Ensembl ID
ENSG00000143624
Gene ID
65123
Accession
26153
Gene Symbol
INTS3
Alias
INT3;SOSSA;SOSS-A;C1orf60;C1orf193
Full Name
integrator complex subunit 3
Position
1 : 153728050 - 153774808
Length
46759 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs snRNA RBP type
Canonical_RBPs
Summary
The protein encoded by this gene can form a complex with human single-strand DNA binding proteins 1 or 2 (hSSB1 and hSSB2) and other proteins to mediate genome stability and the DNA damage response. The encoded protein is also part of a multiprotein complex that interacts with the C-terminal domain of RNA polymerase II large subunit to help regulate processing of U1 and U2 small nuclear RNAs. [provided by RefSeq, May 2016]
ENSG00000143624 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000143624
INTS3
-0.8
1.87e-29
KICH
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000143624
INTS3
tumors
18068530
ENSG00000143624
INTS3
cancer
19605351
ENSG00000143624
INTS3
prostate tumor
25609707
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000143624
INTS3
STAD
0.025
low
show
ENSG00000143624
INTS3
UVM
0.025
high
show
ENSG00000143624
INTS3
PAAD
0.00043
low
show
ENSG00000143624
INTS3
UCEC
0.0053
high
show
ENSG00000143624
INTS3
THCA
0.0015
high
show
ENSG00000143624
INTS3
LGG
0.0099
high
show
ENSG00000143624
INTS3
READ
0.04
low
show
ENSG00000143624
INTS3
PCPG
0.0038
high
show
ENSG00000143624
INTS3
THYM
0.00057
high
show
ENSG00000143624
INTS3
COAD
0.00015
high
show
ENSG00000143624
INTS3
UCS
0.027
high
show
ENSG00000143624
INTS3
DLBC
0.00095
high
show
ENSG00000143624
INTS3
LAML
0.025
high
show
ENSG00000143624
INTS3
SKCM
0.00022
high
show
ENSG00000143624
INTS3
CESC
0.014
high
show
ENSG00000143624
INTS3
LIHC
0.016
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000143624
INTS3
CHOL
Amp
0.963900
0.488645
1.029314
0.611111
ENSG00000143624
INTS3
LUSC
Amp
3.660852
0.277381
0.551777
0.528942
ENSG00000143624
INTS3
LUAD
Amp
19.126108
0.385897
0.599841
0.740310
ENSG00000143624
INTS3
CESC
Amp
2.712063
0.201679
0.621250
0.532203
ENSG00000143624
INTS3
ACC
Amp
0.711115
0.248136
0.844417
0.188889
ENSG00000143624
INTS3
READ
Amp
1.132342
0.147656
0.622107
0.278788
ENSG00000143624
INTS3
SARC
Amp
5.032920
0.455563
0.734782
0.396887
ENSG00000143624
INTS3
ESCA
Amp
0.727737
0.261147
0.491940
0.494565
ENSG00000143624
INTS3
SKCM
Amp
3.598737
0.206026
0.685759
0.553134
ENSG00000143624
INTS3
LIHC
Amp
18.527631
0.404884
0.900735
0.751351
ENSG00000143624
INTS3
PCPG
Amp
3.268801
0.113313
0.695367
0.172840
ENSG00000143624
INTS3
TGCT
Amp
0.843213
0.123321
0.448530
0.453333
ENSG00000143624
INTS3
DLBC
Amp
1.306895
0.247389
0.653875
0.250000
ENSG00000143624
INTS3
BLCA
Amp
12.256449
0.431085
0.615770
0.477941
ENSG00000143624
INTS3
BRCA
Amp
21.007460
0.357037
0.791860
0.722222
ENSG00000143624
INTS3
STAD
Amp
2.995477
0.194077
0.474934
0.367347
ENSG00000143624
INTS3
PRAD
Amp
1.748114
0.060651
0.565908
0.079268
ENSG00000143624
INTS3
UCEC
Amp
10.695002
0.254526
0.893887
0.443414
ENSG00000143624
INTS3
OV
Amp
11.809469
0.577009
0.736634
0.616580
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