Ensembl ID ENSG00000144029 Gene ID 64969 Accession 14498
Gene Symbol MRPS5 Alias S5mt;uS5m;MRP-S5 Full Name mitochondrial ribosomal protein S5
Position 2 : 95085369 - 95122006 Length 36638 bases Strand Minus strand
Status Confidence Main interacting RNAsrRNARBP type Canonical_RBPs
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S5P family. Pseudogenes corresponding to this gene are found on chromosomes 4q, 5q, and 18q. [provided by RefSeq, Jul 2008]

ENSG00000144029 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000144029 MRPS5 0.45 4.88e-11 LUSC
ENSG00000144029 MRPS5 0.35 1.12e-11 PRAD
ENSG00000144029 MRPS5 0.50 6.46e-17 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000144029 MRPS5 tumor 30901096
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000144029 MRPS5 MESO 0.029 low
ENSG00000144029 MRPS5 SARC 0.044 high
ENSG00000144029 MRPS5 STAD 0.046 low
ENSG00000144029 MRPS5 UVM 0.00016 high
ENSG00000144029 MRPS5 THCA 0.00041 low
ENSG00000144029 MRPS5 ACC 0.00019 high
ENSG00000144029 MRPS5 HNSC 0.0059 high
ENSG00000144029 MRPS5 READ 0.017 high
ENSG00000144029 MRPS5 KICH 0.0016 high
ENSG00000144029 MRPS5 LUAD 0.034 high
ENSG00000144029 MRPS5 PCPG 0.0076 high
ENSG00000144029 MRPS5 THYM 0.0013 low
ENSG00000144029 MRPS5 BRCA 0.0069 low
ENSG00000144029 MRPS5 COAD 0.004 high
ENSG00000144029 MRPS5 OV 0.007 high
ENSG00000144029 MRPS5 DLBC 0.0011 low
ENSG00000144029 MRPS5 LAML 0.036 high
ENSG00000144029 MRPS5 GBM 0.01 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency