Ensembl ID
ENSG00000143493
Gene ID
25896
Accession
24484
Gene Symbol
INTS7
Alias
INT7;C1orf73
Full Name
integrator complex subunit 7
Position
1 : 211940399 - 212035557
Length
95159 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs snRNA RBP type
Non-canonical_RBPs
Summary
This gene encodes a subunit of the integrator complex. The integrator complex associates with the C-terminal domain of RNA polymerase II and mediates 3'-end processing of the small nuclear RNAs U1 and U2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
ENSG00000143493 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000143493
INTS7
1.21
1.44e-95
BRCA
ENSG00000143493
INTS7
0.83
3.49e-33
COAD
ENSG00000143493
INTS7
0.86
4.02e-11
READ
ENSG00000143493
INTS7
1.01
2.09e-37
LUSC
ENSG00000143493
INTS7
0.59
5.19e-13
LIHC
ENSG00000143493
INTS7
0.74
1.31e-14
STAD
ENSG00000143493
INTS7
1.11
3.44e-35
UCEC
ENSG00000143493
INTS7
2.20
2.29e-16
CESC
ENSG00000143493
INTS7
0.86
5.80e-32
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000143493
INTS7
tumors
16014973
ENSG00000143493
INTS7
tumor
16971449
ENSG00000143493
INTS7
cancer
23692281
ENSG00000143493
INTS7
cancers
28468258
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000143493
INTS7
UVM
0.018
high
show
ENSG00000143493
INTS7
UCEC
0.018
low
show
ENSG00000143493
INTS7
THCA
0.017
high
show
ENSG00000143493
INTS7
LGG
0.00018
high
show
ENSG00000143493
INTS7
HNSC
0.015
high
show
ENSG00000143493
INTS7
KICH
0.0034
high
show
ENSG00000143493
INTS7
LUAD
0.00045
high
show
ENSG00000143493
INTS7
PCPG
0.0068
high
show
ENSG00000143493
INTS7
UCS
0.012
low
show
ENSG00000143493
INTS7
OV
0.025
low
show
ENSG00000143493
INTS7
KIRC
0.0068
low
show
ENSG00000143493
INTS7
TGCT
0.04
low
show
ENSG00000143493
INTS7
BLCA
0.0082
low
show
ENSG00000143493
INTS7
GBM
0.024
low
show
ENSG00000143493
INTS7
SKCM
0.029
high
show
ENSG00000143493
INTS7
LIHC
0.0028
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000143493
INTS7
SARC
Del
4.457500
0.207262
0.469706
0.315175
ENSG00000143493
INTS7
SKCM
Amp
1.427303
0.144323
0.693771
0.525886
ENSG00000143493
INTS7
LIHC
Amp
4.400573
0.195805
0.849513
0.724324
ENSG00000143493
INTS7
DLBC
Amp
0.878931
0.202301
0.537273
0.270833
ENSG00000143493
INTS7
BRCA
Amp
7.082071
0.235471
0.782184
0.740741
Copyright © 2023, Bioinformatics Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China. All Rights Reserved.