene encodes the fourth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. In yeast, this polymerase subunit is associated with the polymerase under suboptimal growth conditions and may have a stress protective role. A sequence for a ribosomal pseudogene is contained within the 3' untranslated region of the transcript from this gene. [provided by RefSeq, Jul 2008]

ENSG00000144231 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000144231 POLR2D 0.25 3.82e-13 KIRC
ENSG00000144231 POLR2D 0.40 1.08e-21 BRCA
ENSG00000144231 POLR2D 0.79 8.34e-51 COAD
ENSG00000144231 POLR2D 0.88 9.04e-38 LUSC
ENSG00000144231 POLR2D 0.57 3.86e-19 UCEC
ENSG00000144231 POLR2D 0.68 2.16e-28 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000144231 POLR2D Cancer 29196733
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000144231 POLR2D MESO 0.014 high
ENSG00000144231 POLR2D SARC 0.037 high
ENSG00000144231 POLR2D STAD 0.036 low
ENSG00000144231 POLR2D CHOL 0.028 high
ENSG00000144231 POLR2D UVM 0.019 high
ENSG00000144231 POLR2D PAAD 0.049 low
ENSG00000144231 POLR2D UCEC 0.019 high
ENSG00000144231 POLR2D LGG 0.00037 high
ENSG00000144231 POLR2D LUSC 0.0033 low
ENSG00000144231 POLR2D HNSC 0.035 high
ENSG00000144231 POLR2D KICH 0.0015 high
ENSG00000144231 POLR2D THYM 0.0061 low
ENSG00000144231 POLR2D OV 0.0022 low
ENSG00000144231 POLR2D SKCM 0.038 high
ENSG00000144231 POLR2D CESC 0.042 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000144231 POLR2D DLBC Del 0.606686 0.117287 0.514915 0.125000
ENSG00000144231 POLR2D PRAD Del 8.787689 0.141493 0.489149 0.160569
ENSG00000144231 POLR2D OV Del 0.797691 0.176515 0.522878 0.208981