Ensembl ID ENSG00000143761 Gene ID 375 Accession 652
Gene Symbol ARF1 Alias PVNH8 Full Name ADP ribosylation factor 1
Position 1 : 228082708 - 228099212 Length 16505 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary ADP-ribosylation factor 1 (ARF1) is a member of the human ARF gene family. The family members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking as activators of phospholipase D. The gene products, including 6 ARF proteins and 11 ARF-like proteins, constitute a family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2 and ARF3), class II (ARF4 and ARF5) and class III (ARF6), and members of each class share a common gene organization. The ARF1 protein is localized to the Golgi apparatus and has a central role in intra-Golgi transport. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

ENSG00000143761 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000143761 ARF1 1.07 2.23e-94 BRCA
ENSG00000143761 ARF1 0.77 1.15e-13 UCEC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000143761 ARF1 cancers 12696062
ENSG00000143761 ARF1 tumor 15495191
ENSG00000143761 ARF1 tumor 15946480
ENSG00000143761 ARF1 tumour 16633337
ENSG00000143761 ARF1 metastatic tumors 17367606
ENSG00000143761 ARF1 breast cancer 18990689
ENSG00000143761 ARF1 breast cancer 21478909
ENSG00000143761 ARF1 Cancer 22158626
ENSG00000143761 ARF1 gastric cancer 22348287
ENSG00000143761 ARF1 tumors 22937144
ENSG00000143761 ARF1 invasive breast cancer 23707487
ENSG00000143761 ARF1 breast cancer 24196838
ENSG00000143761 ARF1 invasive breast cancer 24407288
ENSG00000143761 ARF1 invasive breast cancer 25530216
ENSG00000143761 ARF1 triple negative breast cancer 26176330
ENSG00000143761 ARF1 breast cancer 26473412
ENSG00000143761 ARF1 breast cancer 26908458
ENSG00000143761 ARF1 prostate cancer 27213581
ENSG00000143761 ARF1 cancer 27517156
ENSG00000143761 ARF1 tumor 27769899
ENSG00000143761 ARF1 ovarian cancer 28098897
ENSG00000143761 ARF1 tumor 28631186
ENSG00000143761 ARF1 cancer 29376139
ENSG00000143761 ARF1 breast cancer 29614107
ENSG00000143761 ARF1 tumor 29868251
ENSG00000143761 ARF1 cancer 30735034
ENSG00000143761 ARF1 HNSCC 30777099
ENSG00000143761 ARF1 cervical cancer 31232491
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000143761 ARF1 STAD 0.043 low
ENSG00000143761 ARF1 UCEC 0.0019 low
ENSG00000143761 ARF1 ACC 0.00046 high
ENSG00000143761 ARF1 LGG 0.012 high
ENSG00000143761 ARF1 LUSC 0.047 high
ENSG00000143761 ARF1 HNSC 0.00011 high
ENSG00000143761 ARF1 READ 0.02 high
ENSG00000143761 ARF1 KIRP 0.0032 high
ENSG00000143761 ARF1 BRCA 0.022 high
ENSG00000143761 ARF1 COAD 0.041 low
ENSG00000143761 ARF1 ESCA 0.006 high
ENSG00000143761 ARF1 OV 0.017 low
ENSG00000143761 ARF1 DLBC 0.019 high
ENSG00000143761 ARF1 KIRC 0.014 high
ENSG00000143761 ARF1 PRAD 0.01 high
ENSG00000143761 ARF1 LAML 0.017 high
ENSG00000143761 ARF1 GBM 0.011 high
ENSG00000143761 ARF1 SKCM 0.024 high
ENSG00000143761 ARF1 CESC 0.0083 high
ENSG00000143761 ARF1 LIHC 0.05 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000143761 ARF1 SARC Del 5.373069 0.222849 0.479602 0.334630
ENSG00000143761 ARF1 SKCM Amp 0.864583 0.125323 0.685677 0.512262
ENSG00000143761 ARF1 LIHC Amp 3.136390 0.170740 0.838386 0.708108
ENSG00000143761 ARF1 DLBC Del 1.261269 0.155631 0.560453 0.145833
ENSG00000143761 ARF1 BRCA Amp 10.438360 0.268977 0.790503 0.741667
ENSG00000143761 ARF1 PRAD Del 2.123223 0.089561 0.526672 0.085366
ENSG00000143761 ARF1 UCEC Amp 1.174365 0.115134 0.833256 0.415584
ENSG00000143761 ARF1 OV Amp 4.437633 0.438291 0.716147 0.530225